Difference between revisions of "CITSYN-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-11921 RXN-11921] == * direction: ** LEFT-TO-RIGHT * common name: ** 3-methylcrotonyl-CoA:acetyl...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=CITSYN-RXN CITSYN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** citrate_synthase * ec num...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-11921 RXN-11921] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=CITSYN-RXN CITSYN-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** 3-methylcrotonyl-CoA:acetyl-CoA C-acyltransferase
+
** citrate_synthase
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/2.3.1 EC-2.3.1]
+
** [http://enzyme.expasy.org/EC/2.3.3.16 EC-2.3.3.16]
 +
** [http://enzyme.expasy.org/EC/2.3.3.1 EC-2.3.3.1]
 
* Synonym(s):
 
* Synonym(s):
** 5-methyl-3-oxo-4-hexenoyl-CoA thiolase
+
** Condensing enzyme
 +
** citrate synthesis
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[CPD-12906]][c] '''+''' 1 [[CO-A]][c] '''=>''' 1 [[ACETYL-COA]][c] '''+''' 1 [[3-METHYL-CROTONYL-COA]][c]
+
** 1 [[WATER]][c] '''+''' 1 [[OXALACETIC_ACID]][c] '''+''' 1 [[ACETYL-COA]][c] '''=>''' 1 [[CIT]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c]
 
* With common name(s):
 
* With common name(s):
** 1 5-methyl-3-oxo-4-hexenoyl-CoA[c] '''+''' 1 coenzyme A[c] '''=>''' 1 acetyl-CoA[c] '''+''' 1 3-methylcrotonyl-CoA[c]
+
** 1 H2O[c] '''+''' 1 oxaloacetate[c] '''+''' 1 acetyl-CoA[c] '''=>''' 1 citrate[c] '''+''' 1 coenzyme A[c] '''+''' 1 H+[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[Tiso_gene_16181]]
+
* Gene: [[Tiso_gene_18030]]
** [[pantograph]]-[[athaliana]]
+
** Source: [[annotation-in-silico_annotation]]
** [[pantograph]]-[[esiliculosus]]
+
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_9601]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_9603]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_9602]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-6672]], cis-genanyl-CoA degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6672 PWY-6672]
+
* [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
** '''4''' reactions found over '''9''' reactions in the full pathway
+
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-5750]], itaconate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5750 PWY-5750]
 +
** '''3''' reactions found over '''4''' reactions in the full pathway
 +
* [[PWY-7124]], ethylene biosynthesis V (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7124 PWY-7124]
 +
** '''7''' reactions found over '''10''' reactions in the full pathway
 +
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
 +
** '''9''' reactions found over '''12''' reactions in the full pathway
 +
* [[PWY-6549]], L-glutamine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6549 PWY-6549]
 +
** '''6''' reactions found over '''9''' reactions in the full pathway
 +
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[GLYOXYLATE-BYPASS]], glyoxylate cycle: [http://metacyc.org/META/NEW-IMAGE?object=GLYOXYLATE-BYPASS GLYOXYLATE-BYPASS]
 +
** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
 +
** '''9''' reactions found over '''16''' reactions in the full pathway
 +
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
 +
** '''11''' reactions found over '''18''' reactions in the full pathway
 +
* [[REDCITCYC]], TCA cycle VIII (helicobacter): [http://metacyc.org/META/NEW-IMAGE?object=REDCITCYC REDCITCYC]
 +
** '''6''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-7254]], TCA cycle VII (acetate-producers): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7254 PWY-7254]
 +
** '''5''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
 +
** '''6''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
 +
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
 +
** '''7''' reactions found over '''10''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* Category: [[orthology]]
+
* Category: [[manual]]
** Source: [[orthology-athaliana]]
+
** Source: [[manual-primary_network]]
*** Tool: [[pantograph]]
+
* Category: [[annotation]]
** Source: [[orthology-esiliculosus]]
+
** Source: [[annotation-in-silico_annotation]]
*** Tool: [[pantograph]]
+
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16845 16845]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R08095 R08095]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00351 R00351]
 +
* PIR:
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A43936 A43936]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81200 A81200]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B81139 B81139]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64760 E64760]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=F86708 F86708]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=G69600 G69600]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=G81265 G81265]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I39506 I39506]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40044 I40044]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40380 I40380]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40717 I40717]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JQ1392 JQ1392]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PQ0046 PQ0046]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S41527 S41527]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S41563 S41563]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S42370 S42370]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S44316 S44316]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S52814 S52814]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T02390 T02390]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09334 T09334]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T44615 T44615]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKBY YKBY]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKBYC YKBYC]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKEC YKEC]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKMUM YKMUM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKMY YKMY]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKPG YKPG]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKPSCA YKPSCA]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKQPC YKQPC]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKRECP YKRECP]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=YKYT YKYT]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/Q9JRA5 Q9JRA5]
 +
** [http://www.uniprot.org/uniprot/Q9JQX0 Q9JQX0]
 +
** [http://www.uniprot.org/uniprot/P31660 P31660]
 +
** [http://www.uniprot.org/uniprot/Q9CHQ6 Q9CHQ6]
 +
** [http://www.uniprot.org/uniprot/P39120 P39120]
 +
** [http://www.uniprot.org/uniprot/Q9PLZ5 Q9PLZ5]
 +
** [http://www.uniprot.org/uniprot/P20902 P20902]
 +
** [http://www.uniprot.org/uniprot/P51033 P51033]
 +
** [http://www.uniprot.org/uniprot/P39119 P39119]
 +
** [http://www.uniprot.org/uniprot/P42457 P42457]
 +
** [http://www.uniprot.org/uniprot/P18789 P18789]
 +
** [http://www.uniprot.org/uniprot/P20903 P20903]
 +
** [http://www.uniprot.org/uniprot/P51038 P51038]
 +
** [http://www.uniprot.org/uniprot/P34085 P34085]
 +
** [http://www.uniprot.org/uniprot/P34575 P34575]
 +
** [http://www.uniprot.org/uniprot/Q43175 Q43175]
 +
** [http://www.uniprot.org/uniprot/P43635 P43635]
 +
** [http://www.uniprot.org/uniprot/O24259 O24259]
 +
** [http://www.uniprot.org/uniprot/O32705 O32705]
 +
** [http://www.uniprot.org/uniprot/P00890 P00890]
 +
** [http://www.uniprot.org/uniprot/P08679 P08679]
 +
** [http://www.uniprot.org/uniprot/P0ABH7 P0ABH7]
 +
** [http://www.uniprot.org/uniprot/Q47237 Q47237]
 +
** [http://www.uniprot.org/uniprot/P20115 P20115]
 +
** [http://www.uniprot.org/uniprot/P26491 P26491]
 +
** [http://www.uniprot.org/uniprot/P00889 P00889]
 +
** [http://www.uniprot.org/uniprot/P20901 P20901]
 +
** [http://www.uniprot.org/uniprot/P09948 P09948]
 +
** [http://www.uniprot.org/uniprot/P21553 P21553]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=3-methylcrotonyl-CoA:acetyl-CoA C-acyltransferase}}
+
{{#set: common name=citrate_synthase}}
{{#set: ec number=EC-2.3.1}}
+
{{#set: ec number=EC-2.3.3.16}}
{{#set: common name=5-methyl-3-oxo-4-hexenoyl-CoA thiolase}}
+
{{#set: ec number=EC-2.3.3.1}}
{{#set: gene associated=Tiso_gene_16181}}
+
{{#set: common name=Condensing enzyme|citrate synthesis}}
{{#set: in pathway=PWY-6672}}
+
{{#set: gene associated=Tiso_gene_18030|Tiso_gene_9601|Tiso_gene_9603|Tiso_gene_9602}}
{{#set: reconstruction category=orthology}}
+
{{#set: in pathway=PWY-5913|PWY-5750|PWY-7124|PWY-6969|PWY-6549|P105-PWY|GLYOXYLATE-BYPASS|FERMENTATION-PWY|PWY-6728|REDCITCYC|PWY-7254|PWY-5690|PWY66-398|TCA}}
{{#set: reconstruction source=orthology-athaliana|orthology-esiliculosus}}
+
{{#set: reconstruction category=manual|annotation}}
{{#set: reconstruction tool=pantograph}}
+
{{#set: reconstruction source=annotation-in-silico_annotation|manual-primary_network|annotation-experimental_annotation}}
 +
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 19:30, 21 March 2018

