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| − | [[Category:Reaction]] | + | [[Category:Metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=OHMETHYLBILANESYN-RXN OHMETHYLBILANESYN-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=BCAA-dehydrogenase-2MB-DH-lipoyl BCAA-dehydrogenase-2MB-DH-lipoyl] == |
| − | * direction:
| + | |
| − | ** LEFT-TO-RIGHT
| + | |
| | * common name: | | * common name: |
| − | ** hydroxymethylbilane_synthase | + | ** an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylbutanoyl]dihydrolipoyl-L-lysine |
| − | ** uroporphyrinogen_synthase
| + | |
| − | * ec number:
| + | |
| − | ** [http://enzyme.expasy.org/EC/2.5.1.61 EC-2.5.1.61]
| + | |
| | * Synonym(s): | | * Synonym(s): |
| | | | |
| − | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
| − | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
| − | ** 4 [[PORPHOBILINOGEN]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[HYDROXYMETHYLBILANE]][c] '''+''' 4 [[AMMONIUM]][c]
| + | == Reaction(s) of unknown directionality == |
| − | * With common name(s):
| + | * [[METHYLVALERATE-RXN]] |
| − | ** 4 porphobilinogen[c] '''+''' 1 H2O[c] '''=>''' 1 preuroporphyrinogen[c] '''+''' 4 ammonium[c]
| + | |
| − | | + | |
| − | == Genes associated with this reaction == | + | |
| − | Genes have been associated with this reaction based on different elements listed below.
| + | |
| − | * [[Tiso_gene_11630]]
| + | |
| − | ** IN-SILICO_ANNOTATION
| + | |
| − | ***AUTOMATED-NAME-MATCH
| + | |
| − | * [[Tiso_gene_14709]]
| + | |
| − | ** IN-SILICO_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | ** EXPERIMENTAL_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | ** [[pantograph]]-[[athaliana]]
| + | |
| − | ** [[pantograph]]-[[synechocystis]]
| + | |
| − | ** [[pantograph]]-[[esiliculosus]]
| + | |
| − | ** [[pantograph]]-[[creinhardtii]]
| + | |
| − | == Pathways == | + | |
| − | * [[PWY-5189]], tetrapyrrole biosynthesis II (from glycine): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5189 PWY-5189]
| + | |
| − | ** '''3''' reactions found over '''4''' reactions in the full pathway
| + | |
| − | * [[PWY-5188]], tetrapyrrole biosynthesis I (from glutamate): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5188 PWY-5188]
| + | |
| − | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
| − | == Reconstruction information == | + | |
| − | * [[orthology]]: | + | |
| − | ** [[pantograph]]:
| + | |
| − | *** [[creinhardtii]]
| + | |
| − | *** [[synechocystis]]
| + | |
| − | *** [[esiliculosus]]
| + | |
| − | *** [[athaliana]]
| + | |
| − | * [[manual]]:
| + | |
| − | ** [[primary_network]]
| + | |
| − | * [[annotation]]:
| + | |
| − | ** [[pathwaytools]]:
| + | |
| − | *** [[experimental_annotation]]
| + | |
| − | *** [[in-silico_annotation]]
| + | |
| | == External links == | | == External links == |
| − | * RHEA:
| + | {{#set: common name=an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylbutanoyl]dihydrolipoyl-L-lysine}} |
| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=13185 13185]
| + | {{#set: reversible reaction associated=METHYLVALERATE-RXN}} |
| − | * LIGAND-RXN:
| + | |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?R00084 R00084]
| + | |
| − | * UNIPROT:
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q57989 Q57989]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O29026 O29026]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P64336 P64336]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9ZMJ7 Q9ZMJ7]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9PHW9 Q9PHW9]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9JVS4 Q9JVS4]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P28464 P28464]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9K0P6 Q9K0P6]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P56140 P56140]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9Y9J0 Q9Y9J0]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9RRY0 Q9RRY0]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O26960 O26960]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9ZD77 Q9ZD77]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P06983 P06983]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P13446 P13446]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P08397 P08397]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P22907 P22907]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P19356 P19356]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q43082 Q43082]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P40129 P40129]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P30527 P30527]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P28789 P28789]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q60169 Q60169]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q43316 Q43316]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q49808 Q49808]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P73660 P73660]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9WX16 Q9WX16]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q09899 Q09899]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9ZND1 Q9ZND1]
| + | |
| − | {{#set: direction=LEFT-TO-RIGHT}}
| + | |
| − | {{#set: common name=hydroxymethylbilane_synthase}} | + | |
| − | {{#set: common name=uroporphyrinogen_synthase}}
| + | |
| − | {{#set: ec number=EC-2.5.1.61}}
| + | |
| − | {{#set: gene associated=Tiso_gene_11630|Tiso_gene_14709}}
| + | |
| − | {{#set: in pathway=PWY-5189|PWY-5188}}
| + | |
| − | {{#set: reconstruction category=orthology}} | + | |
| − | {{#set: reconstruction tool=pantograph}}
| + | |
| − | {{#set: reconstruction source=creinhardtii|synechocystis|esiliculosus|athaliana}}
| + | |
| − | {{#set: reconstruction category=manual}}
| + | |
| − | {{#set: reconstruction source=primary_network}}
| + | |
| − | {{#set: reconstruction category=annotation}}
| + | |
| − | {{#set: reconstruction tool=pathwaytools}}
| + | |
| − | {{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
| + | |
