Difference between revisions of "BRANCHED-CHAINAMINOTRANSFERILEU-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=2-ALPHA-HYDROXYETHYL-THPP 2-ALPHA-HYDROXYETHYL-THPP] == * smiles: ** CC2(=C(SC(C(C)O)=[N+](CC1(...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=BRANCHED-CHAINAMINOTRANSFERILEU-RXN BRANCHED-CHAINAMINOTRANSFERILEU-RXN] == * direction: ** REVERSI...")
 
(2 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=2-ALPHA-HYDROXYETHYL-THPP 2-ALPHA-HYDROXYETHYL-THPP] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=BRANCHED-CHAINAMINOTRANSFERILEU-RXN BRANCHED-CHAINAMINOTRANSFERILEU-RXN] ==
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* smiles:
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* direction:
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** CC2(=C(SC(C(C)O)=[N+](CC1(C=NC(C)=NC(N)=1))2)CCOP(=O)([O-])OP(=O)([O-])[O-])
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** REVERSIBLE
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* inchi key:
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** InChIKey=RRUVJGASJONMDY-UHFFFAOYSA-L
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* common name:
 
* common name:
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** 2-(α-hydroxyethyl)thiamine diphosphate
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** branched-chain_amino_acid_aminotransferase
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* molecular weight:
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* ec number:
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** 466.341   
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** [http://enzyme.expasy.org/EC/2.6.1.42 EC-2.6.1.42]
 
* Synonym(s):
 
* Synonym(s):
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** 2-(α-hydroxyethyl)-TPP
 
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** 2-(α-hydroxyethyl)-ThPP
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[RXN-12508]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[ILE]][c] '''+''' 1 [[2-KETOGLUTARATE]][c] '''<=>''' 1 [[GLT]][c] '''+''' 1 [[2-KETO-3-METHYL-VALERATE]][c]
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* [[RXN-12583]]
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* With common name(s):
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== Reaction(s) of unknown directionality ==
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** 1 L-isoleucine[c] '''+''' 1 2-oxoglutarate[c] '''<=>''' 1 L-glutamate[c] '''+''' 1 (S)-3-methyl-2-oxopentanoate[c]
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* [[RXN-14037]]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_14984]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-athaliana]]
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** Source: [[orthology-synechocystis]]
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** Source: [[orthology-esiliculosus]]
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** Source: [[orthology-creinhardtii]]
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* Gene: [[Tiso_gene_18403]]
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** Source: [[orthology-synechocystis]]
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* Gene: [[Tiso_gene_17748]]
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** Source: [[orthology-athaliana]]
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** Source: [[orthology-esiliculosus]]
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== Pathways  ==
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* [[ILEUSYN-PWY]], L-isoleucine biosynthesis I (from threonine): [http://metacyc.org/META/NEW-IMAGE?object=ILEUSYN-PWY ILEUSYN-PWY]
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** '''7''' reactions found over '''7''' reactions in the full pathway
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* [[ILEUDEG-PWY]], L-isoleucine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=ILEUDEG-PWY ILEUDEG-PWY]
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** '''4''' reactions found over '''6''' reactions in the full pathway
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* [[PWY-5108]], L-isoleucine biosynthesis V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5108 PWY-5108]
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** '''2''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-5103]], L-isoleucine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5103 PWY-5103]
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** '''4''' reactions found over '''7''' reactions in the full pathway
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* [[PWY-5101]], L-isoleucine biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5101 PWY-5101]
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** '''5''' reactions found over '''8''' reactions in the full pathway
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* [[PWY-5078]], L-isoleucine degradation II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5078 PWY-5078]
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** '''2''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-5104]], L-isoleucine biosynthesis IV: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5104 PWY-5104]
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** '''3''' reactions found over '''6''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-athaliana]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-creinhardtii]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-synechocystis]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-esiliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[manual]]
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** Source: [[manual-primary_network]]
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* Category: [[annotation]]
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** Source: [[annotation-experimental_annotation]]
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*** Tool: [[pathwaytools]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* RHEA:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=46878487 46878487]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24801 24801]
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* CHEBI:
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* LIGAND-RXN:
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58939 58939]
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** [http://www.genome.jp/dbget-bin/www_bget?R02199 R02199]
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{{#set: smiles=CC2(=C(SC(C(C)O)=[N+](CC1(C=NC(C)=NC(N)=1))2)CCOP(=O)([O-])OP(=O)([O-])[O-])}}
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* UNIPROT:
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{{#set: inchi key=InChIKey=RRUVJGASJONMDY-UHFFFAOYSA-L}}
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** [http://www.uniprot.org/uniprot/Q9PIM6 Q9PIM6]
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{{#set: common name=2-(&alpha;-hydroxyethyl)thiamine diphosphate}}
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** [http://www.uniprot.org/uniprot/P38891 P38891]
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{{#set: molecular weight=466.341    }}
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** [http://www.uniprot.org/uniprot/P47176 P47176]
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{{#set: common name=2-(&alpha;-hydroxyethyl)-TPP|2-(&alpha;-hydroxyethyl)-ThPP}}
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** [http://www.uniprot.org/uniprot/O86505 O86505]
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{{#set: consumed by=RXN-12508}}
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** [http://www.uniprot.org/uniprot/O14370 O14370]
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{{#set: produced by=RXN-12583}}
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** [http://www.uniprot.org/uniprot/O32954 O32954]
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{{#set: consumed or produced by=RXN-14037}}
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** [http://www.uniprot.org/uniprot/P0AB80 P0AB80]
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{{#set: direction=REVERSIBLE}}
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{{#set: common name=branched-chain_amino_acid_aminotransferase}}
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{{#set: ec number=EC-2.6.1.42}}
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{{#set: gene associated=Tiso_gene_14984|Tiso_gene_18403|Tiso_gene_17748}}
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{{#set: in pathway=ILEUSYN-PWY|ILEUDEG-PWY|PWY-5108|PWY-5103|PWY-5101|PWY-5078|PWY-5104}}
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{{#set: reconstruction category=orthology|manual|annotation}}
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{{#set: reconstruction source=annotation-experimental_annotation|orthology-esiliculosus|annotation-in-silico_annotation|orthology-athaliana|orthology-synechocystis|manual-primary_network|orthology-creinhardtii}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 21:06, 21 March 2018

Reaction BRANCHED-CHAINAMINOTRANSFERILEU-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • branched-chain_amino_acid_aminotransferase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine): ILEUSYN-PWY
    • 7 reactions found over 7 reactions in the full pathway
  • ILEUDEG-PWY, L-isoleucine degradation I: ILEUDEG-PWY
    • 4 reactions found over 6 reactions in the full pathway
  • PWY-5108, L-isoleucine biosynthesis V: PWY-5108
    • 2 reactions found over 3 reactions in the full pathway
  • PWY-5103, L-isoleucine biosynthesis III: PWY-5103
    • 4 reactions found over 7 reactions in the full pathway
  • PWY-5101, L-isoleucine biosynthesis II: PWY-5101
    • 5 reactions found over 8 reactions in the full pathway
  • PWY-5078, L-isoleucine degradation II: PWY-5078
    • 2 reactions found over 3 reactions in the full pathway
  • PWY-5104, L-isoleucine biosynthesis IV: PWY-5104
    • 3 reactions found over 6 reactions in the full pathway

Reconstruction information

External links





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