Reaction CITSYN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • citrate_synthase
  • ec number:
  • Synonym(s):
    • Condensing enzyme
    • citrate synthesis

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 H2O[c] + 1 oxaloacetate[c] + 1 acetyl-CoA[c] => 1 citrate[c] + 1 coenzyme A[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
    • 9 reactions found over 11 reactions in the full pathway
  • PWY-5750, itaconate biosynthesis: PWY-5750
    • 3 reactions found over 4 reactions in the full pathway
  • PWY-7124, ethylene biosynthesis V (engineered): PWY-7124
    • 7 reactions found over 10 reactions in the full pathway
  • PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
    • 9 reactions found over 12 reactions in the full pathway
  • PWY-6549, L-glutamine biosynthesis III: PWY-6549
    • 6 reactions found over 9 reactions in the full pathway
  • P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
    • 9 reactions found over 11 reactions in the full pathway
  • GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
    • 6 reactions found over 6 reactions in the full pathway
  • FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
    • 9 reactions found over 16 reactions in the full pathway
  • PWY-6728, methylaspartate cycle: PWY-6728
    • 11 reactions found over 18 reactions in the full pathway
  • REDCITCYC, TCA cycle VIII (helicobacter): REDCITCYC
    • 6 reactions found over 9 reactions in the full pathway
  • PWY-7254, TCA cycle VII (acetate-producers): PWY-7254
    • 5 reactions found over 9 reactions in the full pathway
  • PWY-5690, TCA cycle II (plants and fungi): PWY-5690
    • 6 reactions found over 9 reactions in the full pathway
  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 10 reactions found over 11 reactions in the full pathway
  • TCA, TCA cycle I (prokaryotic): TCA
    • 7 reactions found over 10 reactions in the full pathway

Reconstruction information

External links