Difference between revisions of "AICARTRANSFORM-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-8120 CPD-8120] == * smiles: ** CCCCCC=CCC=CCC=CCCCCCCC(=O)[O-] * inchi key: ** InChIKey=HOB...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=AICARTRANSFORM-RXN AICARTRANSFORM-RXN] == * direction: ** REVERSIBLE * common name: ** bifunctional...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-8120 CPD-8120] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=AICARTRANSFORM-RXN AICARTRANSFORM-RXN] ==
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* smiles:
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* direction:
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** CCCCCC=CCC=CCC=CCCCCCCC(=O)[O-]
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** REVERSIBLE
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* inchi key:
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** InChIKey=HOBAELRKJCKHQD-QNEBEIHSSA-M
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* common name:
 
* common name:
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** di-homo-γ-linolenate
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** bifunctional_purine_biosynthesis
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* molecular weight:
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* ec number:
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** 305.479   
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** [http://enzyme.expasy.org/EC/2.1.2.3 EC-2.1.2.3]
 
* Synonym(s):
 
* Synonym(s):
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** (8Z,11Z,14Z)-eicosatrienoic acid
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** 5-aminoimidazole-4-carboxamide ribonucleotide transformylase
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** DGLA
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** (8Z,11Z,14Z)-eicosatri-8,11,14-enoate
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** (8Z,11Z,14Z)-icosatrienoate
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** di-homo-γ-linolenic acid
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** (Z,Z,Z)-8,11,14-eicosatrienoic acid
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** (Z,Z,Z)-8,11,14-eicosatrienoate
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** (8Z,11Z,14Z)-eicosatrienoate
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** (8Z,11Z,14Z)-icosatrienoic acid
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** (8Z,11Z,14Z)-icosa-8,11,14-trienoate
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[RXN-13435]]
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** 1 [[FORMYL-THF-GLU-N]][c] '''+''' 1 [[AICAR]][c] '''<=>''' 1 [[PHOSPHORIBOSYL-FORMAMIDO-CARBOXAMIDE]][c] '''+''' 1 [[THF-GLU-N]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 an N10-formyl-tetrahydrofolate[c] '''+''' 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide[c] '''<=>''' 1 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide[c] '''+''' 1 a tetrahydrofolate[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_18420]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-esiliculosus]]
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== Pathways  ==
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* [[PWY-6123]], inosine-5'-phosphate biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6123 PWY-6123]
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** '''5''' reactions found over '''6''' reactions in the full pathway
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* [[PWY-6124]], inosine-5'-phosphate biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6124 PWY-6124]
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** '''5''' reactions found over '''5''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-esiliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[manual]]
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** Source: [[manual-primary_network]]
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
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** Source: [[annotation-experimental_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* Wikipedia : Dihomo-gamma-linolenic_acid
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* RHEA:
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* PUBCHEM:
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22192 22192]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=21158448 21158448]
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* LIGAND-RXN:
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* HMDB : HMDB02925
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** [http://www.genome.jp/dbget-bin/www_bget?R04560 R04560]
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* LIGAND-CPD:
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* UNIPROT:
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** [http://www.genome.jp/dbget-bin/www_bget?C03242 C03242]
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** [http://www.uniprot.org/uniprot/P43852 P43852]
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* CHEMSPIDER:
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** [http://www.uniprot.org/uniprot/P12048 P12048]
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** [http://www.chemspider.com/Chemical-Structure.20117973.html 20117973]
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** [http://www.uniprot.org/uniprot/P31335 P31335]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/P26978 P26978]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=71589 71589]
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** [http://www.uniprot.org/uniprot/P15639 P15639]
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{{#set: smiles=CCCCCC=CCC=CCC=CCCCCCCC(=O)[O-]}}
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** [http://www.uniprot.org/uniprot/Q9PNY2 Q9PNY2]
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{{#set: inchi key=InChIKey=HOBAELRKJCKHQD-QNEBEIHSSA-M}}
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** [http://www.uniprot.org/uniprot/Q9JUQ8 Q9JUQ8]
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{{#set: common name=di-homo-&gamma;-linolenate}}
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** [http://www.uniprot.org/uniprot/P31939 P31939]
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{{#set: molecular weight=305.479    }}
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** [http://www.uniprot.org/uniprot/Q59493 Q59493]
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{{#set: common name=(8Z,11Z,14Z)-eicosatrienoic acid|DGLA|(8Z,11Z,14Z)-eicosatri-8,11,14-enoate|(8Z,11Z,14Z)-icosatrienoate|di-homo-&gamma;-linolenic acid|(Z,Z,Z)-8,11,14-eicosatrienoic acid|(Z,Z,Z)-8,11,14-eicosatrienoate|(8Z,11Z,14Z)-eicosatrienoate|(8Z,11Z,14Z)-icosatrienoic acid|(8Z,11Z,14Z)-icosa-8,11,14-trienoate}}
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** [http://www.uniprot.org/uniprot/P38009 P38009]
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{{#set: produced by=RXN-13435}}
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** [http://www.uniprot.org/uniprot/P54113 P54113]
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** [http://www.uniprot.org/uniprot/O64767 O64767]
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** [http://www.uniprot.org/uniprot/O74928 O74928]
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{{#set: direction=REVERSIBLE}}
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{{#set: common name=bifunctional_purine_biosynthesis}}
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{{#set: ec number=EC-2.1.2.3}}
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{{#set: common name=5-aminoimidazole-4-carboxamide ribonucleotide transformylase}}
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{{#set: gene associated=Tiso_gene_18420}}
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{{#set: in pathway=PWY-6123|PWY-6124}}
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{{#set: reconstruction category=orthology|manual|annotation}}
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{{#set: reconstruction source=annotation-in-silico_annotation|manual-primary_network|annotation-experimental_annotation|orthology-esiliculosus}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:21, 21 March 2018

Reaction AICARTRANSFORM-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • bifunctional_purine_biosynthesis
  • ec number:
  • Synonym(s):
    • 5-aminoimidazole-4-carboxamide ribonucleotide transformylase

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 an N10-formyl-tetrahydrofolate[c] + 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide[c] <=> 1 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide[c] + 1 a tetrahydrofolate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6123, inosine-5'-phosphate biosynthesis I: PWY-6123
    • 5 reactions found over 6 reactions in the full pathway
  • PWY-6124, inosine-5'-phosphate biosynthesis II: PWY-6124
    • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

External links





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