O-SUCCHOMOSERLYASE-RXN

Reaction O-SUCCHOMOSERLYASE-RXN

• direction:
  • REVERSIBLE
• ec number:
  • EC-2.5.1.48
• common name:
  • cystathionine gamma-synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CYS[c] + 1 O-SUCCINYL-L-HOMOSERINE[c] <=> 1 L-CYSTATHIONINE[c] + 1 SUC[c] + 1 PROTON[c]
• With common name(s):
  • 1 L-cysteine[c] + 1 O-succinyl-L-homoserine[c] <=> 1 L-cystathionine[c] + 1 succinate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ05357
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ20026
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ05358
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• HOMOSER-METSYN-PWY, L-methionine biosynthesis I: HOMOSER-METSYN-PWY
  • 4 reactions found over 7 reactions in the full pathway
• PWY-I9, L-cysteine biosynthesis VI (from L-methionine): PWY-I9
  • 4 reactions found over 7 reactions in the full pathway
• PWY-801, homocysteine and cysteine interconversion: PWY-801
  • 3 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 20397
• LIGAND-RXN:
  • R03260
• UNIPROT:
  • P0A4K2
  • Q9CEC6
  • P38675
  • P24601
  • P00935
  • O04981
  • O04982
  • O81334
  • Q79VD9