View source for GLUTATHIONE-REDUCT-NADPH-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTATHIONE-REDUCT-NADPH-RXN GLUTATHIONE-REDUCT-NADPH-RXN] ==
* direction:
** LEFT-TO-RIGHT
* common name:
** glutathione_reductase
* ec number:
** [http://enzyme.expasy.org/EC/1.8.1.7 EC-1.8.1.7]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[PROTON]][c] '''+''' 1 [[OXIDIZED-GLUTATHIONE]][c] '''+''' 1 [[NADPH]][c] '''=>''' 2 [[GLUTATHIONE]][c] '''+''' 1 [[NADP]][c]
* With common name(s):
** 1 H+[c] '''+''' 1 glutathione disulfide[c] '''+''' 1 NADPH[c] '''=>''' 2 glutathione[c] '''+''' 1 NADP+[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Tiso_gene_2804]]
** Source: [[annotation-in-silico_annotation]]
*** Assignment: EC-NUMBER
** Source: [[annotation-experimental_annotation]]
*** Assignment: EC-NUMBER
** Source: [[orthology-athaliana]]
* Gene: [[Tiso_gene_12533]]
** Source: [[annotation-in-silico_annotation]]
*** Assignment: EC-NUMBER
** Source: [[annotation-experimental_annotation]]
*** Assignment: EC-NUMBER
** Source: [[orthology-athaliana]]
** Source: [[orthology-esiliculosus]]
== Pathways  ==
* [[GLUT-REDOX-PWY]], glutathione-glutaredoxin redox reactions: [http://metacyc.org/META/NEW-IMAGE?object=GLUT-REDOX-PWY GLUT-REDOX-PWY]
** '''2''' reactions found over '''2''' reactions in the full pathway
* [[PWY-4081]], glutathione-peroxide redox reactions: [http://metacyc.org/META/NEW-IMAGE?object=PWY-4081 PWY-4081]
** '''3''' reactions found over '''3''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[orthology]]
** Source: [[orthology-athaliana]]
*** Tool: [[pantograph]]
** Source: [[orthology-esiliculosus]]
*** Tool: [[pantograph]]
* Category: [[manual]]
** Source: [[manual-primary_network]]
* Category: [[annotation]]
** Source: [[annotation-in-silico_annotation]]
*** Tool: [[pathwaytools]]
** Source: [[annotation-experimental_annotation]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11740 11740]
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R00115 R00115]
* UNIPROT:
** [http://www.uniprot.org/uniprot/P43783 P43783]
** [http://www.uniprot.org/uniprot/Q9CH92 Q9CH92]
** [http://www.uniprot.org/uniprot/P48639 P48639]
** [http://www.uniprot.org/uniprot/P11804 P11804]
** [http://www.uniprot.org/uniprot/P06715 P06715]
** [http://www.uniprot.org/uniprot/P23189 P23189]
** [http://www.uniprot.org/uniprot/P80461 P80461]
** [http://www.uniprot.org/uniprot/Q60151 Q60151]
** [http://www.uniprot.org/uniprot/P41921 P41921]
** [http://www.uniprot.org/uniprot/Q9TWE1 Q9TWE1]
** [http://www.uniprot.org/uniprot/O64409 O64409]
** [http://www.uniprot.org/uniprot/Q43621 Q43621]
** [http://www.uniprot.org/uniprot/P48640 P48640]
** [http://www.uniprot.org/uniprot/Q43154 Q43154]
** [http://www.uniprot.org/uniprot/Q93379 Q93379]
** [http://www.uniprot.org/uniprot/P78965 P78965]
** [http://www.uniprot.org/uniprot/P42770 P42770]
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=glutathione_reductase}}
{{#set: ec number=EC-1.8.1.7}}
{{#set: gene associated=Tiso_gene_2804|Tiso_gene_12533}}
{{#set: in pathway=GLUT-REDOX-PWY|PWY-4081}}
{{#set: reconstruction category=orthology|manual|annotation}}
{{#set: reconstruction source=annotation-in-silico_annotation|manual-primary_network|annotation-experimental_annotation|orthology-athaliana|orthology-esiliculosus}}
{{#set: reconstruction tool=pantograph|pathwaytools}}