DOPAMINE-BETA-MONOOXYGENASE-RXN

Reaction DOPAMINE-BETA-MONOOXYGENASE-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.14.17.1
• common name:
  • dopamine β-monooxygenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 DOPAMINE[c] + 1 OXYGEN-MOLECULE[c] + 1 ASCORBATE[c] => 1 WATER[c] + 1 L-DEHYDRO-ASCORBATE[c] + 1 NOREPINEPHRINE[c]
• With common name(s):
  • 1 H+[c] + 1 dopamine[c] + 1 oxygen[c] + 1 L-ascorbate[c] => 1 H2O[c] + 1 L-dehydro-ascorbate[c] + 1 (R)-noradrenaline[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ08712
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ07432
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ20013
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ03004
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ17674
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13203
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ08322
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ19162
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ03000
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13076
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ03005
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ20015
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ18372
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ20019
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ10458
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY66-301, catecholamine biosynthesis: PWY66-301
  • 2 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 19118
• LIGAND-RXN:
  • R02535
• UNIPROT:
  • Q64237
  • P09172