View source for METHYLMALONYL-COA-MUT-RXN

[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLMALONYL-COA-MUT-RXN METHYLMALONYL-COA-MUT-RXN] ==
* direction:
** REVERSIBLE
* common name:
** methylmalonyl-_mitochondrial
* ec number:
** [http://enzyme.expasy.org/EC/5.4.99.2 EC-5.4.99.2]
* Synonym(s):

== Reaction Formula ==
* With identifiers:
** 1 [[METHYL-MALONYL-COA]][c] '''<=>''' 1 [[SUC-COA]][c]
* With common name(s):
** 1 (R)-methylmalonyl-CoA[c] '''<=>''' 1 succinyl-CoA[c]

== Genes associated with this reaction  ==
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Tiso_gene_9771]]
** Source: [[annotation-in-silico_annotation]]
*** Assignment: EC-NUMBER
** Source: [[annotation-experimental_annotation]]
*** Assignment: EC-NUMBER
== Pathways  ==
* [[PWY0-43]], conversion of succinate to propanoate: [http://metacyc.org/META/NEW-IMAGE?object=PWY0-43 PWY0-43]
** '''1''' reactions found over '''3''' reactions in the full pathway
* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
** '''7''' reactions found over '''12''' reactions in the full pathway
* [[PWY-5743]], 3-hydroxypropanoate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5743 PWY-5743]
** '''4''' reactions found over '''11''' reactions in the full pathway
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
** '''11''' reactions found over '''18''' reactions in the full pathway
* [[P108-PWY]], pyruvate fermentation to propanoate I: [http://metacyc.org/META/NEW-IMAGE?object=P108-PWY P108-PWY]
** '''3''' reactions found over '''7''' reactions in the full pathway
* [[PWY-5789]], 3-hydroxypropanoate/4-hydroxybutanate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5789 PWY-5789]
** '''8''' reactions found over '''16''' reactions in the full pathway
* [[PROPIONMET-PWY]], propanoyl CoA degradation I: [http://metacyc.org/META/NEW-IMAGE?object=PROPIONMET-PWY PROPIONMET-PWY]
** '''2''' reactions found over '''3''' reactions in the full pathway
== Reconstruction information  ==
* Category: [[annotation]]
** Source: [[annotation-in-silico_annotation]]
*** Tool: [[pathwaytools]]
** Source: [[annotation-experimental_annotation]]
*** Tool: [[pathwaytools]]
== External links  ==
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22888 22888]
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R00833 R00833]
* UNIPROT:
** [http://www.uniprot.org/uniprot/Q05064 Q05064]
** [http://www.uniprot.org/uniprot/P22033 P22033]
** [http://www.uniprot.org/uniprot/Q05065 Q05065]
** [http://www.uniprot.org/uniprot/O74009 O74009]
** [http://www.uniprot.org/uniprot/Q9YBB0 Q9YBB0]
** [http://www.uniprot.org/uniprot/Q9V0E8 Q9V0E8]
** [http://www.uniprot.org/uniprot/Q9RV41 Q9RV41]
** [http://www.uniprot.org/uniprot/O28068 O28068]
** [http://www.uniprot.org/uniprot/Q59676 Q59676]
** [http://www.uniprot.org/uniprot/Q59677 Q59677]
** [http://www.uniprot.org/uniprot/P11652 P11652]
** [http://www.uniprot.org/uniprot/P11653 P11653]
** [http://www.uniprot.org/uniprot/P16332 P16332]
{{#set: direction=REVERSIBLE}}
{{#set: common name=methylmalonyl-_mitochondrial}}
{{#set: ec number=EC-5.4.99.2}}
{{#set: gene associated=Tiso_gene_9771}}
{{#set: in pathway=PWY0-43|PWY-7384|PWY-5743|PWY-6728|P108-PWY|PWY-5789|PROPIONMET-PWY}}
{{#set: reconstruction category=annotation}}
{{#set: reconstruction source=annotation-in-silico_annotation|annotation-experimental_annotation}}
{{#set: reconstruction tool=pathwaytools}}