RXN3O-130

Reaction RXN3O-130

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-1.14.13.70
• common name:
  • lanosterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 LANOSTEROL[c] + 3 OXYGEN-MOLECULE[c] + 3 NADPH[c] + 2 PROTON[c] => 1 44-DIMETHYL-CHOLESTA-814-24-TRIENOL[c] + 1 FORMATE[c] + 3 NADP[c] + 4 WATER[c]
• With common name(s):
  • 1 lanosterol[c] + 3 oxygen[c] + 3 NADPH[c] + 2 H+[c] => 1 4,4-dimethyl-cholesta-8,14,24-trienol[c] + 1 formate[c] + 3 NADP+[c] + 4 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ05072
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-6074, zymosterol biosynthesis: PWY-6074
  • 6 reactions found over 12 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 25287
• LIGAND-RXN:
  • R05640