Difference between revisions of "RXN-10721"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.1.27-RXN 1.2.1.27-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** methylmalonate-semial...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-10721 RXN-10721] == * direction: ** REVERSIBLE * common name: ** 3-hydroxy-L-kynurenine-oxoglut...")
 
(One intermediate revision by the same user not shown)
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[[Category:Reaction]]
 
[[Category:Reaction]]
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.1.27-RXN 1.2.1.27-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-10721 RXN-10721] ==
 
* direction:
 
* direction:
−
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* common name:
 
* common name:
−
** methylmalonate-semialdehyde_dehydrogenase
+
** 3-hydroxy-L-kynurenine-oxoglutarate transaminase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.2.1.27 EC-1.2.1.27]
+
** [http://enzyme.expasy.org/EC/2.6.1.7 EC-2.6.1.7]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[NAD]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[CPD-12179]][c] '''+''' 1 [[WATER]][c] '''=>''' 1 [[NADH]][c] '''+''' 1 [[HCO3]][c] '''+''' 1 [[PROPIONYL-COA]][c] '''+''' 1 [[PROTON]][c]
+
** 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[3-HYDROXY-L-KYNURENINE]][c] '''<=>''' 1 [[CPD-11552]][c] '''+''' 1 [[GLT]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 NAD+[c] '''+''' 1 coenzyme A[c] '''+''' 1 methylmalonate semialdehyde[c] '''+''' 1 H2O[c] '''=>''' 1 NADH[c] '''+''' 1 hydrogencarbonate[c] '''+''' 1 propanoyl-CoA[c] '''+''' 1 H+[c]
+
** 1 2-oxoglutarate[c] '''+''' 1 3-hydroxy-L-kynurenine[c] '''<=>''' 1 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate[c] '''+''' 1 L-glutamate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Tiso_gene_11323]]
+
* Gene: [[Tiso_gene_15680]]
−
** IN-SILICO_ANNOTATION
+
** Source: [[orthology-esiliculosus]]
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***AUTOMATED-NAME-MATCH
+
−
** [[pantograph]]-[[esiliculosus]]
+
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-5642]], 2,4-dinitrotoluene degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5642 PWY-5642]
+
* [[PWY-6309]], L-tryptophan degradation XI (mammalian, via kynurenine): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6309 PWY-6309]
−
** '''1''' reactions found over '''7''' reactions in the full pathway
+
** '''9''' reactions found over '''17''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
−
* Category: [[annotation]]
 
−
** Source: [[annotation-in-silico_annotation]]
 
−
*** Tool: [[pathwaytools]]
 
 
== External links  ==
 
== External links  ==
−
* RHEA:
 
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=20804 20804]
 
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R00922 R00922]
+
** [http://www.genome.jp/dbget-bin/www_bget?R04171 R04171]
−
* UNIPROT:
+
{{#set: direction=REVERSIBLE}}
−
** [http://www.uniprot.org/uniprot/Q02253 Q02253]
+
{{#set: common name=3-hydroxy-L-kynurenine-oxoglutarate transaminase}}
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** [http://www.uniprot.org/uniprot/Q07536 Q07536]
+
{{#set: ec number=EC-2.6.1.7}}
−
** [http://www.uniprot.org/uniprot/P28810 P28810]
+
{{#set: gene associated=Tiso_gene_15680}}
−
** [http://www.uniprot.org/uniprot/O49218 O49218]
+
{{#set: in pathway=PWY-6309}}
−
** [http://www.uniprot.org/uniprot/Q7KW39 Q7KW39]
+
{{#set: reconstruction category=orthology}}
−
{{#set: direction=LEFT-TO-RIGHT}}
+
{{#set: reconstruction source=orthology-esiliculosus}}
−
{{#set: common name=methylmalonate-semialdehyde_dehydrogenase}}
+
{{#set: reconstruction tool=pantograph}}
−
{{#set: ec number=EC-1.2.1.27}}
+
−
{{#set: gene associated=Tiso_gene_11323}}
+
−
{{#set: in pathway=PWY-5642}}
+
−
{{#set: reconstruction category=orthology|annotation}}
+
−
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
+
−
{{#set: reconstruction tool=pantograph|pathwaytools}}
+

Latest revision as of 19:18, 21 March 2018

Reaction RXN-10721

  • direction:
    • REVERSIBLE
  • common name:
    • 3-hydroxy-L-kynurenine-oxoglutarate transaminase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 2-oxoglutarate[c] + 1 3-hydroxy-L-kynurenine[c] <=> 1 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate[c] + 1 L-glutamate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
    • 9 reactions found over 17 reactions in the full pathway

Reconstruction information

External links





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