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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACETOOHBUTSYN-RXN ACETOOHBUTSYN-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Aliphatic-L-Amino-Acids Aliphatic-L-Amino-Acids] == |
− | * direction:
| + | |
− | ** LEFT-TO-RIGHT
| + | |
| * common name: | | * common name: |
− | ** 2-aceto-2-hydroxy-butyrate synthase | + | ** an aliphatic L-amino acid |
− | ** Acetolactate synthase catalytic subunit, mitochondrial
| + | |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/2.2.1.6 EC-2.2.1.6]
| + | |
| * Synonym(s): | | * Synonym(s): |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
− | ** 1 [[PROTON]][c] '''+''' 1 [[PYRUVATE]][c] '''+''' 1 [[2-OXOBUTANOATE]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[2-ACETO-2-HYDROXY-BUTYRATE]][c]
| + | == Reaction(s) of unknown directionality == |
− | * With common name(s):
| + | * [[AMINOACYLASE-RXN]] |
− | ** 1 H+[c] '''+''' 1 pyruvate[c] '''+''' 1 2-oxobutanoate[c] '''=>''' 1 CO2[c] '''+''' 1 (S)-2-aceto-2-hydroxybutanoate[c]
| + | |
− | | + | |
− | == Genes associated with this reaction ==
| + | |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * [[Tiso_gene_11362]]
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− | ** EXPERIMENTAL_ANNOTATION
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− | ***EC-NUMBER
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− | == Pathways == | + | |
− | * [[PWY-5103]], L-isoleucine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5103 PWY-5103]
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− | ** '''4''' reactions found over '''7''' reactions in the full pathway
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− | * [[ILEUSYN-PWY]], L-isoleucine biosynthesis I (from threonine): [http://metacyc.org/META/NEW-IMAGE?object=ILEUSYN-PWY ILEUSYN-PWY]
| + | |
− | ** '''7''' reactions found over '''7''' reactions in the full pathway
| + | |
− | * [[PWY-5101]], L-isoleucine biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5101 PWY-5101]
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− | ** '''5''' reactions found over '''8''' reactions in the full pathway
| + | |
− | * [[PWY-5104]], L-isoleucine biosynthesis IV: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5104 PWY-5104]
| + | |
− | ** '''3''' reactions found over '''6''' reactions in the full pathway
| + | |
− | == Reconstruction information == | + | |
− | * [[manual]]: | + | |
− | ** [[primary_network]]
| + | |
− | * [[annotation]]:
| + | |
− | ** [[pathwaytools]]:
| + | |
− | *** [[experimental_annotation]]
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| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=an aliphatic L-amino acid}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=27654 27654]
| + | {{#set: reversible reaction associated=AMINOACYLASE-RXN}} |
− | * LIGAND-RXN:
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− | ** [http://www.genome.jp/dbget-bin/www_bget?R08648 R08648]
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− | * UNIPROT:
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− | ** [http://www.uniprot.org/uniprot/Q59950 Q59950]
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− | ** [http://www.uniprot.org/uniprot/P42463 P42463]
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− | ** [http://www.uniprot.org/uniprot/Q8XAV3 Q8XAV3]
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− | ** [http://www.uniprot.org/uniprot/P27868 P27868]
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− | ** [http://www.uniprot.org/uniprot/P45260 P45260]
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− | ** [http://www.uniprot.org/uniprot/Q57625 Q57625]
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− | ** [http://www.uniprot.org/uniprot/P37251 P37251]
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− | ** [http://www.uniprot.org/uniprot/P45261 P45261]
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− | ** [http://www.uniprot.org/uniprot/O27493 O27493]
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− | ** [http://www.uniprot.org/uniprot/O66759 O66759]
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− | ** [http://www.uniprot.org/uniprot/Q9PHU2 Q9PHU2]
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− | ** [http://www.uniprot.org/uniprot/O05031 O05031]
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− | ** [http://www.uniprot.org/uniprot/Q57725 Q57725]
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− | ** [http://www.uniprot.org/uniprot/Q9PHU1 Q9PHU1]
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− | ** [http://www.uniprot.org/uniprot/Q9JTI1 Q9JTI1]
