Difference between revisions of "GLYOHMETRANS-RXN"

From metabolic_network
Jump to: navigation, search
(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HOMO-CIS-ACONITATE HOMO-CIS-ACONITATE] == * smiles: ** C(=O)([O-])C=C(CCC([O-])=O)C(=O)[O-] * i...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYOHMETRANS-RXN GLYOHMETRANS-RXN] == * direction: ** REVERSIBLE * common name: ** serine_hydroxyme...")
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
−
[[Category:Metabolite]]
+
[[Category:Reaction]]
−
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HOMO-CIS-ACONITATE HOMO-CIS-ACONITATE] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYOHMETRANS-RXN GLYOHMETRANS-RXN] ==
−
* smiles:
+
* direction:
−
** C(=O)([O-])C=C(CCC([O-])=O)C(=O)[O-]
+
** REVERSIBLE
−
* inchi key:
+
−
** InChIKey=BJYPZFUWWJSAKC-ARJAWSKDSA-K
+
 
* common name:
 
* common name:
−
** cis-homoaconitate
+
** serine_hydroxymethyltransferase
−
* molecular weight:
+
** serine_cytosolic-like_isoform_1
−
** 185.113   
+
** serine_hydroxymethyltransferase_mitochondrial
 +
** ORF
 +
* ec number:
 +
** [http://enzyme.expasy.org/EC/2.1.2.1 EC-2.1.2.1]
 
* Synonym(s):
 
* Synonym(s):
−
** 3-carboxyhex-2-enedioate
 
−
** (Z)-but-1-ene-1,2,4-tricarboxylate
 
−
** homo-cis-aconitate
 
−
** (Z)-1,2,4-but-1-enetricarboxylic acid
 
  
−
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
−
== Reaction(s) known to produce the compound ==
+
* With identifiers:
−
== Reaction(s) of unknown directionality ==
+
** 1 [[THF-GLU-N]][c] '''+''' 1 [[SER]][c] '''<=>''' 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[WATER]][c] '''+''' 1 [[GLY]][c]
−
* [[HOMOACONITATE-HYDRATASE-RXN]]
+
* With common name(s):
 +
** 1 a tetrahydrofolate[c] '''+''' 1 L-serine[c] '''<=>''' 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 H2O[c] '''+''' 1 glycine[c]
 +
 
