RXN-12789

Reaction RXN-12789

• direction:
  • REVERSIBLE
• ec number:
  • EC-1.1.1.145
• common name:
  • 3-beta-hydroxy-delta5-steroid dehydrogenase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 CPD-4143[c] + 1 NAD[c] <=> 1 CPD-13793[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 sitosterol[c] + 1 NAD+[c] <=> 1 3-oxo-24-ethyl-cholest-5-ene[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ10400
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21137
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21972
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ05616
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ04385
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ01092
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19806
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ08509
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ16241
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ10476
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03341
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ17700
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ04782
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ21018
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ21834
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ03340
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ02713
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06332
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ19982
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM

Pathways

• PWY-6948, sitosterol degradation to androstenedione: PWY-6948
  • 2 reactions found over 18 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools