SERINE-C-PALMITOYLTRANSFERASE-RXN

Reaction SERINE-C-PALMITOYLTRANSFERASE-RXN

• direction:
  • LEFT-TO-RIGHT
• ec number:
  • EC-2.3.1.50
• common name:
  • serine palmitoyltransferase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 PROTON[c] + 1 SER[c] + 1 PALMITYL-COA[c] => 1 DEHYDROSPHINGANINE[c] + 1 CO-A[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 H+[c] + 1 L-serine[c] + 1 palmitoyl-CoA[c] => 1 3-dehydrosphinganine[c] + 1 coenzyme A[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: SJ01689
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
• Gene: SJ05058
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
• Gene: SJ01690
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-ectocarpus_siliculosus
• Gene: SJ13300
  • Source: annotation-saccharina_japonica_genome
    • Assignment: EC-NUMBER
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-ectocarpus_siliculosus

Pathways

• PWY-5129, sphingolipid biosynthesis (plants): PWY-5129
  • 4 reactions found over 13 reactions in the full pathway
• SPHINGOLIPID-SYN-PWY, sphingolipid biosynthesis (yeast): SPHINGOLIPID-SYN-PWY
  • 4 reactions found over 8 reactions in the full pathway
• PWY3DJ-12, ceramide de novo biosynthesis: PWY3DJ-12
  • 2 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-saccharina_japonica_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 14762
• LIGAND-RXN:
  • R01281
• UNIPROT:
  • P25045
  • O15270
  • P48241
  • Q09925
  • P40970
  • Q9XVI6
  • Q20375
  • Q9M304