RXN-10614

Reaction RXN-10614

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-2.8.2.1
• common name:
  • L-thyroxine sulfotransferase
  • aryl sulfotransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PAPS[c] + 1 L-THYROXINE[c] => 1 CPD-11407[c] + 1 3-5-ADP[c] + 1 PROTON[c]
• With common name(s):
  • 1 3'-phosphoadenylyl-sulfate[c] + 1 L-thyroxine[c] => 1 thyroxine sulfate[c] + 1 adenosine 3',5'-bisphosphate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ06276
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ07550
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ19194
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ01900
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ05841
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ10094
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ00192
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Pathways

• PWY-6261, thyroid hormone metabolism II (via conjugation and/or degradation): PWY-6261
  • 10 reactions found over 15 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 26423