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− | [[Category:Metabolite]] | + | [[Category:Gene]] |
− | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NAD NAD] == | + | == Gene Tiso_gene_13061 == |
− | * smiles: | + | * right end position: |
− | ** C1(C(=CC=C[N+]=1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O) | + | ** 4959 |
− | * inchi key: | + | * transcription direction: |
− | ** InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-M | + | ** POSITIVE |
− | * common name: | + | * left end position: |
− | ** NAD+ | + | ** 2962 |
− | * molecular weight: | + | * centisome position: |
− | ** 662.422 | + | ** 45.193775 |
| * Synonym(s): | | * Synonym(s): |
− | ** NAD+
| |
− | ** beta-nicotinamide adenine dinucleotide
| |
− | ** coenzyme I
| |
− | ** diphosphopyridine nucleotide
| |
− | ** diphosphopyridine nucleotide oxidized
| |
− | ** nicotinamide adenine dinucleotide
| |
− | ** nicotinamide adenine dinucleotide oxidized
| |
− | ** NAD-oxidized
| |
− | ** NAD-ox
| |
− | ** DPN+
| |
− | ** DPN-ox
| |
− | ** DPN
| |
− | ** β-nicotinamide adenine dinucleotide
| |
− | ** NAD
| |
− | ** β-NAD+
| |
| | | |
− | == Reaction(s) known to consume the compound == | + | == Reactions associated == |
− | * [[RXN-905]] | + | * Reaction: [[PROLINE-RACEMASE-RXN]] |
− | * [[RXN-12490]]
| + | ** Source: [[annotation-in-silico_annotation]] |
− | * [[RXN66-476-CPD-388/NAD/WATER//CPD-8462/NADH/PROTON.40.]]
| + | *** Assignment: ec-number |
− | * [[RXN66-476-CPD-14719/NAD/WATER//CPD-7830/NADH/PROTON.42.]]
| + | == Pathways associated == |
− | * [[1.1.1.39-RXN]]
| + | * [[PWY-6344]] |
− | * [[PREPHENATEDEHYDROG-RXN]]
| + | |
− | * [[ALDDH]]
| + | |
− | * [[RXN-11213]]
| + | |
− | * [[1.5.1.7-RXN]]
| + | |
− | * [[RXN-13158]]
| + | |
− | * [[2.7.1.160-RXN]]
| + | |
− | * [[RXN-12789]]
| + | |
− | * [[3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN]]
| + | |
− | * [[PYRIDOXAL-4-DEHYDROGENASE-RXN]]
| + | |
− | * [[R222-RXN]]
| + | |
− | * [[RXN-13414]]
| + | |
− | * [[RXN-12705]]
| + | |
− | * [[RXN-8001]]
| + | |
− | * [[RXN-14249]]
| + | |
− | * [[RXN-17115]]
| + | |
− | * [[RXN66-3]]
| + | |
− | * [[ALDH_im4ac]]
| + | |
− | * [[AMINOBUTDEHYDROG-RXN]]
| + | |
− | * [[RXN-14393]]
| + | |
− | * [[RXN-1884]]
| + | |
− | * [[HISTALDEHYD-RXN]]
| + | |
− | * [[RXN66-353]]
| + | |
− | * [[DHBDEHYD-RXN]]
| + | |
− | * [[RXNQT-4178]]
| + | |
− | * [[1.2.1.25-RXN]]
| + | |
− | * [[RXN-10089]]
| + | |
− | * [[ALDHDEHYDROG-RXN]]
| + | |
− | * [[2-KETO-ADIPATE-DEHYDROG-RXN]]
| + | |
− | * [[RXN-8162]]
| + | |
− | * [[RXN-12693]]
| + | |
− | * [[IMDH]]
| + | |
− | * [[PYRUVDEH-RXN]]
| + | |
− | * [[RXN-11245]]
| + | |
− | * [[RXN-10715]]
| + | |
− | * [[RXNQT-4174]]
| + | |
− | * [[THREODEHYD-RXN]]
| + | |
− | * [[HBCO]]
| + | |
− | * [[RXNQT-4171]]
| + | |
− | * [[RXN-2902]]
| + | |
− | * [[1.2.1.65-RXN]]
| + | |
− | * [[RXN-12750]]
| + | |
− | * [[2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN]]
| + | |
− | * [[GLYCOLALD-DEHYDROG-RXN]]
| + | |
− | * [[RXN-37]]
| + | |
− | * [[RXN66-479]]
| + | |
− | * [[OHACYL-COA-DEHYDROG-RXN]]
| + | |
− | * [[NAD-KIN-RXN]]
| + | |
− | * [[RXN66-472]]
| + | |
− | * [[RXN66-476]]
| + | |
− | * [[RXN-16559]]
| + | |
− | * [[UDPGALor]]
| + | |
− | * [[RXN-17786]]
| + | |
− | * [[RXN-17781]]
| + | |
− | * [[1.5.1.9-RXN]]
| + | |
− | * [[RXNQT-4168]]
| + | |
− | * [[RXN-10702]]
| + | |
− | * [[RXN-10703]]
| + | |
− | * [[RXNQT-4165]]
| + | |
− | * [[1.2.1.27-RXN]]
| + | |
− | * [[RXN0-1132]]
| + | |
− | * [[R00476]]
| + | |
− | * [[RXN-10780]]
| + | |
− | * [[RXN-17777]]
| + | |
− | * [[RXN-14116]]
| + | |
− | * [[RXN-12581]]
| + | |
− | * [[RXN-7682]]
| + | |
− | * [[RXN-17794]]
| + | |
− | * [[RXN66-478]]
| + | |
− | * [[RXN-17790]]
| + | |
− | * [[PYRROLINECARBDEHYDROG-RXN]]
| + | |
− | * [[1.8.1.4-RXN]]
| + | |
− | * [[RXN-17798]]
| + | |
− | * [[QUINATE-5-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN66-342]]
| + | |
− | * [[BNorh]]
| + | |
− | * [[RXN-12507]]
| + | |
− | * [[ALDDHm]]
| + | |
− | * [[RXN-14271]]
| + | |
− | * [[DIMETHUROPORDEHYDROG-RXN]]
| + | |
− | * [[RXN-14275]]
| + | |
− | * [[SSNOm]]
| + | |
− | * [[RXN-7745]]
| + | |
− | * [[RXN-10698]]
| + | |
− | * [[RXN-16136]]
| + | |
− | * [[SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN-14986]]
| + | |
− | * [[BNor]]
| + | |
− | * [[RXN0-5248]]
| + | |
− | == Reaction(s) known to produce the compound ==
| + | |
− | * [[RXN1G-248]]
| + | |
− | * [[RXN-9660]]
| + | |
− | * [[RXN-11195]]
| + | |
− | * [[RXN1G-1057]] | + | |
− | * [[GLUTAMATE-SYNTHASE-NADH-RXN]] | + | |
− | * [[RXN1G-679]] | + | |
− | * [[GDRm]] | + | |
− | * [[RXN-10062]] | + | |
− | * [[RXN-5424]]
| + | |
− | * [[RXN-11478]]
| + | |
− | * [[RXN-8025]]
| + | |
− | * [[GDRh]]
| + | |
− | * [[1.5.1.20-RXN]]
| + | |
− | * [[RXN1G-509]]
| + | |
− | * [[RXN1G-337]]
| + | |
− | * [[RXN-3661]]
| + | |
− | * [[NODOx]]
| + | |
− | * [[RXN3O-4113]]
| + | |
− | * [[RXN1G-285]]
| + | |
− | * [[R07562]]
| + | |
− | * [[NADHor_2m]]
| + | |
− | * [[ACDHi]]
| + | |
− | * [[RXN1G-488]]
| + | |
− | * [[RXN1G-526]]
| + | |
− | * [[RXN-9659]]
| + | |
− | * [[RXN-9658]]
| + | |
− | * [[RXN-10911]]
| + | |
− | * [[RXN-11482]]
| + | |
− | * [[R4-RXN]]
| + | |
− | * [[RXN-9635]]
| + | |
− | * [[RXN1G-915]]
| + | |
− | * [[ENOYL-ACP-REDUCT-NADH-RXN]]
| + | |
− | * [[RXN1G-196]]
| + | |
− | * [[RXN1G-396]]
| + | |
− | * [[RXN1G-37]]
| + | |
− | * [[RXN-10657]]
| + | |
− | * [[RXN-7694]]
| + | |
− | * [[1.1.1.8-RXN]]
| + | |
− | * [[GLYCERATE-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN1G-339]]
| + | |
− | * [[RXN0-5330]]
| + | |
− | * [[RXN1G-471]]
| + | |
− | * [[RXN1G-210]]
| + | |
− | * [[GLYCLTD]]
| + | |
− | * [[ALCDHi]]
| + | |
− | * [[RXN-7700]]
| + | |
− | * [[ACDHmi]]
| + | |
− | * [[RXN-7706]]
| + | |
− | * [[ALCDHmi]]
| + | |
− | * [[RXN0-2145]]
| + | |
− | * [[RXN1G-395]]
| + | |
− | * [[RXN1G-299]]
| + | |
− | * [[MTHFO]]
| + | |
− | * [[CYTOCHROME-B5-REDUCTASE-RXN]]
| + | |
− | * [[RXN1G-276]]
| + | |
− | * [[RXN-12997]]
| + | |
− | * [[RXN1G-820]]
| + | |
− | * [[1.6.5.4-RXN]]
| + | |
− | * [[4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN1G-686]]
| + | |
− | * [[RXN-9662]]
| + | |
− | * [[RXN-9663]]
| + | |
− | * [[GDR]]
| + | |
− | * [[RXN-9661]]
| + | |
− | * [[RXN1G-1325]]
| + | |
− | * [[RXN1G-468]]
| + | |
− | * [[RXN-9558]]
| + | |
− | * [[RXN1G-607]]
| + | |
− | * [[RXN1G-171]]
| + | |
− | * [[RXN-12570]]
| + | |
− | * [[RXN-5822]]
| + | |
− | * [[RXN1G-962]]
| + | |
− | * [[RXN-9657]]
| + | |
− | * [[RXN1G-1130]]
| + | |
− | * [[RXN1G-1117]]
| + | |
− | * [[RXN-10661]]
| + | |
− | * [[NITRATE-REDUCTASE-NADH-RXN]]
| + | |
− | * [[RXN1G-193]]
| + | |
− | * [[RXN-8026]]
| + | |
− | * [[RXN-10781]]
| + | |
− | * [[RXN-13417]]
| + | |
− | == Reaction(s) of unknown directionality == | + | |
− | * [[1.1.1.255-RXN]] | + | |
− | * [[HMNOS]]
| + | |
− | * [[MANNPDEHYDROG-RXN]]
| + | |
− | * [[RXN-161]]
| + | |
− | * [[RXN-7719]]
| + | |
− | * [[ALLYSINE-DEHYDROG-RXN]]
| + | |
− | * [[PHENDEHYD-RXN]]
| + | |
− | * [[RXN-18206]]
| + | |
− | * [[D-THREO-ALDOSE-1-DEHYDROGENASE-RXN]]
| + | |
− | * [[NADH-DEHYDROG-A-RXN]]
| + | |
− | * [[RXN-7716]]
| + | |
− | * [[RXN0-5289]]
| + | |
− | * [[1.1.1.211-RXN]]
| + | |
− | * [[RXN0-2044]]
| + | |
− | * [[RXN-18202]]
| + | |
− | * [[IMP-DEHYDROG-RXN]]
| + | |
− | * [[RETINOL-DEHYDROGENASE-RXN]]
| + | |
− | * [[BCor]]
| + | |
− | * [[GLYCOLATE-REDUCTASE-RXN]]
| + | |
− | * [[RXN-18208]]
| + | |
− | * [[2.4.2.31-RXN]]
| + | |
− | * [[RR-BUTANEDIOL-DEHYDROGENASE-RXN]]
| + | |
− | * [[HYDROXYPYRROLINEDEH-RXN]]
| + | |
− | * [[NADH-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN-8629]]
| + | |
− | * [[RXN-12448]]
| + | |
− | * [[RXN-11662]]
| + | |
− | * [[RIBITOL-2-DEHYDROGENASE-RXN]]
| + | |
− | * [[ALCOHOL-DEHYDROG-GENERIC-RXN]]
| + | |
− | * [[L-IDITOL-2-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN-10915]]
| + | |
− | * [[GLUTAMATE-DEHYDROGENASE-RXN]]
| + | |
− | * [[ALCD19]]
| + | |
− | * [[HISTOLDEHYD-RXN]]
| + | |
− | * [[HACD5m]]
| + | |
− | * [[MALATE-DEH-RXN]]
| + | |
− | * [[2KETO-3METHYLVALERATE-RXN]]
| + | |
− | * [[RXN-18200]]
| + | |
− | * [[RXN-7657]]
| + | |
− | * [[RXN-7644]]
| + | |
− | * [[ALCOHOL-DEHYDROG-RXN]]
| + | |
− | * [[RXN-13671]]
| + | |
− | * [[RXN-14102]]
| + | |
− | * [[HBNOm]]
| + | |
− | * [[RXN-1302]]
| + | |
− | * [[RXN-7693]]
| + | |
− | * [[D-LACTALDEHYDE-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN66-350]]
| + | |
− | * [[3-ISOPROPYLMALDEHYDROG-RXN]]
| + | |
− | * [[BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN]]
| + | |
− | * [[GLYCINE-DEHYDROGENASE-RXN]]
| + | |
− | * [[1.1.1.145-RXN]]
| + | |
− | * [[3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN]]
| + | |
− | * [[BADH-RXN]]
| + | |
− | * [[RXN-16133]]
| + | |
− | * [[RXN-18204]]
| + | |
− | * [[GAPOXNPHOSPHN-RXN]]
| + | |
− | * [[RXN0-901]]
| + | |
− | * [[NAD+-ADP-RIBOSYLTRANSFERASE-RXN]]
| + | |
− | * [[FUMARATE-REDUCTASE-NADH-RXN]]
| + | |
− | * [[PGLYCDEHYDROG-RXN]]
| + | |
− | * [[HACD5]]
| + | |
− | * [[RXN-12332]]
| + | |
− | * [[1.3.1.9-RXN]]
| + | |
− | * [[RME295]]
| + | |
− | * [[RXN-18210]]
| + | |
− | * [[MYO-INOSITOL-2-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN-14225]]
| + | |
− | * [[RXN-14224]]
| + | |
− | * [[RXN-13198]]
| + | |
− | * [[R01752]]
| + | |
− | * [[RXN0-276]]
| + | |
− | * [[ACETALD-DEHYDROG-RXN]]
| + | |
− | * [[RXN-14280]]
| + | |
| == External links == | | == External links == |
− | * CAS : 53-84-9
| + | {{#set: right end position=4959}} |
− | * METABOLIGHTS : MTBLC57540
| + | {{#set: transcription direction=POSITIVE}} |
− | * PUBCHEM:
| + | {{#set: left end position=2962}} |
− | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=15938971 15938971]
| + | {{#set: centisome position=45.193775 }} |
− | * HMDB : HMDB00902
| + | {{#set: reaction associated=PROLINE-RACEMASE-RXN}} |
− | * LIGAND-CPD:
| + | {{#set: pathway associated=PWY-6344}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?C00003 C00003]
| + | |
− | * CHEMSPIDER:
| + | |
− | ** [http://www.chemspider.com/Chemical-Structure.10239196.html 10239196]
| + | |
− | * CHEBI:
| + | |
− | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57540 57540]
| + | |
− | * BIGG : nad
| + | |
− | {{#set: smiles=C1(C(=CC=C[N+]=1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O)}} | + | |
− | {{#set: inchi key=InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-M}} | + | |
− | {{#set: common name=NAD+}} | + | |
− | {{#set: molecular weight=662.422 }} | + | |
− | {{#set: common name=NAD+|beta-nicotinamide adenine dinucleotide|coenzyme I|diphosphopyridine nucleotide|diphosphopyridine nucleotide oxidized|nicotinamide adenine dinucleotide|nicotinamide adenine dinucleotide oxidized|NAD-oxidized|NAD-ox|DPN+|DPN-ox|DPN|β-nicotinamide adenine dinucleotide|NAD|β-NAD+}} | + | |
− | {{#set: consumed by=RXN-905|RXN-12490|RXN66-476-CPD-388/NAD/WATER//CPD-8462/NADH/PROTON.40.|RXN66-476-CPD-14719/NAD/WATER//CPD-7830/NADH/PROTON.42.|1.1.1.39-RXN|PREPHENATEDEHYDROG-RXN|ALDDH|RXN-11213|1.5.1.7-RXN|RXN-13158|2.7.1.160-RXN|RXN-12789|3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|PYRIDOXAL-4-DEHYDROGENASE-RXN|R222-RXN|RXN-13414|RXN-12705|RXN-8001|RXN-14249|RXN-17115|RXN66-3|ALDH_im4ac|AMINOBUTDEHYDROG-RXN|RXN-14393|RXN-1884|HISTALDEHYD-RXN|RXN66-353|DHBDEHYD-RXN|RXNQT-4178|1.2.1.25-RXN|RXN-10089|ALDHDEHYDROG-RXN|2-KETO-ADIPATE-DEHYDROG-RXN|RXN-8162|RXN-12693|IMDH|PYRUVDEH-RXN|RXN-11245|RXN-10715|RXNQT-4174|THREODEHYD-RXN|HBCO|RXNQT-4171|RXN-2902|1.2.1.65-RXN|RXN-12750|2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|GLYCOLALD-DEHYDROG-RXN|RXN-37|RXN66-479|OHACYL-COA-DEHYDROG-RXN|NAD-KIN-RXN|RXN66-472|RXN66-476|RXN-16559|UDPGALor|RXN-17786|RXN-17781|1.5.1.9-RXN|RXNQT-4168|RXN-10702|RXN-10703|RXNQT-4165|1.2.1.27-RXN|RXN0-1132|R00476|RXN-10780|RXN-17777|RXN-14116|RXN-12581|RXN-7682|RXN-17794|RXN66-478|RXN-17790|PYRROLINECARBDEHYDROG-RXN|1.8.1.4-RXN|RXN-17798|QUINATE-5-DEHYDROGENASE-RXN|RXN66-342|BNorh|RXN-12507|ALDDHm|RXN-14271|DIMETHUROPORDEHYDROG-RXN|RXN-14275|SSNOm|RXN-7745|RXN-10698|RXN-16136|SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|RXN-14986|BNor|RXN0-5248}}
| + | |
− | {{#set: produced by=RXN1G-248|RXN-9660|RXN-11195|RXN1G-1057|GLUTAMATE-SYNTHASE-NADH-RXN|RXN1G-679|GDRm|RXN-10062|RXN-5424|RXN-11478|RXN-8025|GDRh|1.5.1.20-RXN|RXN1G-509|RXN1G-337|RXN-3661|NODOx|RXN3O-4113|RXN1G-285|R07562|NADHor_2m|ACDHi|RXN1G-488|RXN1G-526|RXN-9659|RXN-9658|RXN-10911|RXN-11482|R4-RXN|RXN-9635|RXN1G-915|ENOYL-ACP-REDUCT-NADH-RXN|RXN1G-196|RXN1G-396|RXN1G-37|RXN-10657|RXN-7694|1.1.1.8-RXN|GLYCERATE-DEHYDROGENASE-RXN|RXN1G-339|RXN0-5330|RXN1G-471|RXN1G-210|GLYCLTD|ALCDHi|RXN-7700|ACDHmi|RXN-7706|ALCDHmi|RXN0-2145|RXN1G-395|RXN1G-299|MTHFO|CYTOCHROME-B5-REDUCTASE-RXN|RXN1G-276|RXN-12997|RXN1G-820|1.6.5.4-RXN|4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|RXN1G-686|RXN-9662|RXN-9663|GDR|RXN-9661|RXN1G-1325|RXN1G-468|RXN-9558|RXN1G-607|RXN1G-171|RXN-12570|RXN-5822|RXN1G-962|RXN-9657|RXN1G-1130|RXN1G-1117|RXN-10661|NITRATE-REDUCTASE-NADH-RXN|RXN1G-193|RXN-8026|RXN-10781|RXN-13417}} | + | |
− | {{#set: reversible reaction associated=1.1.1.255-RXN|HMNOS|MANNPDEHYDROG-RXN|RXN-161|RXN-7719|ALLYSINE-DEHYDROG-RXN|PHENDEHYD-RXN|RXN-18206|D-THREO-ALDOSE-1-DEHYDROGENASE-RXN|NADH-DEHYDROG-A-RXN|RXN-7716|RXN0-5289|1.1.1.211-RXN|RXN0-2044|RXN-18202|IMP-DEHYDROG-RXN|RETINOL-DEHYDROGENASE-RXN|BCor|GLYCOLATE-REDUCTASE-RXN|RXN-18208|2.4.2.31-RXN|RR-BUTANEDIOL-DEHYDROGENASE-RXN|HYDROXYPYRROLINEDEH-RXN|NADH-DEHYDROGENASE-RXN|RXN-8629|RXN-12448|RXN-11662|RIBITOL-2-DEHYDROGENASE-RXN|ALCOHOL-DEHYDROG-GENERIC-RXN|L-IDITOL-2-DEHYDROGENASE-RXN|RXN-10915|GLUTAMATE-DEHYDROGENASE-RXN|ALCD19|HISTOLDEHYD-RXN|HACD5m|MALATE-DEH-RXN|2KETO-3METHYLVALERATE-RXN|RXN-18200|RXN-7657|RXN-7644|ALCOHOL-DEHYDROG-RXN|RXN-13671|RXN-14102|HBNOm|RXN-1302|RXN-7693|D-LACTALDEHYDE-DEHYDROGENASE-RXN|RXN66-350|3-ISOPROPYLMALDEHYDROG-RXN|BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|GLYCINE-DEHYDROGENASE-RXN|1.1.1.145-RXN|3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|BADH-RXN|RXN-16133|RXN-18204|GAPOXNPHOSPHN-RXN|RXN0-901|NAD+-ADP-RIBOSYLTRANSFERASE-RXN|FUMARATE-REDUCTASE-NADH-RXN|PGLYCDEHYDROG-RXN|HACD5|RXN-12332|1.3.1.9-RXN|RME295|RXN-18210|MYO-INOSITOL-2-DEHYDROGENASE-RXN|RXN-14225|RXN-14224|RXN-13198|R01752|RXN0-276|ACETALD-DEHYDROG-RXN|RXN-14280}}
| + | |