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| [[Category:Reaction]] | | [[Category:Reaction]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=4-COUMARATE--COA-LIGASE-RXN 4-COUMARATE--COA-LIGASE-RXN] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12753 RXN-12753] == |
| * direction: | | * direction: |
| ** LEFT-TO-RIGHT | | ** LEFT-TO-RIGHT |
− | * ec number:
| |
− | ** [http://enzyme.expasy.org/EC/6.2.1.12 EC-6.2.1.12]
| |
| * Synonym(s): | | * Synonym(s): |
| | | |
| == Reaction Formula == | | == Reaction Formula == |
| * With identifiers: | | * With identifiers: |
− | ** 1 [[ATP]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[COUMARATE]][c] '''=>''' 1 [[P-COUMAROYL-COA]][c] '''+''' 1 [[PPI]][c] '''+''' 1 [[AMP]][c] | + | ** 1 [[WATER]][c] '''+''' 1 [[NADH]][c] '''=>''' 1 [[CPD-653]][c] |
| * With common name(s): | | * With common name(s): |
− | ** 1 ATP[c] '''+''' 1 coenzyme A[c] '''+''' 1 4-coumarate[c] '''=>''' 1 4-coumaroyl-CoA[c] '''+''' 1 diphosphate[c] '''+''' 1 AMP[c] | + | ** 1 H2O[c] '''+''' 1 NADH[c] '''=>''' 1 (S)-NADHX[c] |
| | | |
| == Genes associated with this reaction == | | == Genes associated with this reaction == |
− | Genes have been associated with this reaction based on different elements listed below.
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− | * Gene: [[Tiso_gene_12275]]
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− | ** Source: [[orthology-athaliana]]
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− | ** Source: [[orthology-esiliculosus]]
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− | * Gene: [[Tiso_gene_14183]]
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− | ** Source: [[orthology-esiliculosus]]
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| == Pathways == | | == Pathways == |
− | * [[PWY-6920]], 6-gingerol analog biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6920 PWY-6920] | + | * [[PWY-6938]], NADH repair: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6938 PWY-6938] |
− | ** '''5''' reactions found over '''6''' reactions in the full pathway
| + | |
− | * [[PWY-6435]], 4-hydroxybenzoate biosynthesis V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6435 PWY-6435]
| + | |
− | ** '''4''' reactions found over '''5''' reactions in the full pathway
| + | |
− | * [[PWY-7398]], coumarins biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7398 PWY-7398]
| + | |
− | ** '''3''' reactions found over '''13''' reactions in the full pathway
| + | |
− | * [[PWY-7046]], 4-coumarate degradation (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7046 PWY-7046]
| + | |
− | ** '''2''' reactions found over '''6''' reactions in the full pathway
| + | |
− | * [[PWY-361]], phenylpropanoid biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-361 PWY-361]
| + | |
− | ** '''7''' reactions found over '''15''' reactions in the full pathway
| + | |
− | * [[PWY-7397]], naringenin biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7397 PWY-7397]
| + | |
| ** '''2''' reactions found over '''4''' reactions in the full pathway | | ** '''2''' reactions found over '''4''' reactions in the full pathway |
− | * [[PWY-6320]], phaselate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6320 PWY-6320]
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− | ** '''1''' reactions found over '''5''' reactions in the full pathway
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− | * [[PWY1F-FLAVSYN]], flavonoid biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY1F-FLAVSYN PWY1F-FLAVSYN]
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− | ** '''4''' reactions found over '''5''' reactions in the full pathway
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− | * [[PWY-5754]], 4-hydroxybenzoate biosynthesis I (eukaryotes): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5754 PWY-5754]
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− | ** '''2''' reactions found over '''6''' reactions in the full pathway
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− | * [[PWY-5135]], xanthohumol biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5135 PWY-5135]
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− | ** '''1''' reactions found over '''4''' reactions in the full pathway
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− | * [[PWY-6982]], umbelliferone biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6982 PWY-6982]
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− | ** '''1''' reactions found over '''3''' reactions in the full pathway
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| == Reconstruction information == | | == Reconstruction information == |
− | * Category: [[orthology]] | + | * Category: [[annotation]] |
− | ** Source: [[orthology-athaliana]] | + | ** Source: [[annotation-in-silico_annotation]] |
− | *** Tool: [[pantograph]] | + | *** Tool: [[pathwaytools]] |
− | ** Source: [[orthology-esiliculosus]] | + | ** Source: [[annotation-experimental_annotation]] |
− | *** Tool: [[pantograph]] | + | *** Tool: [[pathwaytools]] |
| == External links == | | == External links == |
− | * RHEA:
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− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19641 19641]
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− | * LIGAND-RXN:
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− | ** [http://www.genome.jp/dbget-bin/www_bget?R01616 R01616]
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− | * UNIPROT:
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− | ** [http://www.uniprot.org/uniprot/P31684 P31684]
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− | ** [http://www.uniprot.org/uniprot/P31685 P31685]
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− | ** [http://www.uniprot.org/uniprot/Q9SWH8 Q9SWH8]
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− | ** [http://www.uniprot.org/uniprot/Q9SWH7 Q9SWH7]
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− | ** [http://www.uniprot.org/uniprot/P17814 P17814]
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− | ** [http://www.uniprot.org/uniprot/P31687 P31687]
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− | ** [http://www.uniprot.org/uniprot/Q8S5C2 Q8S5C2]
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− | ** [http://www.uniprot.org/uniprot/P14912 P14912]
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− | ** [http://www.uniprot.org/uniprot/P14913 P14913]
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− | ** [http://www.uniprot.org/uniprot/P31686 P31686]
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− | ** [http://www.uniprot.org/uniprot/Q42524 Q42524]
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− | ** [http://www.uniprot.org/uniprot/Q42943 Q42943]
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− | ** [http://www.uniprot.org/uniprot/Q42982 Q42982]
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− | ** [http://www.uniprot.org/uniprot/P93360 P93360]
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− | ** [http://www.uniprot.org/uniprot/P93361 P93361]
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− | ** [http://www.uniprot.org/uniprot/O24146 O24146]
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− | ** [http://www.uniprot.org/uniprot/O48868 O48868]
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− | ** [http://www.uniprot.org/uniprot/O48869 O48869]
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− | ** [http://www.uniprot.org/uniprot/O81139 O81139]
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− | ** [http://www.uniprot.org/uniprot/O81140 O81140]
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− | ** [http://www.uniprot.org/uniprot/P41636 P41636]
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| {{#set: direction=LEFT-TO-RIGHT}} | | {{#set: direction=LEFT-TO-RIGHT}} |
− | {{#set: ec number=EC-6.2.1.12}}
| + | {{#set: in pathway=PWY-6938}} |
− | {{#set: gene associated=Tiso_gene_12275|Tiso_gene_14183}}
| + | {{#set: reconstruction category=annotation}} |
− | {{#set: in pathway=PWY-6920|PWY-6435|PWY-7398|PWY-7046|PWY-361|PWY-7397|PWY-6320|PWY1F-FLAVSYN|PWY-5754|PWY-5135|PWY-6982}} | + | {{#set: reconstruction source=annotation-in-silico_annotation|annotation-experimental_annotation}} |
− | {{#set: reconstruction category=orthology}} | + | {{#set: reconstruction tool=pathwaytools}} |
− | {{#set: reconstruction source=orthology-athaliana|orthology-esiliculosus}} | + | |
− | {{#set: reconstruction tool=pantograph}} | + | |