Difference between revisions of "MALATE-DEH-RXN"

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(Created page with "Category:Gene == Gene Tiso_gene_2105 == * left end position: ** 18554 * transcription direction: ** POSITIVE * right end position: ** 20045 * centisome position: ** 61.372...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=MALATE-DEH-RXN MALATE-DEH-RXN] == * direction: ** REVERSIBLE * common name: ** malate_dehydrogenase...")
 
(2 intermediate revisions by the same user not shown)
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−
[[Category:Gene]]
+
[[Category:Reaction]]
−
== Gene Tiso_gene_2105 ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=MALATE-DEH-RXN MALATE-DEH-RXN] ==
−
* left end position:
+
* direction:
−
** 18554
+
** REVERSIBLE
−
* transcription direction:
+
* common name:
−
** POSITIVE
+
** malate_dehydrogenase_mitochondrial
−
* right end position:
+
* ec number:
−
** 20045
+
** [http://enzyme.expasy.org/EC/1.1.1.37 EC-1.1.1.37]
−
* centisome position:
+
−
** 61.372055   
+
 
* Synonym(s):
 
* Synonym(s):
 +
** malate dehydrogenation
  
−
== Reactions associated ==
+
== Reaction Formula ==
−
* [[MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN]]
+
* With identifiers:
−
** in-silico_annotation
+
** 1 [[MAL]][c] '''+''' 1 [[NAD]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[OXALACETIC_ACID]][c] '''+''' 1 [[NADH]][c]
−
***automated-name-match
+
* With common name(s):
−
== Pathways associated ==
+
** 1 (S)-malate[c] '''+''' 1 NAD+[c] '''<=>''' 1 H+[c] '''+''' 1 oxaloacetate[c] '''+''' 1 NADH[c]
−
* [[PWY-7375]]
+
 
