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| − | [[Category:Reaction]] | + | [[Category:Metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-ISOPROPYLMALISOM-RXN 3-ISOPROPYLMALISOM-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Glutamine-synthetase-adenylyl-Tyr Glutamine-synthetase-adenylyl-Tyr] == |
| − | * direction:
| + | |
| − | ** REVERSIBLE
| + | |
| | * common name: | | * common name: |
| − | ** 3-isopropylmalate dehydratase | + | ** a [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine |
| − | ** ORF
| + | |
| | * Synonym(s): | | * Synonym(s): |
| − | ** (2R,3S)-3-isopropylmalate hydro-lyase
| |
| − | ** β-isopropylmalate dehydratase
| |
| − | ** α-isopropylmalate isomerase
| |
| − | ** 3-isopropylmalate hydro-lyase
| |
| | | | |
| − | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
| − | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
| − | ** 1 [[CPD-9451]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c]
| + | * [[GSADENYLATION-RXN]] |
| − | * With common name(s):
| + | == Reaction(s) of unknown directionality == |
| − | ** 1 2-isopropylmaleate[c] '''+''' 1 H2O[c] '''<=>''' 1 (2S)-2-isopropylmalate[c]
| + | |
| − | | + | |
| − | == Genes associated with this reaction == | + | |
| − | Genes have been associated with this reaction based on different elements listed below.
| + | |
| − | * [[Tiso_gene_12778]] | + | |
| − | ** IN-SILICO_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | ** EXPERIMENTAL_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | ** [[pantograph]]-[[athaliana]]
| + | |
| − | ** [[pantograph]]-[[esiliculosus]]
| + | |
| − | == Pathways == | + | |
| − | * [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
| + | |
| − | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
| − | * [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
| + | |
| − | ** '''6''' reactions found over '''7''' reactions in the full pathway
| + | |
| − | == Reconstruction information == | + | |
| − | * [[orthology]]:
| + | |
| − | ** [[pantograph]]:
| + | |
| − | *** [[esiliculosus]]
| + | |
| − | *** [[athaliana]]
| + | |
| − | * [[annotation]]:
| + | |
| − | ** [[pathwaytools]]:
| + | |
| − | *** [[experimental_annotation]]
| + | |
| − | *** [[in-silico_annotation]]
| + | |
| | == External links == | | == External links == |
| − | * RHEA:
| + | {{#set: common name=a [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine}} |
| − | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16293 16293]
| + | {{#set: produced by=GSADENYLATION-RXN}} |
| − | * LIGAND-RXN:
| + | |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?R03968 R03968]
| + | |
| − | * UNIPROT:
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9PLW1 Q9PLW1]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9JU82 Q9JU82]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P80858 P80858]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9UZ07 Q9UZ07]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9JU81 Q9JU81]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q58673 Q58673]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q02144 Q02144]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P44968 P44968]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q58667 Q58667]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P44438 P44438]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P0A6A6 P0A6A6]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9PLW2 Q9PLW2]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q44022 Q44022]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q44023 Q44023]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q44427 Q44427]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P17279 P17279]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P04787 P04787]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P15717 P15717]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P18250 P18250]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q02142 Q02142]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P30126 P30126]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P50181 P50181]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P07264 P07264]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P74207 P74207]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O86534 O86534]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O86535 O86535]
| + | |
| − | {{#set: direction=REVERSIBLE}}
| + | |
| − | {{#set: common name=3-isopropylmalate dehydratase}} | + | |
| − | {{#set: common name=ORF}}
| + | |
| − | {{#set: common name=(2R,3S)-3-isopropylmalate hydro-lyase|β-isopropylmalate dehydratase|α-isopropylmalate isomerase|3-isopropylmalate hydro-lyase}}
| + | |
| − | {{#set: gene associated=Tiso_gene_12778}} | + | |
| − | {{#set: in pathway=LEUSYN-PWY|PWY-6871}}
| + | |
| − | {{#set: reconstruction category=orthology}}
| + | |
| − | {{#set: reconstruction tool=pantograph}}
| + | |
| − | {{#set: reconstruction source=esiliculosus|athaliana}}
| + | |
| − | {{#set: reconstruction category=annotation}}
| + | |
| − | {{#set: reconstruction tool=pathwaytools}}
| + | |
| − | {{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
| + | |
