Difference between revisions of "RXN-12124"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=METHYLENE-THF METHYLENE-THF] == * smiles: ** C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12124 RXN-12124] == * direction: ** LEFT-TO-RIGHT * common name: ** 3-oxo-5-alpha-steroid_4-deh...")
 
(One intermediate revision by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=METHYLENE-THF METHYLENE-THF] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12124 RXN-12124] ==
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* smiles:
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* direction:
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** C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O))C[CH]34)))
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=QYNUQALWYRSVHF-OLZOCXBDSA-L
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* common name:
 
* common name:
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** 5,10-methylenetetrahydropteroyl mono-L-glutamate
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** 3-oxo-5-alpha-steroid_4-dehydrogenase
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* molecular weight:
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* ec number:
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** 455.429   
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** [http://enzyme.expasy.org/EC/1.3.99.5 EC-1.3.99.5]
 
* Synonym(s):
 
* Synonym(s):
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** N5,N10-methylenetetrahydrofolate mono-L-glutamate
 
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** 5,10-methylenetetrahydrofolate mono-L-glutamate
 
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** 5,10-methylene-H4PteGlu1
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[MTMOHT]]
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* With identifiers:
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* [[MTHFO]]
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** 1 [[Acceptor]][c] '''+''' 1 [[CPD-342]][c] '''=>''' 1 [[Donor-H2]][c] '''+''' 1 [[ANDROST4ENE]][c]
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* [[MTHFO_nadp]]
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* With common name(s):
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* [[R01226]]
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** 1 an oxidized electron acceptor[c] '''+''' 1 5α-androstane-3,17-dione[c] '''=>''' 1 a reduced electron acceptor[c] '''+''' 1 androst-4-ene-3,17-dione[c]
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== Reaction(s) known to produce the compound ==
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== Reaction(s) of unknown directionality ==
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== Genes associated with this reaction  ==
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* [[MTHFor_nadp]]
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Genes have been associated with this reaction based on different elements listed below.
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* [[MLTHFtm]]
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* Gene: [[Tiso_gene_14327]]
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* [[R01220]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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== Pathways  ==
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* [[PWY-6943]], testosterone and androsterone degradation to androstendione: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6943 PWY-6943]
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** '''1''' reactions found over '''3''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* METABOLIGHTS : MTBLC15636
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{{#set: direction=LEFT-TO-RIGHT}}
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* PUBCHEM:
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{{#set: common name=3-oxo-5-alpha-steroid_4-dehydrogenase}}
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9548565 9548565]
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{{#set: ec number=EC-1.3.99.5}}
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* HMDB : HMDB01533
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{{#set: gene associated=Tiso_gene_14327}}
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* LIGAND-CPD:
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{{#set: in pathway=PWY-6943}}
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** [http://www.genome.jp/dbget-bin/www_bget?C00143 C00143]
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{{#set: reconstruction category=annotation}}
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* CHEMSPIDER:
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{{#set: reconstruction source=annotation-in-silico_annotation}}
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** [http://www.chemspider.com/Chemical-Structure.7827491.html 7827491]
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{{#set: reconstruction tool=pathwaytools}}
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* CHEBI:
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=15636 15636]
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* BIGG : mlthf
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{{#set: smiles=C4(NC1(N=C(N)NC(=O)C=1N3(CN(C2(=CC=C(C=C2)C(=O)NC(CCC([O-])=O)C([O-])=O))C[CH]34)))}}
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{{#set: inchi key=InChIKey=QYNUQALWYRSVHF-OLZOCXBDSA-L}}
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{{#set: common name=5,10-methylenetetrahydropteroyl mono-L-glutamate}}
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{{#set: molecular weight=455.429    }}
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{{#set: common name=N5,N10-methylenetetrahydrofolate mono-L-glutamate|5,10-methylenetetrahydrofolate mono-L-glutamate|5,10-methylene-H4PteGlu1}}
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{{#set: consumed by=MTMOHT|MTHFO|MTHFO_nadp|R01226}}
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{{#set: reversible reaction associated=MTHFor_nadp|MLTHFtm|R01220}}
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Latest revision as of 21:13, 21 March 2018

Reaction RXN-12124

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-oxo-5-alpha-steroid_4-dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 an oxidized electron acceptor[c] + 1 5α-androstane-3,17-dione[c] => 1 a reduced electron acceptor[c] + 1 androst-4-ene-3,17-dione[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6943, testosterone and androsterone degradation to androstendione: PWY-6943
    • 1 reactions found over 3 reactions in the full pathway

Reconstruction information

External links

Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=RXN-12124&oldid=46955"