Difference between revisions of "THYROXINE-DEIODINASE-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=UDPKIN-RXN UDPKIN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** ORF ** nucleoside_diphosp...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYROXINE-DEIODINASE-RXN THYROXINE-DEIODINASE-RXN] == * direction: ** LEFT-TO-RIGHT * common name:...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=UDPKIN-RXN UDPKIN-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYROXINE-DEIODINASE-RXN THYROXINE-DEIODINASE-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** ORF
+
** type_i_iodothyronine_deiodinase
−
** nucleoside_diphosphate_kinase
+
−
** adenylate_kinase_domain-containing_protein_1
+
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/2.7.4.6 EC-2.7.4.6]
+
** [http://enzyme.expasy.org/EC/1.21.99.4 EC-1.21.99.4]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[ATP]][c] '''+''' 1 [[UDP]][c] '''=>''' 1 [[UTP]][c] '''+''' 1 [[ADP]][c]
+
** 1 [[L-THYROXINE]][c] '''+''' 1 [[Donor-H2]][c] '''=>''' 1 [[CPD-387]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[Acceptor]][c] '''+''' 1 [[LIOTHYRONINE]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 ATP[c] '''+''' 1 UDP[c] '''=>''' 1 UTP[c] '''+''' 1 ADP[c]
+
** 1 L-thyroxine[c] '''+''' 1 a reduced electron acceptor[c] '''=>''' 1 iodide[c] '''+''' 1 H+[c] '''+''' 1 an oxidized electron acceptor[c] '''+''' 1 3,5,3'-triiodo-L-thyronine[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Tiso_gene_9290]]
+
* Gene: [[Tiso_gene_20481]]
−
** IN-SILICO_ANNOTATION
+
** Source: [[annotation-in-silico_annotation]]
−
***EC-NUMBER
+
*** Assignment: EC-NUMBER
−
* [[Tiso_gene_17272]]
+
−
** IN-SILICO_ANNOTATION
+
−
***EC-NUMBER
+
−
* [[Tiso_gene_195]]
+
−
** IN-SILICO_ANNOTATION
+
−
***EC-NUMBER
+
−
* [[Tiso_gene_17271]]
+
−
** IN-SILICO_ANNOTATION
+
−
***EC-NUMBER
+
−
* [[Tiso_gene_16529]]
+
−
** IN-SILICO_ANNOTATION
+
−
***EC-NUMBER
+
−
** EXPERIMENTAL_ANNOTATION
+
−
***EC-NUMBER
+
−
** [[pantograph]]-[[athaliana]]
+
−
** [[pantograph]]-[[synechocystis]]
+
−
** [[pantograph]]-[[esiliculosus]]
+
−
* [[Tiso_gene_18224]]
+
−
** IN-SILICO_ANNOTATION
+
−
***EC-NUMBER
+
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-7176]], UTP and CTP de novo biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7176 PWY-7176]
+
* [[PWY-6261]], thyroid hormone metabolism II (via conjugation and/or degradation): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6261 PWY-6261]
−
** '''3''' reactions found over '''3''' reactions in the full pathway
+
** '''11''' reactions found over '''15''' reactions in the full pathway
 +
* [[PWY-6260]], thyroid hormone metabolism I (via deiodination): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6260 PWY-6260]
 +
** '''3''' reactions found over '''12''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[orthology]]:
+
* Category: [[annotation]]
−
** [[pantograph]]:
+
** Source: [[annotation-in-silico_annotation]]
−
*** [[synechocystis]]
+
*** Tool: [[pathwaytools]]
−
*** [[athaliana]]
+
−
*** [[esiliculosus]]
+
−
* [[manual]]:
+
−
** [[primary_network]]
+
−
* [[annotation]]:
+
−
** [[pathwaytools]]:
+
−
*** [[experimental_annotation]]
+
−
*** [[in-silico_annotation]]
+
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=25098 25098]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19745 19745]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R00156 R00156]
+
** [http://www.genome.jp/dbget-bin/www_bget?R03734 R03734]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P21195 P21195]
 +
** [http://www.uniprot.org/uniprot/P49897 P49897]
 +
** [http://www.uniprot.org/uniprot/P49898 P49898]
 +
** [http://www.uniprot.org/uniprot/P05307 P05307]
 +
** [http://www.uniprot.org/uniprot/P09102 P09102]
 +
** [http://www.uniprot.org/uniprot/P07237 P07237]
 +
** [http://www.uniprot.org/uniprot/Q922C8 Q922C8]
 +
** [http://www.uniprot.org/uniprot/P04785 P04785]
 +
** [http://www.uniprot.org/uniprot/P24389 P24389]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=ORF}}
+
{{#set: common name=type_i_iodothyronine_deiodinase}}
−
{{#set: common name=nucleoside_diphosphate_kinase}}
+
{{#set: ec number=EC-1.21.99.4}}
−
{{#set: common name=adenylate_kinase_domain-containing_protein_1}}
+
{{#set: gene associated=Tiso_gene_20481}}
−
{{#set: ec number=EC-2.7.4.6}}
+
{{#set: in pathway=PWY-6261|PWY-6260}}
−
{{#set: gene associated=Tiso_gene_9290|Tiso_gene_17272|Tiso_gene_195|Tiso_gene_17271|Tiso_gene_16529|Tiso_gene_18224}}
+
−
{{#set: in pathway=PWY-7176}}
+
−
{{#set: reconstruction category=orthology}}
+
−
{{#set: reconstruction tool=pantograph}}
+
−
{{#set: reconstruction source=synechocystis|athaliana|esiliculosus}}
+
−
{{#set: reconstruction category=manual}}
+
−
{{#set: reconstruction source=primary_network}}
+
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction source=annotation-in-silico_annotation}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}
−
{{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
 

Latest revision as of 21:25, 21 March 2018

Reaction THYROXINE-DEIODINASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • type_i_iodothyronine_deiodinase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 L-thyroxine[c] + 1 a reduced electron acceptor[c] => 1 iodide[c] + 1 H+[c] + 1 an oxidized electron acceptor[c] + 1 3,5,3'-triiodo-L-thyronine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6261, thyroid hormone metabolism II (via conjugation and/or degradation): PWY-6261
    • 11 reactions found over 15 reactions in the full pathway
  • PWY-6260, thyroid hormone metabolism I (via deiodination): PWY-6260
    • 3 reactions found over 12 reactions in the full pathway

Reconstruction information

External links





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