 +
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[Tiso_gene_2323]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-synechocystis]]
 +
** Source: [[orthology-esiliculosus]]
 +
** Source: [[orthology-creinhardtii]]
 +
* Gene: [[Tiso_gene_1990]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-esiliculosus]]
 +
** Source: [[orthology-creinhardtii]]
 +
== Pathways ==
 +
* [[PWY-561]], superpathway of glyoxylate cycle and fatty acid degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-561 PWY-561]
 +
** '''5''' reactions found over '''8''' reactions in the full pathway
 +
* [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-1622]], formaldehyde assimilation I (serine pathway): [http://metacyc.org/META/NEW-IMAGE?object=PWY-1622 PWY-1622]
 +
** '''5''' reactions found over '''13''' reactions in the full pathway
 +
* [[PWY66-399]], gluconeogenesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-399 PWY66-399]
 +
** '''10''' reactions found over '''12''' reactions in the full pathway
 +
* [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
 +
** '''4''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-7383]], anaerobic energy metabolism (invertebrates, cytosol): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7383 PWY-7383]
 +
** '''5''' reactions found over '''7''' reactions in the full pathway
 +
* [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
 +
** '''5''' reactions found over '''12''' reactions in the full pathway
 +
* [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
 +
** '''7''' reactions found over '''10''' reactions in the full pathway
 +
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
 +
** '''9''' reactions found over '''11''' reactions in the full pathway
 +
* [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
 +
** '''7''' reactions found over '''12''' reactions in the full pathway
 +
* [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
 +
** '''6''' reactions found over '''9''' reactions in the full pathway
 +
* [[GLYOXYLATE-BYPASS]], glyoxylate cycle: [http://metacyc.org/META/NEW-IMAGE?object=GLYOXYLATE-BYPASS GLYOXYLATE-BYPASS]
 +
** '''6''' reactions found over '''6''' reactions in the full pathway
 +
* [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
 +
** '''9''' reactions found over '''16''' reactions in the full pathway
 +
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
 +
** '''11''' reactions found over '''18''' reactions in the full pathway
 +
* [[PWY-7115]], C4 photosynthetic carbon assimilation cycle, NAD-ME type: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7115 PWY-7115]
 +
** '''7''' reactions found over '''9''' reactions in the full pathway
 +
* [[GLUCONEO-PWY]], gluconeogenesis I: [http://metacyc.org/META/NEW-IMAGE?object=GLUCONEO-PWY GLUCONEO-PWY]
 +
** '''13''' reactions found over '''13''' reactions in the full pathway
 +
* [[P108-PWY]], pyruvate fermentation to propanoate I: [http://metacyc.org/META/NEW-IMAGE?object=P108-PWY P108-PWY]
 +
** '''3''' reactions found over '''7''' reactions in the full pathway
 +
* [[MALATE-ASPARTATE-SHUTTLE-PWY]], L-aspartate degradation II: [http://metacyc.org/META/NEW-IMAGE?object=MALATE-ASPARTATE-SHUTTLE-PWY MALATE-ASPARTATE-SHUTTLE-PWY]
 +
** '''2''' reactions found over '''2''' reactions in the full pathway
 +
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
 +
** '''10''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
 +
** '''9''' reactions found over '''12''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-athaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-creinhardtii]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-synechocystis]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[manual]]
 +
** Source: [[manual-primary_network]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
{{#set: left end position=18554}}
+
* RHEA:
−
{{#set: transcription direction=POSITIVE}}
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21432 21432]
−
{{#set: right end position=20045}}
+
* PIR:
−
{{#set: centisome position=61.372055    }}
+
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A32472 A32472]
−
{{#set: reaction associated=MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN}}
+
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A49496 A49496]
−
{{#set: pathway associated=PWY-7375}}
+
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A60689 A60689]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=C64110 C64110]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=D81399 D81399]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEBYMC DEBYMC]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEBYMM DEBYMM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEBYMP DEBYMP]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEEBM DEEBM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEECM DEECM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEMSMC DEMSMC]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEMSMM DEMSMM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEPGMM DEPGMM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEPUGW DEPUGW]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DEPUMW DEPUMW]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DERTMM DERTMM]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=DETWMA DETWMA]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=F85551 F85551]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=G01650 G01650]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H64477 H64477]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=I40383 I40383]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PA0040 PA0040]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PA0079 PA0079]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PN0162 PN0162]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S03352 S03352]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S03958 S03958]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S04956 S04956]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S04957 S04957]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S04958 S04958]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S04959 S04959]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S04960 S04960]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S04961 S04961]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S07574 S07574]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S08981 S08981]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S44167 S44167]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S52039 S52039]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S57958 S57958]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S61213 S61213]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S75735 S75735]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T03272 T03272]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T06325 T06325]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T06326 T06326]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T06327 T06327]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T06328 T06328]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T06386 T06386]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T08015 T08015]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T08077 T08077]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T08177 T08177]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09228 T09228]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09263 T09263]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09286 T09286]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09291 T09291]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T09294 T09294]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T12433 T12433]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T18570 T18570]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T45206 T45206]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T45208 T45208]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T49932 T49932]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T51311 T51311]
 +
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T51862 T51862]
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R00342 R00342]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/Q07841 Q07841]
 +
** [http://www.uniprot.org/uniprot/P33163 P33163]
 +
** [http://www.uniprot.org/uniprot/P44427 P44427]
 +
** [http://www.uniprot.org/uniprot/Q9PHY2 Q9PHY2]
 +
** [http://www.uniprot.org/uniprot/P22133 P22133]
 +
** [http://www.uniprot.org/uniprot/P17505 P17505]
 +
** [http://www.uniprot.org/uniprot/P32419 P32419]
 +
** [http://www.uniprot.org/uniprot/P25077 P25077]
 +
** [http://www.uniprot.org/uniprot/P14152 P14152]
 +
** [http://www.uniprot.org/uniprot/Q8R1P0 Q8R1P0]
 +
** [http://www.uniprot.org/uniprot/P19446 P19446]
 +
** [http://www.uniprot.org/uniprot/P17783 P17783]
 +
** [http://www.uniprot.org/uniprot/P04636 P04636]
 +
** [http://www.uniprot.org/uniprot/P58408 P58408]
 +
** [http://www.uniprot.org/uniprot/Q58820 Q58820]
 +
** [http://www.uniprot.org/uniprot/P49814 P49814]
 +
** [http://www.uniprot.org/uniprot/Q93ZA7 Q93ZA7]
 +
** [http://www.uniprot.org/uniprot/Q7M4Y9 Q7M4Y9]
 +
** [http://www.uniprot.org/uniprot/Q7M4Z0 Q7M4Z0]
 +
** [http://www.uniprot.org/uniprot/P10887 P10887]
 +
** [http://www.uniprot.org/uniprot/P11386 P11386]
 +
** [http://www.uniprot.org/uniprot/P19983 P19983]
 +
** [http://www.uniprot.org/uniprot/P19981 P19981]
 +
** [http://www.uniprot.org/uniprot/P19979 P19979]
 +
** [http://www.uniprot.org/uniprot/P19977 P19977]
 +
** [http://www.uniprot.org/uniprot/P19982 P19982]
 +
** [http://www.uniprot.org/uniprot/P19978 P19978]
 +
** [http://www.uniprot.org/uniprot/P19980 P19980]
 +
** [http://www.uniprot.org/uniprot/P16142 P16142]
 +
** [http://www.uniprot.org/uniprot/P46487 P46487]
 +
** [http://www.uniprot.org/uniprot/P46488 P46488]
 +
** [http://www.uniprot.org/uniprot/Q43744 Q43744]
 +
** [http://www.uniprot.org/uniprot/Q59202 Q59202]
 +
** [http://www.uniprot.org/uniprot/Q55383 Q55383]
 +
** [http://www.uniprot.org/uniprot/Q42972 Q42972]
 +
** [http://www.uniprot.org/uniprot/O81278 O81278]
 +
** [http://www.uniprot.org/uniprot/O81279 O81279]
 +
** [http://www.uniprot.org/uniprot/O65363 O65363]
 +
** [http://www.uniprot.org/uniprot/O65364 O65364]
 +
** [http://www.uniprot.org/uniprot/O81609 O81609]
 +
** [http://www.uniprot.org/uniprot/Q43743 Q43743]
 +
** [http://www.uniprot.org/uniprot/Q42686 Q42686]
 +
** [http://www.uniprot.org/uniprot/P93106 P93106]
 +
** [http://www.uniprot.org/uniprot/Q04820 Q04820]
 +
** [http://www.uniprot.org/uniprot/O48903 O48903]
 +
** [http://www.uniprot.org/uniprot/O48904 O48904]
 +
** [http://www.uniprot.org/uniprot/O48905 O48905]
 +
** [http://www.uniprot.org/uniprot/O48906 O48906]
 +
** [http://www.uniprot.org/uniprot/O24047 O24047]
 +
** [http://www.uniprot.org/uniprot/Q9XTB4 Q9XTB4]
 +
** [http://www.uniprot.org/uniprot/P50917 P50917]
 +
** [http://www.uniprot.org/uniprot/Q49981 Q49981]
 +
** [http://www.uniprot.org/uniprot/Q9ZP05 Q9ZP05]
 +
** [http://www.uniprot.org/uniprot/Q9ZP06 Q9ZP06]
 +
** [http://www.uniprot.org/uniprot/Q9SN86 Q9SN86]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=malate_dehydrogenase_mitochondrial}}
 +
{{#set: ec number=EC-1.1.1.37}}
 +
{{#set: common name=malate dehydrogenation}}
 +
{{#set: gene associated=Tiso_gene_2323|Tiso_gene_1990}}
 +
{{#set: in pathway=PWY-561|PWY-5913|PWY-1622|PWY66-399|P42-PWY|PWY-7383|PWY-5392|TCA|P105-PWY|P23-PWY|PWY-5690|GLYOXYLATE-BYPASS|FERMENTATION-PWY|PWY-6728|PWY-7115|GLUCONEO-PWY|P108-PWY|MALATE-ASPARTATE-SHUTTLE-PWY|PWY66-398|PWY-6969}}
 +
{{#set: reconstruction category=orthology|manual|annotation}}
 +
{{#set: reconstruction source=annotation-experimental_annotation|orthology-esiliculosus|annotation-in-silico_annotation|orthology-athaliana|orthology-synechocystis|manual-primary_network|orthology-creinhardtii}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:08, 21 March 2018