 +
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[Tiso_gene_16153]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_7776]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_18652]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
* Gene: [[Tiso_gene_16154]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
== Pathways  ==
 +
* [[PWY-2161]], folate polyglutamylation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2161 PWY-2161]
 +
** '''5''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-1622]], formaldehyde assimilation I (serine pathway): [http://metacyc.org/META/NEW-IMAGE?object=PWY-1622 PWY-1622]
 +
** '''5''' reactions found over '''13''' reactions in the full pathway
 +
* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
 +
** '''7''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-3661]], glycine betaine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3661 PWY-3661]
 +
** '''4''' reactions found over '''7''' reactions in the full pathway
 +
* [[GLYSYN-PWY]], glycine biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=GLYSYN-PWY GLYSYN-PWY]
 +
** '''1''' reactions found over '''1''' reactions in the full pathway
 +
* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
 +
** '''7''' reactions found over '''24''' reactions in the full pathway
 +
* [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201]
 +
** '''7''' reactions found over '''12''' reactions in the full pathway
 +
* [[PWY-181]], photorespiration: [http://metacyc.org/META/NEW-IMAGE?object=PWY-181 PWY-181]
 +
** '''5''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-3661-1]], glycine betaine degradation II (mammalian): [http://metacyc.org/META/NEW-IMAGE?object=PWY-3661-1 PWY-3661-1]
 +
** '''3''' reactions found over '''4''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[manual]]
 +
** Source: [[manual-primary_network]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* PUBCHEM:
+
* RHEA:
−
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=21158450 21158450]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15481 15481]
−
* CHEMSPIDER:
+
* LIGAND-RXN:
−
** [http://www.chemspider.com/Chemical-Structure.20117984.html 20117984]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00945 R00945]
−
* CHEBI:
+
* UNIPROT:
−
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58174 58174]
+
** [http://www.uniprot.org/uniprot/P35623 P35623]
−
* LIGAND-CPD:
+
** [http://www.uniprot.org/uniprot/P34898 P34898]
−
** [http://www.genome.jp/dbget-bin/www_bget?C04002 C04002]
+
** [http://www.uniprot.org/uniprot/P34899 P34899]
−
{{#set: smiles=C(=O)([O-])C=C(CCC([O-])=O)C(=O)[O-]}}
+
** [http://www.uniprot.org/uniprot/P34896 P34896]
−
{{#set: inchi key=InChIKey=BJYPZFUWWJSAKC-ARJAWSKDSA-K}}
+
** [http://www.uniprot.org/uniprot/Q9CHW7 Q9CHW7]
−
{{#set: common name=cis-homoaconitate}}
+
** [http://www.uniprot.org/uniprot/P34897 P34897]
−
{{#set: molecular weight=185.113    }}
+
** [http://www.uniprot.org/uniprot/P0A2E1 P0A2E1]
−
{{#set: common name=3-carboxyhex-2-enedioate|(Z)-but-1-ene-1,2,4-tricarboxylate|homo-cis-aconitate|(Z)-1,2,4-but-1-enetricarboxylic acid}}
+
** [http://www.uniprot.org/uniprot/O23254 O23254]
−
{{#set: consumed or produced by=HOMOACONITATE-HYDRATASE-RXN}}
+
** [http://www.uniprot.org/uniprot/O53441 O53441]
 +
** [http://www.uniprot.org/uniprot/O08370 O08370]
 +
** [http://www.uniprot.org/uniprot/P43844 P43844]
 +
** [http://www.uniprot.org/uniprot/Q58992 Q58992]
 +
** [http://www.uniprot.org/uniprot/O66776 O66776]
 +
** [http://www.uniprot.org/uniprot/Q9XAY7 Q9XAY7]
 +
** [http://www.uniprot.org/uniprot/P47634 P47634]
 +
** [http://www.uniprot.org/uniprot/Q9WZH9 Q9WZH9]
 +
** [http://www.uniprot.org/uniprot/P56089 P56089]
 +
** [http://www.uniprot.org/uniprot/O53615 O53615]
 +
** [http://www.uniprot.org/uniprot/O83349 O83349]
 +
** [http://www.uniprot.org/uniprot/Q9ZMP7 Q9ZMP7]
 +
** [http://www.uniprot.org/uniprot/O51547 O51547]
 +
** [http://www.uniprot.org/uniprot/O84439 O84439]
 +
** [http://www.uniprot.org/uniprot/P24531 P24531]
 +
** [http://www.uniprot.org/uniprot/P39148 P39148]
 +
** [http://www.uniprot.org/uniprot/P24060 P24060]
 +
** [http://www.uniprot.org/uniprot/P37292 P37292]
 +
** [http://www.uniprot.org/uniprot/P34895 P34895]
 +
** [http://www.uniprot.org/uniprot/P34894 P34894]
 +
** [http://www.uniprot.org/uniprot/P49357 P49357]
 +
** [http://www.uniprot.org/uniprot/P49358 P49358]
 +
** [http://www.uniprot.org/uniprot/P50433 P50433]
 +
** [http://www.uniprot.org/uniprot/P37291 P37291]
 +
** [http://www.uniprot.org/uniprot/P78011 P78011]
 +
** [http://www.uniprot.org/uniprot/P77962 P77962]
 +
** [http://www.uniprot.org/uniprot/Q9SVM4 Q9SVM4]
 +
** [http://www.uniprot.org/uniprot/Q9SUU0 Q9SUU0]
 +
** [http://www.uniprot.org/uniprot/Q9SZJ5 Q9SZJ5]
 +
** [http://www.uniprot.org/uniprot/O23984 O23984]
 +
** [http://www.uniprot.org/uniprot/P0A825 P0A825]
 +
** [http://www.uniprot.org/uniprot/P07511 P07511]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=serine_hydroxymethyltransferase}}
 +
{{#set: common name=serine_cytosolic-like_isoform_1}}
 +
{{#set: common name=serine_hydroxymethyltransferase_mitochondrial}}
 +
{{#set: common name=ORF}}
 +
{{#set: ec number=EC-2.1.2.1}}
 +
{{#set: gene associated=Tiso_gene_16153|Tiso_gene_7776|Tiso_gene_18652|Tiso_gene_16154}}
 +
{{#set: in pathway=PWY-2161|PWY-1622|PWY-3841|1CMET2-PWY|PWY-3661|GLYSYN-PWY|PWY-5497|PWY-2201|PWY-181|PWY-3661-1}}
 +
{{#set: reconstruction category=orthology|manual|annotation}}
 +
{{#set: reconstruction source=annotation-in-silico_annotation|manual-primary_network|annotation-experimental_annotation|orthology-esiliculosus}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 21:02, 21 March 2018

Reaction GLYOHMETRANS-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • serine_hydroxymethyltransferase
    • serine_cytosolic-like_isoform_1
    • serine_hydroxymethyltransferase_mitochondrial
    • ORF
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 a tetrahydrofolate[c] + 1 L-serine[c] <=> 1 a 5,10-methylene-tetrahydrofolate[c] + 1 H2O[c] + 1 glycine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-2161, folate polyglutamylation: PWY-2161
    • 5 reactions found over 5 reactions in the full pathway
  • PWY-1622, formaldehyde assimilation I (serine pathway): PWY-1622
    • 5 reactions found over 13 reactions in the full pathway
  • PWY-3841, folate transformations II: PWY-3841
    • 9 reactions found over 11 reactions in the full pathway
  • 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
    • 7 reactions found over 9 reactions in the full pathway
  • PWY-3661, glycine betaine degradation I: PWY-3661
    • 4 reactions found over 7 reactions in the full pathway
  • GLYSYN-PWY, glycine biosynthesis I: GLYSYN-PWY
    • 1 reactions found over 1 reactions in the full pathway
  • PWY-5497, purine nucleobases degradation II (anaerobic): PWY-5497
    • 7 reactions found over 24 reactions in the full pathway
  • PWY-2201, folate transformations I: PWY-2201
    • 7 reactions found over 12 reactions in the full pathway
  • PWY-181, photorespiration: PWY-181
    • 5 reactions found over 9 reactions in the full pathway
  • PWY-3661-1, glycine betaine degradation II (mammalian): PWY-3661-1
    • 3 reactions found over 4 reactions in the full pathway

Reconstruction information

External links






Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=GLYOHMETRANS-RXN&oldid=45422"