Difference between revisions of "Thiopurines"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=UBIQUITIN--PROTEIN-LIGASE-RXN UBIQUITIN--PROTEIN-LIGASE-RXN] == * direction: ** LEFT-TO-RIGHT * com...")
(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Thiopurines Thiopurines] == * common name: ** a thiopurine * Synonym(s): == Reaction(s) known...")
 
(One intermediate revision by the same user not shown)
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[[Category:Reaction]]
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[[Category:Metabolite]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=UBIQUITIN--PROTEIN-LIGASE-RXN UBIQUITIN--PROTEIN-LIGASE-RXN] ==
+
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Thiopurines Thiopurines] ==
* direction:
+
** LEFT-TO-RIGHT
+
 
* common name:
 
* common name:
** ORF
+
** a thiopurine
** probable_e3_ubiquitin-protein_ligase_herc4_isoform_x10
+
** peptidyl-prolyl_cis-trans_isomerase-like_2
+
** low_quality_protein:_e3_ubiquitin-protein_ligase_herc2-like
+
** e3_ubiquitin_ligase
+
** zinc_finger_protein
+
** o_ubiquitin_protein_ligase_e3a
+
** f-box_only_protein_11
+
** stackhouse_genomicscaffold_453
+
** rab_family_gtpase
+
** ubiquitin-protein_ligase
+
** ubiquitin_protein_ligase
+
** secretion-regulating_guanine_nucleotide_exchange
+
** zinc_n-recogninwd40-like
+
** auxin_transport_protein_isoform_2
+
** f-box_lrr-repeat_protein_2
+
** brca1-associated_ring_domain_protein_1
+
** ankyrin_repeatdomain-containingprotein-50partial
+
** ubiquitin-
+
** phosphoglycerate_mutase_family_protein
+
** wd_sam_and_u-box_domain_containing_1
+
** anaphase_promoting_complex_subunit_11
+
** tnf_receptor-associated_factor
+
** e3_isg15--protein_ligase_herc6
+
** hrd1-like_protein
+
** os06g0159400_protein
+
** f-box_lrr-repeat_protein
+
** rni-like_protein
+
** hect_e3_ubiquitin_ligase
+
** regulator_of_chromosome_condensation_rcc1
+
** probable_e3_ubiquitin-protein_ligase_herc4
+
* ec number:
+
** [http://enzyme.expasy.org/EC/6.2.1.45 EC-6.2.1.45]
+
 
* Synonym(s):
 
* Synonym(s):
  
== Reaction Formula ==
+
== Reaction(s) known to consume the compound ==
* With identifiers:
+
== Reaction(s) known to produce the compound ==
** 1 [[Ubiquitin-activating-protein-E1-L-cys]][c] '''+''' 1 [[Ubiquitin-C-Terminal-Glycine]][c] '''+''' 1 [[ATP]][c] '''=>''' 1 [[AMP]][c] '''+''' 1 [[PPI]][c] '''+''' 1 [[S-ubiquitinyl-UAP-E1-L-cysteine]][c]
+
== Reaction(s) of unknown directionality ==
* With common name(s):
+
* [[6MPURt]]
** 1 an [E1 ubiquitin-activating enzyme]-L-cysteine[c] '''+''' 1 a [ubiquitin] C-terminal glycine[c] '''+''' 1 ATP[c] '''=>''' 1 AMP[c] '''+''' 1 diphosphate[c] '''+''' 1 an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine[c]
+
 
+
== Genes associated with this reaction  ==
+
Genes have been associated with this reaction based on different elements listed below.
+
* [[Tiso_gene_7506]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17194]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_6901]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_2802]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_7308]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_9662]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_4585]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_3080]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1426]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_8637]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_13243]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_2815]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1427]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_2226]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_5622]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_16642]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1592]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_18824]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_7779]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_18752]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_5776]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17030]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_9666]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_17195]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_14181]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_6910]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1588]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_8483]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1587]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17517]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_8801]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1586]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_19647]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_11148]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_3211]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_4569]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_6902]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1590]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_15624]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_11407]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_14567]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_15214]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_5502]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17196]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_7719]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_10888]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_12627]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_1583]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_8636]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_7955]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1593]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_8048]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17004]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_12348]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1335]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_1591]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_14360]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_12029]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_9575]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_4461]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_16166]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_14182]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1584]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_558]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_13619]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_557]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_4966]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_3418]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_12309]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_3081]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_15097]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_10524]]
+
** [[pantograph]]-[[esiliculosus]]
+
* [[Tiso_gene_1589]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_16913]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17112]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1253]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_3210]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1582]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_4484]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_4094]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_6903]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_3419]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_6946]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_14650]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_4460]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17423]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_17363]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
* [[Tiso_gene_1585]]
+
** IN-SILICO_ANNOTATION
+
***EC-NUMBER
+
== Pathways  ==
+
* [[PWY-7511]], protein ubiquitylation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7511 PWY-7511]
+
** '''9''' reactions found over '''9''' reactions in the full pathway
+
== Reconstruction information  ==
+
* Category: [[orthology]]
+
** Source: [[orthology-esiliculosus]]
+
*** Tool: [[pantograph]]
+
* Category: [[annotation]]
+
** Source: [[annotation-in-silico_annotation]]
+
*** Tool: [[pathwaytools]]
+
 