Reaction MALATE-DEH-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • malate_dehydrogenase_mitochondrial
  • ec number:
  • Synonym(s):
    • malate dehydrogenation

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 (S)-malate[c] + 1 NAD+[c] <=> 1 H+[c] + 1 oxaloacetate[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-561, superpathway of glyoxylate cycle and fatty acid degradation: PWY-561
    • 5 reactions found over 8 reactions in the full pathway
  • PWY-5913, partial TCA cycle (obligate autotrophs): PWY-5913
    • 9 reactions found over 11 reactions in the full pathway
  • PWY-1622, formaldehyde assimilation I (serine pathway): PWY-1622
    • 5 reactions found over 13 reactions in the full pathway
  • PWY66-399, gluconeogenesis III: PWY66-399
    • 10 reactions found over 12 reactions in the full pathway
  • P42-PWY, incomplete reductive TCA cycle: P42-PWY
    • 4 reactions found over 7 reactions in the full pathway
  • PWY-7383, anaerobic energy metabolism (invertebrates, cytosol): PWY-7383
    • 5 reactions found over 7 reactions in the full pathway
  • PWY-5392, reductive TCA cycle II: PWY-5392
    • 5 reactions found over 12 reactions in the full pathway
  • TCA, TCA cycle I (prokaryotic): TCA
    • 7 reactions found over 10 reactions in the full pathway
  • P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
    • 9 reactions found over 11 reactions in the full pathway
  • P23-PWY, reductive TCA cycle I: P23-PWY
    • 7 reactions found over 12 reactions in the full pathway
  • PWY-5690, TCA cycle II (plants and fungi): PWY-5690
    • 6 reactions found over 9 reactions in the full pathway
  • GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
    • 6 reactions found over 6 reactions in the full pathway
  • FERMENTATION-PWY, mixed acid fermentation: FERMENTATION-PWY
    • 9 reactions found over 16 reactions in the full pathway
  • PWY-6728, methylaspartate cycle: PWY-6728
    • 11 reactions found over 18 reactions in the full pathway
  • PWY-7115, C4 photosynthetic carbon assimilation cycle, NAD-ME type: PWY-7115
    • 7 reactions found over 9 reactions in the full pathway
  • GLUCONEO-PWY, gluconeogenesis I: GLUCONEO-PWY
    • 13 reactions found over 13 reactions in the full pathway
  • P108-PWY, pyruvate fermentation to propanoate I: P108-PWY
    • 3 reactions found over 7 reactions in the full pathway
  • MALATE-ASPARTATE-SHUTTLE-PWY, L-aspartate degradation II: MALATE-ASPARTATE-SHUTTLE-PWY
    • 2 reactions found over 2 reactions in the full pathway
  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 10 reactions found over 11 reactions in the full pathway
  • PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
    • 9 reactions found over 12 reactions in the full pathway

Reconstruction information

External links





Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=MALATE-DEH-RXN&oldid=46279"