Difference between revisions of "CHOLESTENONE-5-ALPHA-REDUCTASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HEXANOYL-COA HEXANOYL-COA] == * smiles: ** CCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(OP(=O)...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=CHOLESTENONE-5-ALPHA-REDUCTASE-RXN CHOLESTENONE-5-ALPHA-REDUCTASE-RXN] == * direction: ** REVERSIBL...")
 
(3 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HEXANOYL-COA HEXANOYL-COA] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=CHOLESTENONE-5-ALPHA-REDUCTASE-RXN CHOLESTENONE-5-ALPHA-REDUCTASE-RXN] ==
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* smiles:
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* direction:
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** CCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-]
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** REVERSIBLE
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* inchi key:
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** InChIKey=OEXFMSFODMQEPE-HDRQGHTBSA-J
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* common name:
 
* common name:
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** hexanoyl-CoA
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** 3-oxo-5-alpha-steroid_4-dehydrogenase
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* molecular weight:
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* ec number:
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** 861.647   
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** [http://enzyme.expasy.org/EC/1.3.1.22 EC-1.3.1.22]
 
* Synonym(s):
 
* Synonym(s):
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** hexanoyl-coenzyme A
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** 3-oxosteroid Δ4-dehydrogenase
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** Δ4-3-ketosteroid 5α-oxidoreductase
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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== Reaction(s) of unknown directionality ==
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** 1 [[CPD-1081]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[CPD-323]][c] '''+''' 1 [[NADPH]][c] '''+''' 1 [[PROTON]][c]
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* [[RXN-14278]]
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* With common name(s):
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* [[RXN-14277]]
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** 1 5&alpha;-cholestan-3-one[c] '''+''' 1 NADP+[c] '''<=>''' 1 cholest-4-en-3-one[c] '''+''' 1 NADPH[c] '''+''' 1 H+[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_14327]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: AUTOMATED-NAME-MATCH
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== Pathways  ==
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 5060-32-2
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* RHEA:
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* METABOLIGHTS : MTBLC27540
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24552 24552]
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* DRUGBANK : DB02563
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* LIGAND-RXN:
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* PUBCHEM:
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** [http://www.genome.jp/dbget-bin/www_bget?R02610 R02610]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=53262356 53262356]
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* UNIPROT:
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* HMDB : HMDB02845
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** [http://www.uniprot.org/uniprot/P31214 P31214]
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P31213 P31213]
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** [http://www.genome.jp/dbget-bin/www_bget?C05270 C05270]
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{{#set: direction=REVERSIBLE}}
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* CHEBI:
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{{#set: common name=3-oxo-5-alpha-steroid_4-dehydrogenase}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=62620 62620]
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{{#set: ec number=EC-1.3.1.22}}
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* BIGG : hxcoa
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{{#set: common name=3-oxosteroid &Delta;4-dehydrogenase|&Delta;4-3-ketosteroid 5&alpha;-oxidoreductase}}
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{{#set: smiles=CCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-]}}
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{{#set: gene associated=Tiso_gene_14327}}
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{{#set: inchi key=InChIKey=OEXFMSFODMQEPE-HDRQGHTBSA-J}}
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{{#set: in pathway=}}
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{{#set: common name=hexanoyl-CoA}}
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{{#set: reconstruction category=annotation}}
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{{#set: molecular weight=861.647    }}
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{{#set: reconstruction source=annotation-in-silico_annotation}}
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{{#set: common name=hexanoyl-coenzyme A}}
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{{#set: reconstruction tool=pathwaytools}}
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{{#set: consumed or produced by=RXN-14278|RXN-14277}}
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Latest revision as of 19:52, 21 March 2018

Reaction CHOLESTENONE-5-ALPHA-REDUCTASE-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • 3-oxo-5-alpha-steroid_4-dehydrogenase
  • ec number:
  • Synonym(s):
    • 3-oxosteroid Δ4-dehydrogenase
    • Δ4-3-ketosteroid 5α-oxidoreductase

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 5α-cholestan-3-one[c] + 1 NADP+[c] <=> 1 cholest-4-en-3-one[c] + 1 NADPH[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links





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