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− | ** [http://www.uniprot.org/uniprot/Q58077 Q58077]
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− | ** [http://www.uniprot.org/uniprot/O28554 O28554]
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− | ** [http://www.uniprot.org/uniprot/O53554 O53554]
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− | ** [http://www.uniprot.org/uniprot/Q04789 Q04789]
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− | ** [http://www.uniprot.org/uniprot/Q9JRF4 Q9JRF4]
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− | ** [http://www.uniprot.org/uniprot/Q59272 Q59272]
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− | ** [http://www.uniprot.org/uniprot/P27696 P27696]
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− | ** [http://www.uniprot.org/uniprot/Q59498 Q59498]
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− | ** [http://www.uniprot.org/uniprot/Q9RFQ7 Q9RFQ7]
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− | ** [http://www.uniprot.org/uniprot/Q05767 Q05767]
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− | ** [http://www.uniprot.org/uniprot/P40811 P40811]
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− | ** [http://www.uniprot.org/uniprot/P21622 P21622]
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− | ** [http://www.uniprot.org/uniprot/P27818 P27818]
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− | ** [http://www.uniprot.org/uniprot/Q41768 Q41768]
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− | ** [http://www.uniprot.org/uniprot/Q41769 Q41769]
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− | ** [http://www.uniprot.org/uniprot/P69684 P69684]
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− | ** [http://www.uniprot.org/uniprot/P27819 P27819]
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− | ** [http://www.uniprot.org/uniprot/Q9R586 Q9R586]
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− | ** [http://www.uniprot.org/uniprot/Q02137 Q02137]
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− | ** [http://www.uniprot.org/uniprot/Q02140 Q02140]
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− | ** [http://www.uniprot.org/uniprot/P36620 P36620]
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− | ** [http://www.uniprot.org/uniprot/Q42767 Q42767]
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− | ** [http://www.uniprot.org/uniprot/Q42768 Q42768]
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− | ** [http://www.uniprot.org/uniprot/Q49865 Q49865]
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− | ** [http://www.uniprot.org/uniprot/O22547 O22547]
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− | ** [http://www.uniprot.org/uniprot/O49229 O49229]
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− | ** [http://www.uniprot.org/uniprot/O22578 O22578]
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− | ** [http://www.uniprot.org/uniprot/O49210 O49210]
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− | ** [http://www.uniprot.org/uniprot/Q60021 Q60021]
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− | ** [http://www.uniprot.org/uniprot/P07342 P07342]
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− | ** [http://www.uniprot.org/uniprot/P00892 P00892]
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− | ** [http://www.uniprot.org/uniprot/P08142 P08142]
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− | ** [http://www.uniprot.org/uniprot/P0ADF8 P0ADF8]
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− | ** [http://www.uniprot.org/uniprot/P00894 P00894]
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− | ** [http://www.uniprot.org/uniprot/P00893 P00893]
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− | ** [http://www.uniprot.org/uniprot/P17597 P17597]
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− | ** [http://www.uniprot.org/uniprot/P09342 P09342]
| + | |
− | ** [http://www.uniprot.org/uniprot/P09114 P09114]
| + | |
− | ** [http://www.uniprot.org/uniprot/P14874 P14874]
| + | |
− | {{#set: direction=LEFT-TO-RIGHT}}
| + | |
− | {{#set: common name=2-aceto-2-hydroxy-butyrate synthase}} | + | |
− | {{#set: common name=Acetolactate synthase catalytic subunit, mitochondrial}} | + | |
− | {{#set: ec number=EC-2.2.1.6}}
| + | |
− | {{#set: gene associated=Tiso_gene_11362}}
| + | |
− | {{#set: in pathway=PWY-5103|ILEUSYN-PWY|PWY-5101|PWY-5104}}
| + | |
− | {{#set: reconstruction category=manual}}
| + | |
− | {{#set: reconstruction source=primary_network}}
| + | |
− | {{#set: reconstruction category=annotation}}
| + | |
− | {{#set: reconstruction tool=pathwaytools}}
| + | |
− | {{#set: reconstruction source=experimental_annotation}}
| + | |