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− | [[Category:Reaction]] | + | [[Category:Gene]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALISOM-RXN 3-ISOPROPYLMALISOM-RXN] == | + | == Gene Tiso_gene_13522 == |
− | * direction: | + | * right end position: |
− | ** REVERSIBLE | + | ** 6243 |
− | * common name: | + | * transcription direction: |
− | ** 3-isopropylmalate dehydratase | + | ** POSITIVE |
− | ** ORF | + | * left end position: |
| + | ** 5175 |
| + | * centisome position: |
| + | ** 82.87957 |
| * Synonym(s): | | * Synonym(s): |
− | ** (2R,3S)-3-isopropylmalate hydro-lyase
| |
− | ** β-isopropylmalate dehydratase
| |
− | ** α-isopropylmalate isomerase
| |
− | ** 3-isopropylmalate hydro-lyase
| |
| | | |
− | == Reaction Formula == | + | == Reactions associated == |
− | * With identifiers:
| + | * Reaction: [[ATPASE-RXN]] |
− | ** 1 [[WATER]][c] '''+''' 1 [[CPD-9451]][c] '''<=>''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c]
| + | |
− | * With common name(s):
| + | |
− | ** 1 H2O[c] '''+''' 1 2-isopropylmaleate[c] '''<=>''' 1 (2S)-2-isopropylmalate[c]
| + | |
− | | + | |
− | == Genes associated with this reaction ==
| + | |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * Gene: [[Tiso_gene_12778]] | + | |
− | ** Source: [[annotation-in-silico_annotation]]
| + | |
− | *** Assignment: EC-NUMBER
| + | |
− | ** Source: [[annotation-experimental_annotation]]
| + | |
− | *** Assignment: EC-NUMBER
| + | |
− | ** Source: [[orthology-athaliana]]
| + | |
− | ** Source: [[orthology-esiliculosus]]
| + | |
− | == Pathways ==
| + | |
− | * [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
| + | |
− | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
− | * [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
| + | |
− | ** '''6''' reactions found over '''7''' reactions in the full pathway
| + | |
− | == Reconstruction information ==
| + | |
− | * Category: [[orthology]]
| + | |
− | ** Source: [[orthology-athaliana]]
| + | |
− | *** Tool: [[pantograph]]
| + | |
− | ** Source: [[orthology-esiliculosus]]
| + | |
− | *** Tool: [[pantograph]]
| + | |
− | * Category: [[annotation]]
| + | |
| ** Source: [[annotation-in-silico_annotation]] | | ** Source: [[annotation-in-silico_annotation]] |
− | *** Tool: [[pathwaytools]] | + | *** Assignment: ec-number |
− | ** Source: [[annotation-experimental_annotation]]
| + | == Pathways associated == |
− | *** Tool: [[pathwaytools]]
| + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: right end position=6243}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16293 16293]
| + | {{#set: transcription direction=POSITIVE}} |
− | * LIGAND-RXN:
| + | {{#set: left end position=5175}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R03968 R03968]
| + | {{#set: centisome position=82.87957 }} |
− | * UNIPROT:
| + | {{#set: reaction associated=ATPASE-RXN}} |
− | ** [http://www.uniprot.org/uniprot/Q9PLW1 Q9PLW1]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JU82 Q9JU82]
| + | |
− | ** [http://www.uniprot.org/uniprot/P80858 P80858]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9UZ07 Q9UZ07]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JU81 Q9JU81]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q58673 Q58673]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q02144 Q02144]
| + | |
− | ** [http://www.uniprot.org/uniprot/P44968 P44968]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q58667 Q58667]
| + | |
− | ** [http://www.uniprot.org/uniprot/P44438 P44438]
| + | |
− | ** [http://www.uniprot.org/uniprot/P0A6A6 P0A6A6]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PLW2 Q9PLW2]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q44022 Q44022]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q44023 Q44023]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q44427 Q44427]
| + | |
− | ** [http://www.uniprot.org/uniprot/P17279 P17279]
| + | |
− | ** [http://www.uniprot.org/uniprot/P04787 P04787]
| + | |
− | ** [http://www.uniprot.org/uniprot/P15717 P15717]
| + | |
− | ** [http://www.uniprot.org/uniprot/P18250 P18250]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q02142 Q02142]
| + | |
− | ** [http://www.uniprot.org/uniprot/P30126 P30126]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50181 P50181]
| + | |
− | ** [http://www.uniprot.org/uniprot/P07264 P07264]
| + | |
− | ** [http://www.uniprot.org/uniprot/P74207 P74207]
| + | |
− | ** [http://www.uniprot.org/uniprot/O86534 O86534]
| + | |
− | ** [http://www.uniprot.org/uniprot/O86535 O86535]
| + | |
− | {{#set: direction=REVERSIBLE}} | + | |
− | {{#set: common name=3-isopropylmalate dehydratase}} | + | |
− | {{#set: common name=ORF}} | + | |
− | {{#set: common name=(2R,3S)-3-isopropylmalate hydro-lyase|β-isopropylmalate dehydratase|α-isopropylmalate isomerase|3-isopropylmalate hydro-lyase}} | + | |
− | {{#set: gene associated=Tiso_gene_12778}} | + | |
− | {{#set: in pathway=LEUSYN-PWY|PWY-6871}}
| + | |
− | {{#set: reconstruction category=orthology|annotation}}
| + | |
− | {{#set: reconstruction source=annotation-in-silico_annotation|orthology-athaliana|annotation-experimental_annotation|orthology-esiliculosus}}
| + | |
− | {{#set: reconstruction tool=pantograph|pathwaytools}}
| + | |