Difference between revisions of "Tiso gene 11630"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADENOSYL-P4 ADENOSYL-P4] == * smiles: ** C(C1(C(C(C(O1)N3(C=NC2(C(=NC=NC=23)N)))O)O))OP(OP(OP(O...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PROGESTERONE-5-ALPHA-REDUCTASE-RXN PROGESTERONE-5-ALPHA-REDUCTASE-RXN] == * direction: ** LEFT-TO-R...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADENOSYL-P4 ADENOSYL-P4] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PROGESTERONE-5-ALPHA-REDUCTASE-RXN PROGESTERONE-5-ALPHA-REDUCTASE-RXN] ==
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* smiles:
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* direction:
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** C(C1(C(C(C(O1)N3(C=NC2(C(=NC=NC=23)N)))O)O))OP(OP(OP(OP(OCC4(C(C(C(O4)N6(C=NC5(C(=NC=NC=56)N)))O)O))([O-])=O)([O-])=O)([O-])=O)([O-])=O
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=YOAHKNVSNCMZGQ-XPWFQUROSA-J
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* common name:
 
* common name:
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** 5',5'''-diadenosine tetraphosphate
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** 3-oxo-5-alpha-steroid_4-dehydrogenase
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* molecular weight:
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* ec number:
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** 832.36   
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** [http://enzyme.expasy.org/EC/1.3.1.22 EC-1.3.1.22]
 
* Synonym(s):
 
* Synonym(s):
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** Ap4A
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** steroid 5-α-reductase
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** AppppA
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** Δ4-steroid 5α-reductase (progesterone)
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** P(1),P(4)-bis(5'-adenosyl)tetraphosphate
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** P1,P4-bis(5'-adenosyl)tetraphosphate
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[3.6.1.41-RXN]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[PROTON]][c] '''+''' 1 [[PROGESTERONE]][c] '''+''' 1 [[NADPH]][c] '''=>''' 1 [[CPD-293]][c] '''+''' 1 [[NADP]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 H+[c] '''+''' 1 progesterone[c] '''+''' 1 NADPH[c] '''=>''' 1 5-α-pregnane-3,20-dione[c] '''+''' 1 NADP+[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* [[Tiso_gene_14327]]
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** IN-SILICO_ANNOTATION
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***AUTOMATED-NAME-MATCH
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== Pathways  ==
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* [[PWY-6032]], cardenolide biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6032 PWY-6032]
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** '''1''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-7455]], allopregnanolone biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7455 PWY-7455]
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** '''1''' reactions found over '''2''' reactions in the full pathway
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== Reconstruction information  ==
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* [[annotation]]:
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** [[pathwaytools]]:
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*** [[in-silico_annotation]]
 
== External links  ==
 
== External links  ==
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* BIGG : ap4a
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* RHEA:
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* PUBCHEM:
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21952 21952]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25243905 25243905]
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* LIGAND-RXN:
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* HMDB : HMDB01211
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** [http://www.genome.jp/dbget-bin/www_bget?R02208 R02208]
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* LIGAND-CPD:
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{{#set: direction=LEFT-TO-RIGHT}}
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** [http://www.genome.jp/dbget-bin/www_bget?C01260 C01260]
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{{#set: common name=3-oxo-5-alpha-steroid_4-dehydrogenase}}
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* CHEBI:
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{{#set: ec number=EC-1.3.1.22}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58141 58141]
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{{#set: common name=steroid 5-α-reductase|Δ4-steroid 5α-reductase (progesterone)}}
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* METABOLIGHTS : MTBLC58141
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{{#set: gene associated=Tiso_gene_14327}}
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{{#set: smiles=C(C1(C(C(C(O1)N3(C=NC2(C(=NC=NC=23)N)))O)O))OP(OP(OP(OP(OCC4(C(C(C(O4)N6(C=NC5(C(=NC=NC=56)N)))O)O))([O-])=O)([O-])=O)([O-])=O)([O-])=O}}
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{{#set: in pathway=PWY-6032|PWY-7455}}
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{{#set: inchi key=InChIKey=YOAHKNVSNCMZGQ-XPWFQUROSA-J}}
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{{#set: reconstruction category=annotation}}
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{{#set: common name=5',5'''-diadenosine tetraphosphate}}
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{{#set: reconstruction tool=pathwaytools}}
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{{#set: molecular weight=832.36    }}
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{{#set: reconstruction source=in-silico_annotation}}
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{{#set: common name=Ap4A|AppppA|P(1),P(4)-bis(5'-adenosyl)tetraphosphate|P1,P4-bis(5'-adenosyl)tetraphosphate}}
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{{#set: consumed by=3.6.1.41-RXN}}
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Revision as of 18:34, 10 January 2018

Reaction PROGESTERONE-5-ALPHA-REDUCTASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-oxo-5-alpha-steroid_4-dehydrogenase
  • ec number:
  • Synonym(s):
    • steroid 5-α-reductase
    • Δ4-steroid 5α-reductase (progesterone)

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 H+[c] + 1 progesterone[c] + 1 NADPH[c] => 1 5-α-pregnane-3,20-dione[c] + 1 NADP+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6032, cardenolide biosynthesis: PWY-6032
    • 1 reactions found over 3 reactions in the full pathway
  • PWY-7455, allopregnanolone biosynthesis: PWY-7455
    • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

External links





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