== External links  ==
 
== External links  ==
* LIGAND-RXN:
+
{{#set: common name=a thiopurine}}
** [http://www.genome.jp/dbget-bin/www_bget?R03876 R03876]
+
{{#set: reversible reaction associated=6MPURt}}
* UNIPROT:
+
** [http://www.uniprot.org/uniprot/P22314 P22314]
+
** [http://www.uniprot.org/uniprot/P49459 P49459]
+
** [http://www.uniprot.org/uniprot/P62256 P62256]
+
** [http://www.uniprot.org/uniprot/P63146 P63146]
+
** [http://www.uniprot.org/uniprot/P28263 P28263]
+
** [http://www.uniprot.org/uniprot/Q02053 Q02053]
+
** [http://www.uniprot.org/uniprot/P62257 P62257]
+
** [http://www.uniprot.org/uniprot/P61088 P61088]
+
** [http://www.uniprot.org/uniprot/P63279 P63279]
+
** [http://www.uniprot.org/uniprot/P19812 P19812]
+
** [http://www.uniprot.org/uniprot/P21734 P21734]
+
** [http://www.uniprot.org/uniprot/P25869 P25869]
+
** [http://www.uniprot.org/uniprot/P31254 P31254]
+
** [http://www.uniprot.org/uniprot/P15731 P15731]
+
** [http://www.uniprot.org/uniprot/P15732 P15732]
+
** [http://www.uniprot.org/uniprot/P29340 P29340]
+
** [http://www.uniprot.org/uniprot/P35133 P35133]
+
** [http://www.uniprot.org/uniprot/P35134 P35134]
+
** [http://www.uniprot.org/uniprot/P35132 P35132]
+
** [http://www.uniprot.org/uniprot/P33296 P33296]
+
** [http://www.uniprot.org/uniprot/P22515 P22515]
+
** [http://www.uniprot.org/uniprot/P39940 P39940]
+
** [http://www.uniprot.org/uniprot/P42748 P42748]
+
** [http://www.uniprot.org/uniprot/P42750 P42750]
+
** [http://www.uniprot.org/uniprot/P42749 P42749]
+
** [http://www.uniprot.org/uniprot/P42747 P42747]
+
** [http://www.uniprot.org/uniprot/P50623 P50623]
+
** [http://www.uniprot.org/uniprot/Q42973 Q42973]
+
** [http://www.uniprot.org/uniprot/P40984 P40984]
+
** [http://www.uniprot.org/uniprot/Q92462 Q92462]
+
** [http://www.uniprot.org/uniprot/Q42540 Q42540]
+
** [http://www.uniprot.org/uniprot/P93028 P93028]
+
** [http://www.uniprot.org/uniprot/P93393 P93393]
+
** [http://www.uniprot.org/uniprot/P31252 P31252]
+
** [http://www.uniprot.org/uniprot/P52486 P52486]
+
** [http://www.uniprot.org/uniprot/Q9YGM6 Q9YGM6]
+
** [http://www.uniprot.org/uniprot/O42646 O42646]
+
** [http://www.uniprot.org/uniprot/O15979 O15979]
+
** [http://www.uniprot.org/uniprot/P23566 P23566]
+
** [http://www.uniprot.org/uniprot/Q96PU5 Q96PU5]
+
** [http://www.uniprot.org/uniprot/P27949 P27949]
+
{{#set: direction=LEFT-TO-RIGHT}}
+
{{#set: common name=ORF}}
+
{{#set: common name=probable_e3_ubiquitin-protein_ligase_herc4_isoform_x10}}
+
{{#set: common name=peptidyl-prolyl_cis-trans_isomerase-like_2}}
+
{{#set: common name=low_quality_protein:_e3_ubiquitin-protein_ligase_herc2-like}}
+
{{#set: common name=e3_ubiquitin_ligase}}
+
{{#set: common name=zinc_finger_protein}}
+
{{#set: common name=o_ubiquitin_protein_ligase_e3a}}
+
{{#set: common name=f-box_only_protein_11}}
+
{{#set: common name=stackhouse_genomicscaffold_453}}
+
{{#set: common name=rab_family_gtpase}}
+
