Difference between revisions of "DIHYDROFOLATESYNTH-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14266 RXN-14266] == * direction: ** REVERSIBLE * common name: ** 3-hydroxyisovaleryl-CoA hydrat...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** f...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14266 RXN-14266] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] ==
 
* direction:
 
* direction:
−
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** 3-hydroxyisovaleryl-CoA hydratase
+
** folylpolyglutamate_synthase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/4.2.1.17 EC-4.2.1.17]
+
** [http://enzyme.expasy.org/EC/6.3.2.12 EC-6.3.2.12]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[3-HYDROXY-ISOVALERYL-COA]][c] '''<=>''' 1 [[CPD-1083]][c] '''+''' 1 [[WATER]][c]
+
** 1 [[7-8-DIHYDROPTEROATE]][c] '''+''' 1 [[GLT]][c] '''+''' 1 [[ATP]][c] '''=>''' 1 [[DIHYDROFOLATE]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[ADP]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 3-hydroxyisovaleryl-CoA[c] '''<=>''' 1 (E)-2-methylcrotonoyl-CoA[c] '''+''' 1 H2O[c]
+
** 1 7,8-dihydropteroate[c] '''+''' 1 L-glutamate[c] '''+''' 1 ATP[c] '''=>''' 1 7,8-dihydrofolate monoglutamate[c] '''+''' 1 phosphate[c] '''+''' 1 H+[c] '''+''' 1 ADP[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Tiso_gene_6885]]
+
* Gene: [[Tiso_gene_15942]]
−
** [[pantograph]]-[[esiliculosus]]
+
** Source: [[annotation-in-silico_annotation]]
−
* [[Tiso_gene_16145]]
+
*** Assignment: AUTOMATED-NAME-MATCH
−
** [[pantograph]]-[[esiliculosus]]
+
* Gene: [[Tiso_gene_92]]
−
* [[Tiso_gene_14262]]
+
** Source: [[orthology-synechocystis]]
−
** [[pantograph]]-[[esiliculosus]]
+
−
* [[Tiso_gene_5857]]
+
−
** [[pantograph]]-[[esiliculosus]]
+
−
* [[Tiso_gene_14257]]
+
−
** [[pantograph]]-[[esiliculosus]]
+
 
== Pathways  ==
 
== Pathways  ==
 +
* [[PWY-6614]], tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6614 PWY-6614]
 +
** '''3''' reactions found over '''3''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[orthology]]:
+
* Category: [[orthology]]
−
** [[pantograph]]:
+
** Source: [[orthology-synechocystis]]
−
*** [[esiliculosus]]
+
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=31082 31082]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23584 23584]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R04137 R04137]
+
** [http://www.genome.jp/dbget-bin/www_bget?R02237 R02237]
−
{{#set: direction=REVERSIBLE}}
+
* UNIPROT:
−
{{#set: common name=3-hydroxyisovaleryl-CoA hydratase}}
+
** [http://www.uniprot.org/uniprot/Q9JVC6 Q9JVC6]
−
{{#set: ec number=EC-4.2.1.17}}
+
** [http://www.uniprot.org/uniprot/P43775 P43775]
−
{{#set: gene associated=Tiso_gene_6885|Tiso_gene_16145|Tiso_gene_14262|Tiso_gene_5857|Tiso_gene_14257}}
+
** [http://www.uniprot.org/uniprot/Q9PNK6 Q9PNK6]
−
{{#set: in pathway=}}
+
** [http://www.uniprot.org/uniprot/Q50990 Q50990]
−
{{#set: reconstruction category=orthology}}
+
** [http://www.uniprot.org/uniprot/P08192 P08192]
−
{{#set: reconstruction tool=pantograph}}
+
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: reconstruction source=esiliculosus}}
+
{{#set: common name=folylpolyglutamate_synthase}}
 +
{{#set: ec number=EC-6.3.2.12}}
 +
{{#set: gene associated=Tiso_gene_15942|Tiso_gene_92}}
 +
{{#set: in pathway=PWY-6614}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-synechocystis}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:22, 21 March 2018

Reaction DIHYDROFOLATESYNTH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • folylpolyglutamate_synthase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 7,8-dihydropteroate[c] + 1 L-glutamate[c] + 1 ATP[c] => 1 7,8-dihydrofolate monoglutamate[c] + 1 phosphate[c] + 1 H+[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6614, tetrahydrofolate biosynthesis: PWY-6614
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links





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