4.2.3.12-RXN

Reaction 4.2.3.12-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-4.2.3.12
• common name:
  • 6-pyruvoyl-tetrahydropterin synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 DIHYDRONEOPTERIN-P3[c] => 1 6-PYRUVOYL-5678-TETRAHYDROPTERIN[c] + 1 P3I[c] + 1 PROTON[c]
• With common name(s):
  • 1 7,8-dihydroneopterin 3'-triphosphate[c] => 1 (6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin[c] + 1 PPPi[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ00075
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ00496
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-7442, drosopterin and aurodrosopterin biosynthesis: PWY-7442
  • 3 reactions found over 7 reactions in the full pathway
• PWY-5664, erythro-tetrahydrobiopterin biosynthesis II: PWY-5664
  • 2 reactions found over 4 reactions in the full pathway
• PWY-5663, erythro-tetrahydrobiopterin biosynthesis I: PWY-5663
  • 3 reactions found over 3 reactions in the full pathway
• PWY-6983, threo-tetrahydrobiopterin biosynthesis: PWY-6983
  • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 22049
• LIGAND-RXN:
  • R04286