Difference between revisions of "1.2.4.4-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN] == * direction: ** LEF...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.4.4-RXN 1.2.4.4-RXN] == * direction: ** REVERSIBLE * common name: ** 3-methyl-2-oxobutanoate_de...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=1.2.4.4-RXN 1.2.4.4-RXN] ==
 
* direction:
 
* direction:
−
** LEFT-TO-RIGHT
+
** REVERSIBLE
 
* common name:
 
* common name:
−
** myo-inositol-1-phosphate_synthase
+
** 3-methyl-2-oxobutanoate_dehydrogenase
 +
** 2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/5.5.1.4 EC-5.5.1.4]
+
** [http://enzyme.expasy.org/EC/1.2.4.4 EC-1.2.4.4]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[D-glucopyranose-6-phosphate]][c] '''=>''' 1 [[1-L-MYO-INOSITOL-1-P]][c]
+
** 1 [[BCAA-dehydrogenase-lipoyl]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''+''' 1 [[PROTON]][c] '''<=>''' 1 [[BCAA-dehydrogenase-2MP-DH-lipoyl]][c] '''+''' 1 [[CARBON-DIOXIDE]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 D-glucopyranose 6-phosphate[c] '''=>''' 1 1D-myo-inositol 3-monophosphate[c]
+
** 1 an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''+''' 1 H+[c] '''<=>''' 1 an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylpropanoyl]dihydrolipoyl-L-lysine[c] '''+''' 1 CO2[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Tiso_gene_7167]]
+
* Gene: [[Tiso_gene_11793]]
−
** IN-SILICO_ANNOTATION
+
** Source: [[annotation-in-silico_annotation]]
−
***EC-NUMBER
+
*** Assignment: AUTOMATED-NAME-MATCH
−
** [[pantograph]]-[[esiliculosus]]
+
* Gene: [[Tiso_gene_3260]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_18084]]
 +
** Source: [[orthology-esiliculosus]]
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-2301]], myo-inositol biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2301 PWY-2301]
+
* [[PWY-5046]], 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5046 PWY-5046]
−
** '''2''' reactions found over '''2''' reactions in the full pathway
+
** '''3''' reactions found over '''3''' reactions in the full pathway
−
* [[PWY-4661]], 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza): [http://metacyc.org/META/NEW-IMAGE?object=PWY-4661 PWY-4661]
+
−
** '''3''' reactions found over '''7''' reactions in the full pathway
+
−
* [[PWY-6580]], phosphatidylinositol biosynthesis I (bacteria): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6580 PWY-6580]
+
−
** '''1''' reactions found over '''3''' reactions in the full pathway
+
−
* [[PWY-6664]], di-myo-inositol phosphate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6664 PWY-6664]
+
−
** '''1''' reactions found over '''4''' reactions in the full pathway
+
−
* [[PWY1G-0]], mycothiol biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY1G-0 PWY1G-0]
+
−
** '''1''' reactions found over '''6''' reactions in the full pathway
+
−
* [[PWY-6372]], 1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6372 PWY-6372]
+
−
** '''3''' reactions found over '''7''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
Line 39: Line 36:
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
−
** Source: [[annotation-experimental_annotation]]
 
−
*** Tool: [[pathwaytools]]
 
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-experimental_annotation]]
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* RHEA:
 
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10716 10716]
 
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R07324 R07324]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01701 R01701]
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/P42800 P42800]
+
** [http://www.uniprot.org/uniprot/P21839 P21839]
−
** [http://www.uniprot.org/uniprot/P42802 P42802]
+
** [http://www.uniprot.org/uniprot/P21953 P21953]
−
** [http://www.uniprot.org/uniprot/P42803 P42803]
+
** [http://www.uniprot.org/uniprot/P37940 P37940]
−
** [http://www.uniprot.org/uniprot/Q9FPK7 Q9FPK7]
+
** [http://www.uniprot.org/uniprot/Q9PK54 Q9PK54]
−
** [http://www.uniprot.org/uniprot/O65195 O65195]
+
** [http://www.uniprot.org/uniprot/P37941 P37941]
−
** [http://www.uniprot.org/uniprot/P42801 P42801]
+
** [http://www.uniprot.org/uniprot/P11178 P11178]
−
** [http://www.uniprot.org/uniprot/Q96348 Q96348]
+
** [http://www.uniprot.org/uniprot/P12694 P12694]
−
** [http://www.uniprot.org/uniprot/Q41107 Q41107]
+
** [http://www.uniprot.org/uniprot/P09061 P09061]
−
** [http://www.uniprot.org/uniprot/Q40271 Q40271]
+
** [http://www.uniprot.org/uniprot/P09060 P09060]
−
** [http://www.uniprot.org/uniprot/Q18664 Q18664]
+
** [http://www.uniprot.org/uniprot/P11960 P11960]
−
** [http://www.uniprot.org/uniprot/Q9LX12 Q9LX12]
+
** [http://www.uniprot.org/uniprot/O84344 O84344]
−
{{#set: direction=LEFT-TO-RIGHT}}
+
** [http://www.uniprot.org/uniprot/Q9Z9E8 Q9Z9E8]
−
{{#set: common name=myo-inositol-1-phosphate_synthase}}
+
** [http://www.uniprot.org/uniprot/Q9I1M2 Q9I1M2]
−
{{#set: ec number=EC-5.5.1.4}}
+
** [http://www.uniprot.org/uniprot/P35738 P35738]
−
{{#set: gene associated=Tiso_gene_7167}}
+
** [http://www.uniprot.org/uniprot/P50136 P50136]
−
{{#set: in pathway=PWY-2301|PWY-4661|PWY-6580|PWY-6664|PWY1G-0|PWY-6372}}
+
** [http://www.uniprot.org/uniprot/O48615 O48615]
 +
** [http://www.uniprot.org/uniprot/O03849 O03849]
 +
** [http://www.uniprot.org/uniprot/Q53592 Q53592]
 +
** [http://www.uniprot.org/uniprot/Q53593 Q53593]
 +
** [http://www.uniprot.org/uniprot/O82450 O82450]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=3-methyl-2-oxobutanoate_dehydrogenase}}
 +
{{#set: common name=2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial}}
 +
{{#set: ec number=EC-1.2.4.4}}
 +
{{#set: gene associated=Tiso_gene_11793|Tiso_gene_3260|Tiso_gene_18084}}
 +
{{#set: in pathway=PWY-5046}}
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction source=annotation-experimental_annotation|annotation-in-silico_annotation|orthology-esiliculosus}}
+
{{#set: reconstruction source=annotation-in-silico_annotation|annotation-experimental_annotation|orthology-esiliculosus}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:20, 21 March 2018

Reaction 1.2.4.4-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • 3-methyl-2-oxobutanoate_dehydrogenase
    • 2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5046, 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: PWY-5046
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links





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