{{#set: common name=ubiquitin-protein_ligase}}
+
{{#set: common name=ubiquitin_protein_ligase}}
+
{{#set: common name=secretion-regulating_guanine_nucleotide_exchange}}
+
{{#set: common name=zinc_n-recogninwd40-like}}
+
{{#set: common name=auxin_transport_protein_isoform_2}}
+
{{#set: common name=f-box_lrr-repeat_protein_2}}
+
{{#set: common name=brca1-associated_ring_domain_protein_1}}
+
{{#set: common name=ankyrin_repeatdomain-containingprotein-50partial}}
+
{{#set: common name=ubiquitin-}}
+
{{#set: common name=phosphoglycerate_mutase_family_protein}}
+
{{#set: common name=wd_sam_and_u-box_domain_containing_1}}
+
{{#set: common name=anaphase_promoting_complex_subunit_11}}
+
{{#set: common name=tnf_receptor-associated_factor}}
+
{{#set: common name=e3_isg15--protein_ligase_herc6}}
+
{{#set: common name=hrd1-like_protein}}
+
{{#set: common name=os06g0159400_protein}}
+
{{#set: common name=f-box_lrr-repeat_protein}}
+
{{#set: common name=rni-like_protein}}
+
{{#set: common name=hect_e3_ubiquitin_ligase}}
+
{{#set: common name=regulator_of_chromosome_condensation_rcc1}}
+
{{#set: common name=probable_e3_ubiquitin-protein_ligase_herc4}}
+
{{#set: ec number=EC-6.2.1.45}}
+
{{#set: gene associated=Tiso_gene_7506|Tiso_gene_17194|Tiso_gene_6901|Tiso_gene_2802|Tiso_gene_7308|Tiso_gene_9662|Tiso_gene_4585|Tiso_gene_3080|Tiso_gene_1426|Tiso_gene_8637|Tiso_gene_13243|Tiso_gene_2815|Tiso_gene_1427|Tiso_gene_2226|Tiso_gene_5622|Tiso_gene_16642|Tiso_gene_1592|Tiso_gene_18824|Tiso_gene_7779|Tiso_gene_18752|Tiso_gene_5776|Tiso_gene_17030|Tiso_gene_9666|Tiso_gene_17195|Tiso_gene_14181|Tiso_gene_6910|Tiso_gene_1588|Tiso_gene_8483|Tiso_gene_1587|Tiso_gene_17517|Tiso_gene_8801|Tiso_gene_1586|Tiso_gene_19647|Tiso_gene_11148|Tiso_gene_3211|Tiso_gene_4569|Tiso_gene_6902|Tiso_gene_1590|Tiso_gene_15624|Tiso_gene_11407|Tiso_gene_14567|Tiso_gene_15214|Tiso_gene_5502|Tiso_gene_17196|Tiso_gene_7719|Tiso_gene_10888|Tiso_gene_12627|Tiso_gene_1583|Tiso_gene_8636|Tiso_gene_7955|Tiso_gene_1593|Tiso_gene_8048|Tiso_gene_17004|Tiso_gene_12348|Tiso_gene_1335|Tiso_gene_1591|Tiso_gene_14360|Tiso_gene_12029|Tiso_gene_9575|Tiso_gene_4461|Tiso_gene_16166|Tiso_gene_14182|Tiso_gene_1584|Tiso_gene_558|Tiso_gene_13619|Tiso_gene_557|Tiso_gene_4966|Tiso_gene_3418|Tiso_gene_12309|Tiso_gene_3081|Tiso_gene_15097|Tiso_gene_10524|Tiso_gene_1589|Tiso_gene_16913|Tiso_gene_17112|Tiso_gene_1253|Tiso_gene_3210|Tiso_gene_1582|Tiso_gene_4484|Tiso_gene_4094|Tiso_gene_6903|Tiso_gene_3419|Tiso_gene_6946|Tiso_gene_14650|Tiso_gene_4460|Tiso_gene_17423|Tiso_gene_17363|Tiso_gene_1585}}
+
{{#set: in pathway=PWY-7511}}
+
{{#set: reconstruction category=orthology|annotation}}
+
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
+

Latest revision as of 20:10, 21 March 2018

Metabolite Thiopurines

  • common name:
    • a thiopurine
  • Synonym(s):

Reaction(s) known to consume the compound

Reaction(s) known to produce the compound

Reaction(s) of unknown directionality

External links