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| − | [[Category:Reaction]] | + | [[Category:Metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALDEHYDROG-RXN 3-ISOPROPYLMALDEHYDROG-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Charged-SEC-tRNAs Charged-SEC-tRNAs] == |
| − | * direction:
| + | |
| − | ** REVERSIBLE
| + | |
| | * common name: | | * common name: |
| − | ** 3-isopropylmalate dehydrogenase | + | ** an L-selenocysteinyl-[tRNAsec] |
| | * Synonym(s): | | * Synonym(s): |
| − | ** β-isopropylmalic enzyme
| |
| − | ** threo-Ds-3-isopropylmalate dehydrogenase
| |
| | | | |
| − | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
| − | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
| − | ** 1 [[2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[CPD-7100]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[NADH]][c]
| + | * [[RXN-10039]] |
| − | * With common name(s):
| + | == Reaction(s) of unknown directionality == |
| − | ** 1 (2R,3S)-3-isopropylmalate[c] '''+''' 1 NAD+[c] '''<=>''' 1 (2S)-2-isopropyl-3-oxosuccinate[c] '''+''' 1 H+[c] '''+''' 1 NADH[c]
| + | |
| − | | + | |
| − | == Genes associated with this reaction == | + | |
| − | Genes have been associated with this reaction based on different elements listed below.
| + | |
| − | * [[Tiso_gene_2920]] | + | |
| − | ** EXPERIMENTAL_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | ** [[pantograph]]-[[athaliana]]
| + | |
| − | ** [[pantograph]]-[[synechocystis]]
| + | |
| − | ** [[pantograph]]-[[esiliculosus]]
| + | |
| − | == Pathways == | + | |
| − | * [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
| + | |
| − | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
| − | * [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
| + | |
| − | ** '''6''' reactions found over '''7''' reactions in the full pathway
| + | |
| − | == Reconstruction information == | + | |
| − | * [[orthology]]:
| + | |
| − | ** [[pantograph]]:
| + | |
| − | *** [[synechocystis]]
| + | |
| − | *** [[esiliculosus]]
| + | |
| − | *** [[athaliana]]
| + | |
| − | * [[annotation]]:
| + | |
| − | ** [[pathwaytools]]:
| + | |
| − | *** [[experimental_annotation]]
| + | |
| | == External links == | | == External links == |
| − | * RHEA:
| + | {{#set: common name=an L-selenocysteinyl-[tRNAsec]}} |
| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10892 10892]
| + | {{#set: produced by=RXN-10039}} |
| − | * LIGAND-RXN:
| + | |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?R04426 R04426]
| + | |
| − | * UNIPROT:
| + | |
| − | ** [http://www.uniprot.org/uniprot/P05644 P05644]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P05645 P05645]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q01987 Q01987]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q00412 Q00412]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P08791 P08791]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P30125 P30125]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9PLW0 Q9PLW0]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O66607 O66607]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P12010 P12010]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P04173 P04173]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q5SIY4 Q5SIY4]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P24098 P24098]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9JU79 Q9JU79]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P43860 P43860]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P41019 P41019]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P54354 P54354]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q56268 Q56268]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P29102 P29102]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P37412 P37412]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P23390 P23390]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P29696 P29696]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P41766 P41766]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q02143 Q02143]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P34733 P34733]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P50180 P50180]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q12591 Q12591]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q12590 Q12590]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q12592 Q12592]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P07139 P07139]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P41926 P41926]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P48012 P48012]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P87256 P87256]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P87257 P87257]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P73960 P73960]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O86504 O86504]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O85837 O85837]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P18869 P18869]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P34738 P34738]
| + | |
| − | {{#set: direction=REVERSIBLE}}
| + | |
| − | {{#set: common name=3-isopropylmalate dehydrogenase}} | + | |
| − | {{#set: common name=β-isopropylmalic enzyme|threo-Ds-3-isopropylmalate dehydrogenase}}
| + | |
| − | {{#set: gene associated=Tiso_gene_2920}} | + | |
| − | {{#set: in pathway=LEUSYN-PWY|PWY-6871}}
| + | |
| − | {{#set: reconstruction category=orthology}}
| + | |
| − | {{#set: reconstruction tool=pantograph}}
| + | |
| − | {{#set: reconstruction source=synechocystis|esiliculosus|athaliana}}
| + | |
| − | {{#set: reconstruction category=annotation}}
| + | |
| − | {{#set: reconstruction tool=pathwaytools}}
| + | |
| − | {{#set: reconstruction source=experimental_annotation}}
| + | |
