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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=5.99.1.2-RXN 5.99.1.2-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD0-341 CPD0-341] == |
− | * direction: | + | * smiles: |
− | ** REVERSIBLE | + | ** C(N)(=O)CCCCC(SC(=O)CCC(=O)[O-])CCS |
| * common name: | | * common name: |
− | ** dna_topoisomerase | + | ** S-succinyl-dihydrolipoamide |
− | ** dna_topoisomerase1 | + | * inchi key: |
− | * ec number: | + | ** InChIKey=RJCJWONCSKSHES-VIFPVBQESA-M |
− | ** [http://enzyme.expasy.org/EC/5.99.1.2 EC-5.99.1.2] | + | * molecular weight: |
| + | ** 306.414 |
| * Synonym(s): | | * Synonym(s): |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
− | ** 1 [[Negatively-super-coiled-DNAs]][c] '''<=>''' 1 [[Relaxed-DNAs]][c]
| + | == Reaction(s) of unknown directionality == |
− | * With common name(s):
| + | * [[AKGDHe2r]] |
− | ** 1 a negatively supercoiled DNA[c] '''<=>''' 1 a relaxed DNA[c]
| + | |
− | | + | |
− | == Genes associated with this reaction ==
| + | |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * [[Tiso_gene_5747]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_1740]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_6569]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | ** EXPERIMENTAL_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_3425]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_5036]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_1291]]
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_5035]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_5748]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_14333]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_200]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[Tiso_gene_10513]]
| + | |
− | ** EXPERIMENTAL_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_1739]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | * [[Tiso_gene_5749]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | == Pathways == | + | |
− | == Reconstruction information == | + | |
− | * [[orthology]]: | + | |
− | ** [[pantograph]]:
| + | |
− | *** [[esiliculosus]]
| + | |
− | * [[annotation]]:
| + | |
− | ** [[pathwaytools]]:
| + | |
− | *** [[experimental_annotation]]
| + | |
− | *** [[in-silico_annotation]]
| + | |
| == External links == | | == External links == |
− | * UNIPROT: | + | * PUBCHEM: |
− | ** [http://www.uniprot.org/uniprot/Q7M0H8 Q7M0H8] | + | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=90657579 90657579] |
− | ** [http://www.uniprot.org/uniprot/Q07050 Q07050]
| + | * HMDB : HMDB01177 |
− | ** [http://www.uniprot.org/uniprot/Q9JWZ5 Q9JWZ5]
| + | * CHEBI: |
− | ** [http://www.uniprot.org/uniprot/Q59046 Q59046] | + | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=17432 17432] |
− | ** [http://www.uniprot.org/uniprot/Q9PLZ2 Q9PLZ2] | + | * LIGAND-CPD: |
− | ** [http://www.uniprot.org/uniprot/P47368 P47368] | + | ** [http://www.genome.jp/dbget-bin/www_bget?C01169 C01169] |
− | ** [http://www.uniprot.org/uniprot/Q9CG80 Q9CG80]
| + | {{#set: smiles=C(N)(=O)CCCCC(SC(=O)CCC(=O)[O-])CCS}} |
− | ** [http://www.uniprot.org/uniprot/P43704 P43704]
| + | {{#set: common name=S-succinyl-dihydrolipoamide}} |
− | ** [http://www.uniprot.org/uniprot/P43012 P43012] | + | {{#set: inchi key=InChIKey=RJCJWONCSKSHES-VIFPVBQESA-M}} |
− | ** [http://www.uniprot.org/uniprot/P0A620 P0A620] | + | {{#set: molecular weight=306.414 }} |
− | ** [http://www.uniprot.org/uniprot/P04786 P04786]
| + | {{#set: reversible reaction associated=AKGDHe2r}} |
− | ** [http://www.uniprot.org/uniprot/P13099 P13099]
| + | |
− | ** [http://www.uniprot.org/uniprot/P06612 P06612]
| + | |
− | ** [http://www.uniprot.org/uniprot/P11387 P11387]
| + | |
− | ** [http://www.uniprot.org/uniprot/P07799 P07799]
| + | |
− | ** [http://www.uniprot.org/uniprot/P93119 P93119]
| + | |
− | ** [http://www.uniprot.org/uniprot/O13463 O13463]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q94705 Q94705]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q04750 Q04750]
| + | |
− | ** [http://www.uniprot.org/uniprot/P14294 P14294]
| + | |
− | ** [http://www.uniprot.org/uniprot/P30181 P30181]
| + | |
− | ** [http://www.uniprot.org/uniprot/P34185 P34185]
| + | |
− | ** [http://www.uniprot.org/uniprot/P30189 P30189]
| + | |
− | ** [http://www.uniprot.org/uniprot/P40114 P40114]
| + | |
− | ** [http://www.uniprot.org/uniprot/P41511 P41511]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q8I3Z9 Q8I3Z9]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q26024 Q26024]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q27529 Q27529]
| + | |
− | ** [http://www.uniprot.org/uniprot/P41512 P41512]
| + | |
− | ** [http://www.uniprot.org/uniprot/O24307 O24307]
| + | |
− | ** [http://www.uniprot.org/uniprot/P71196 P71196]
| + | |
− | ** [http://www.uniprot.org/uniprot/O70157 O70157]
| + | |
− | ** [http://www.uniprot.org/uniprot/O60126 O60126]
| + | |
− | ** [http://www.uniprot.org/uniprot/O61660 O61660]
| + | |
− | {{#set: direction=REVERSIBLE}} | + | |
− | {{#set: common name=dna_topoisomerase}}
| + | |
− | {{#set: common name=dna_topoisomerase1}} | + | |
− | {{#set: ec number=EC-5.99.1.2}}
| + | |
− | {{#set: gene associated=Tiso_gene_5747|Tiso_gene_1740|Tiso_gene_6569|Tiso_gene_3425|Tiso_gene_5036|Tiso_gene_1291|Tiso_gene_5035|Tiso_gene_5748|Tiso_gene_14333|Tiso_gene_200|Tiso_gene_10513|Tiso_gene_1739|Tiso_gene_5749}} | + | |
− | {{#set: in pathway=}}
| + | |
− | {{#set: reconstruction category=orthology}} | + | |
− | {{#set: reconstruction tool=pantograph}} | + | |
− | {{#set: reconstruction source=esiliculosus}}
| + | |
− | {{#set: reconstruction category=annotation}}
| + | |
− | {{#set: reconstruction tool=pathwaytools}}
| + | |
− | {{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
| + | |