HISTCYCLOHYD-RXN

Reaction HISTCYCLOHYD-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-3.5.4.19
• common name:
  • phosphoribosyl-AMP cyclohydrolase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PHOSPHORIBOSYL-AMP[c] + 1 WATER[c] => 1 PHOSPHORIBOSYL-FORMIMINO-AICAR-P[c]
• With common name(s):
  • 1 1-(5-phospho-β-D-ribosyl)-AMP[c] + 1 H2O[c] => 1 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ07444
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-ectocarpus_siliculosus

Pathways

• HISTSYN-PWY, L-histidine biosynthesis: HISTSYN-PWY
  • 10 reactions found over 10 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 20050
• LIGAND-RXN:
  • R04037
• UNIPROT:
  • P44434
  • Q9JVH6
  • Q9X0C5
  • Q9PM71
  • Q02130
  • Q9RWD6
  • Q58825
  • O28329
  • O34912
  • P0A5B3
  • Q9HUB7
  • Q9KSW7
  • Q9K0H5
  • O67780
  • Q9PBD1
  • Q50837
  • Q53158
  • P45353
  • Q12670
  • P00815
  • P07685
  • O59667
  • Q9X7C3
  • O82768
  • P10367
  • P06989