KETOGLUTREDUCT-RXN

Reaction KETOGLUTREDUCT-RXN

• direction:
  • REVERSIBLE
• ec number:
  • EC-1.1.1.399
• common name:
  • 2-oxoglutarate reductase ((R)-2-hydroxyglutarate-forming)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 R-2-HYDROXYGLUTARATE[c] <=> 1 2-KETOGLUTARATE[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 NAD+[c] + 1 (R)-2-hydroxyglutarate[c] <=> 1 2-oxoglutarate[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ09109
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ13526
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ02143
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ13642
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Pathways

• P162-PWY, L-glutamate degradation V (via hydroxyglutarate): P162-PWY
  • 7 reactions found over 11 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 49615
• LIGAND-RXN:
  • R11337