Difference between revisions of "RXN-12705"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=FORMYL-COA FORMYL-COA] == * smiles: ** CC(C)(C(O)C(=O)NCCC(=O)NCCS[CH]=O)COP(=O)(OP(=O)(OCC1(C(...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12705 RXN-12705] == * direction: ** LEFT-TO-RIGHT * common name: ** hydroxyacyl-coenzyme_a_dehy...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=FORMYL-COA FORMYL-COA] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12705 RXN-12705] ==
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* smiles:
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* direction:
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** CC(C)(C(O)C(=O)NCCC(=O)NCCS[CH]=O)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-]
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** LEFT-TO-RIGHT
 
* common name:
 
* common name:
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** formyl-CoA
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** hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit
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* inchi key:
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** 3-hydroxyacyl-_dehydrogenase
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** InChIKey=SXMOKYXNAPLNCW-GORZOVPNSA-J
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** hydroxyacyl-coenzyme_a_mitochondrial
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* molecular weight:
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* ec number:
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** 791.513   
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** [http://enzyme.expasy.org/EC/1.1.1.35 EC-1.1.1.35]
 
* Synonym(s):
 
* Synonym(s):
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[RXN66-475-CPD-14717//CPD-14719/FORMYL-COA.32.]]
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** 1 [[NAD]][c] '''+''' 1 [[CPD-13694]][c] '''=>''' 1 [[CPD-13695]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[NADH]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 NAD+[c] '''+''' 1 24-hydroxy-3-oxocholest-4-en-26-oyl-CoA[c] '''=>''' 1 3,24-dioxocholest-4-en-26-oyl-CoA[c] '''+''' 1 H+[c] '''+''' 1 NADH[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_18839]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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* Gene: [[Tiso_gene_5857]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-esiliculosus]]
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* Gene: [[Tiso_gene_14026]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-esiliculosus]]
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* Gene: [[Tiso_gene_18838]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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* Gene: [[Tiso_gene_14027]]
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** Source: [[orthology-esiliculosus]]
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* Gene: [[Tiso_gene_14262]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
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== Pathways  ==
 +
* [[PWY-6946]], cholesterol degradation to androstenedione II (cholesterol dehydrogenase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6946 PWY-6946]
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** '''3''' reactions found over '''22''' reactions in the full pathway
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* [[PWY-6945]], cholesterol degradation to androstenedione I (cholesterol oxidase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6945 PWY-6945]
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** '''2''' reactions found over '''17''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-esiliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-experimental_annotation]]
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*** Tool: [[pathwaytools]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* LIGAND-CPD:
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{{#set: direction=LEFT-TO-RIGHT}}
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** [http://www.genome.jp/dbget-bin/www_bget?C00798 C00798]
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{{#set: common name=hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit}}
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* HMDB : HMDB03419
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{{#set: common name=3-hydroxyacyl-_dehydrogenase}}
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* CHEBI:
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{{#set: common name=hydroxyacyl-coenzyme_a_mitochondrial}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57376 57376]
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{{#set: ec number=EC-1.1.1.35}}
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* METABOLIGHTS : MTBLC57376
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{{#set: gene associated=Tiso_gene_18839|Tiso_gene_5857|Tiso_gene_14026|Tiso_gene_18838|Tiso_gene_14027|Tiso_gene_14262}}
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* PUBCHEM:
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{{#set: in pathway=PWY-6946|PWY-6945}}
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=45266602 45266602]
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: smiles=CC(C)(C(O)C(=O)NCCC(=O)NCCS[CH]=O)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-]}}
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{{#set: reconstruction source=annotation-experimental_annotation|annotation-in-silico_annotation|orthology-esiliculosus}}
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{{#set: common name=formyl-CoA}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}
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{{#set: inchi key=InChIKey=SXMOKYXNAPLNCW-GORZOVPNSA-J}}
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{{#set: molecular weight=791.513    }}
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{{#set: produced by=RXN66-475-CPD-14717//CPD-14719/FORMYL-COA.32.}}
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Latest revision as of 20:59, 21 March 2018

Reaction RXN-12705

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit
    • 3-hydroxyacyl-_dehydrogenase
    • hydroxyacyl-coenzyme_a_mitochondrial
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NAD+[c] + 1 24-hydroxy-3-oxocholest-4-en-26-oyl-CoA[c] => 1 3,24-dioxocholest-4-en-26-oyl-CoA[c] + 1 H+[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
    • 3 reactions found over 22 reactions in the full pathway
  • PWY-6945, cholesterol degradation to androstenedione I (cholesterol oxidase): PWY-6945
    • 2 reactions found over 17 reactions in the full pathway

Reconstruction information

External links

Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=RXN-12705&oldid=45119"