RXN0-1132

Reaction RXN0-1132

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.8.1.4
• common name:
  • pyruvate dehydrogenase (NAD+)
  • lipoate acetyltransferase N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 Pyruvate-dehydrogenase-dihydrolipoate[c] + 1 NAD[c] => 1 Pyruvate-dehydrogenase-lipoate[c] + 1 NADH[c] + 1 PROTON[c]
• With common name(s):
  • 1 a [pyruvate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] + 1 NAD+[c] => 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 1 NADH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ01042
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ06474
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ10661
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ00971
  • Source: annotation-saccharina_japonica_genome
    • Assignment: GO-TERM
• Gene: SJ13629
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ03718
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER

Pathways

• PYRUVDEHYD-PWY, pyruvate decarboxylation to acetyl CoA: PYRUVDEHYD-PWY
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools