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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=BRANCHED-CHAINAMINOTRANSFERLEU-RXN BRANCHED-CHAINAMINOTRANSFERLEU-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=LONG-CHAIN-KETONE LONG-CHAIN-KETONE] == |
− | * direction:
| + | |
− | ** REVERSIBLE
| + | |
| * common name: | | * common name: |
− | ** branched-chain_amino_acid_aminotransferase | + | ** a ketone |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/2.6.1.6 EC-2.6.1.6]
| + | |
− | ** [http://enzyme.expasy.org/EC/2.6.1.42 EC-2.6.1.42]
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| * Synonym(s): | | * Synonym(s): |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
− | ** 1 [[2-KETOGLUTARATE]][c] '''+''' 1 [[LEU]][c] '''<=>''' 1 [[2K-4CH3-PENTANOATE]][c] '''+''' 1 [[GLT]][c]
| + | == Reaction(s) of unknown directionality == |
− | * With common name(s):
| + | * [[RXN-12448]] |
− | ** 1 2-oxoglutarate[c] '''+''' 1 L-leucine[c] '''<=>''' 1 4-methyl-2-oxopentanoate[c] '''+''' 1 L-glutamate[c]
| + | * [[CARBONYL-REDUCTASE-NADPH-RXN]] |
− | | + | |
− | == Genes associated with this reaction == | + | |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * [[Tiso_gene_18403]]
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− | ** [[pantograph]]-[[synechocystis]]
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− | * [[Tiso_gene_14984]]
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− | ** IN-SILICO_ANNOTATION
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− | ***EC-NUMBER
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− | ** EXPERIMENTAL_ANNOTATION
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− | ***EC-NUMBER
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− | ** [[pantograph]]-[[synechocystis]]
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− | ** [[pantograph]]-[[esiliculosus]]
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− | == Pathways == | + | |
− | * [[PWY-7767]], leucine degradation IV: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7767 PWY-7767] | + | |
− | ** '''1''' reactions found over '''5''' reactions in the full pathway
| + | |
− | * [[LEU-DEG2-PWY]], L-leucine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=LEU-DEG2-PWY LEU-DEG2-PWY] | + | |
− | ** '''6''' reactions found over '''6''' reactions in the full pathway
| + | |
− | * [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
| + | |
− | ** '''6''' reactions found over '''6''' reactions in the full pathway
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− | * [[PWY-5076]], L-leucine degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5076 PWY-5076]
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− | ** '''2''' reactions found over '''3''' reactions in the full pathway
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− | == Reconstruction information ==
| + | |
− | * [[orthology]]:
| + | |
− | ** [[pantograph]]:
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− | *** [[synechocystis]]
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− | *** [[esiliculosus]]
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− | * [[manual]]:
| + | |
− | ** [[primary_network]]
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− | * [[annotation]]:
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− | ** [[pathwaytools]]:
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− | *** [[experimental_annotation]]
| + | |
− | *** [[in-silico_annotation]]
| + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=a ketone}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=18321 18321]
| + | {{#set: reversible reaction associated=RXN-12448|CARBONYL-REDUCTASE-NADPH-RXN}} |
− | * LIGAND-RXN:
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− | ** [http://www.genome.jp/dbget-bin/www_bget?R01090 R01090]
| + | |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9PIM6 Q9PIM6]
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− | ** [http://www.uniprot.org/uniprot/P38891 P38891]
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− | ** [http://www.uniprot.org/uniprot/P47176 P47176]
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− | ** [http://www.uniprot.org/uniprot/O86505 O86505]
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− | ** [http://www.uniprot.org/uniprot/O14370 O14370]
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− | ** [http://www.uniprot.org/uniprot/O32954 O32954]
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− | ** [http://www.uniprot.org/uniprot/P0AB80 P0AB80]
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− | {{#set: direction=REVERSIBLE}}
| + | |
− | {{#set: common name=branched-chain_amino_acid_aminotransferase}} | + | |
− | {{#set: ec number=EC-2.6.1.6}} | + | |
− | {{#set: ec number=EC-2.6.1.42}}
| + | |
− | {{#set: gene associated=Tiso_gene_18403|Tiso_gene_14984}}
| + | |
− | {{#set: in pathway=PWY-7767|LEU-DEG2-PWY|LEUSYN-PWY|PWY-5076}}
| + | |
− | {{#set: reconstruction category=orthology}}
| + | |
− | {{#set: reconstruction tool=pantograph}}
| + | |
− | {{#set: reconstruction source=synechocystis|esiliculosus}}
| + | |
− | {{#set: reconstruction category=manual}}
| + | |
− | {{#set: reconstruction source=primary_network}}
| + | |
− | {{#set: reconstruction category=annotation}}
| + | |
− | {{#set: reconstruction tool=pathwaytools}}
| + | |
− | {{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
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