FGAMSYN-RXN

Reaction FGAMSYN-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-6.3.5.3
• common name:
  • phosphoribosylformylglycinamide synthetase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ATP[c] + 1 5-P-RIBOSYL-N-FORMYLGLYCINEAMIDE[c] + 1 GLN[c] + 1 WATER[c] => 1 ADP[c] + 1 Pi[c] + 1 5-PHOSPHORIBOSYL-N-FORMYLGLYCINEAMIDINE[c] + 1 PROTON[c] + 1 GLT[c]
• With common name(s):
  • 1 ATP[c] + 1 N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide[c] + 1 L-glutamine[c] + 1 H2O[c] => 1 ADP[c] + 1 phosphate[c] + 1 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine[c] + 1 H+[c] + 1 L-glutamate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ09235
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ09236
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Pathways

• PWY-6277, superpathway of 5-aminoimidazole ribonucleotide biosynthesis: PWY-6277
  • 6 reactions found over 9 reactions in the full pathway
• PWY-6121, 5-aminoimidazole ribonucleotide biosynthesis I: PWY-6121
  • 5 reactions found over 5 reactions in the full pathway
• PWY-6122, 5-aminoimidazole ribonucleotide biosynthesis II: PWY-6122
  • 4 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 17129
• LIGAND-RXN:
  • R04463
• UNIPROT:
  • O67691
  • Q9UXW5
  • Q9PNY0
  • O28339
  • Q9PHZ7
  • O26270
  • Q59042
  • Q58660
  • O27427
  • Q9JWC5
  • P35852
  • P38972
  • Q55843
  • Q55037
  • P12041
  • P12042
  • P15254
  • O14228
  • P35421
  • Q9ZB07
  • Q9ZB06