Difference between revisions of "RXN66-12"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD0-2117 CPD0-2117] == * smiles: ** CCCCCCCCCCCCCC=CC(=O)SCCNC(=O)CCNC(C(O)C(C)(C)COP([O-])(=O...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN66-12 RXN66-12] == * direction: ** LEFT-TO-RIGHT * common name: ** 4,4-dimethyl-14α-hydrox...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD0-2117 CPD0-2117] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN66-12 RXN66-12] ==
* smiles:
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* direction:
** CCCCCCCCCCCCCC=CC(=O)SCCNC(=O)CCNC(C(O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OCC1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2(C(N)=NC=NC=23))))=O
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** LEFT-TO-RIGHT
* inchi key:
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** InChIKey=JUPAQFRKPHPXLD-MSHHSVQMSA-J
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* common name:
 
* common name:
** trans-hexadec-2-enoyl-CoA
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** 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase
* molecular weight:
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** 999.899   
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* Synonym(s):
 
* Synonym(s):
** trans-2-hexadecenoyl-CoA
 
** (2E)-hexadecenoyl-CoA
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
== Reaction(s) known to produce the compound ==
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* With identifiers:
* [[RXN-16540]]
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** 1 [[OXYGEN-MOLECULE]][c] '''+''' 1 [[CPD-8607]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[PROTON]][c] '''=>''' 2 [[WATER]][c] '''+''' 1 [[NADP]][c] '''+''' 1 [[CPD-8608]][c]
* [[ACOA160or]]
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* With common name(s):
== Reaction(s) of unknown directionality ==
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** 1 oxygen[c] '''+''' 1 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol[c] '''+''' 1 NADPH[c] '''+''' 1 H+[c] '''=>''' 2 H2O[c] '''+''' 1 NADP+[c] '''+''' 1 4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_8263]]
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** Source: [[orthology-esiliculosus]]
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== Pathways  ==
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* [[PWY66-3]], cholesterol biosynthesis II (via 24,25-dihydrolanosterol): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-3 PWY66-3]
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** '''8''' reactions found over '''22''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-esiliculosus]]
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*** Tool: [[pantograph]]
 
== External links  ==
 
== External links  ==
* BIGG : hdd2coa
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{{#set: direction=LEFT-TO-RIGHT}}
* PUBCHEM:
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{{#set: common name=4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase}}
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=46173176 46173176]
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{{#set: gene associated=Tiso_gene_8263}}
* HMDB : HMDB03945
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{{#set: in pathway=PWY66-3}}
* LIGAND-CPD:
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{{#set: reconstruction category=orthology}}
** [http://www.genome.jp/dbget-bin/www_bget?C05272 C05272]
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{{#set: reconstruction source=orthology-esiliculosus}}
* CHEBI:
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{{#set: reconstruction tool=pantograph}}
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=61526 61526]
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* METABOLIGHTS : MTBLC61526
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{{#set: smiles=CCCCCCCCCCCCCC=CC(=O)SCCNC(=O)CCNC(C(O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OCC1(C(OP(=O)([O-])[O-])C(O)C(O1)N3(C=NC2(C(N)=NC=NC=23))))=O}}
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{{#set: inchi key=InChIKey=JUPAQFRKPHPXLD-MSHHSVQMSA-J}}
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{{#set: common name=trans-hexadec-2-enoyl-CoA}}
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{{#set: molecular weight=999.899    }}
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{{#set: common name=trans-2-hexadecenoyl-CoA|(2E)-hexadecenoyl-CoA}}
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{{#set: produced by=RXN-16540|ACOA160or}}
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Latest revision as of 19:57, 21 March 2018

Reaction RXN66-12

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol 14-dehydrogenase
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 oxygen[c] + 1 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol[c] + 1 NADPH[c] + 1 H+[c] => 2 H2O[c] + 1 NADP+[c] + 1 4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-3, cholesterol biosynthesis II (via 24,25-dihydrolanosterol): PWY66-3
    • 8 reactions found over 22 reactions in the full pathway

Reconstruction information

External links