Difference between revisions of "RXN-13294"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=apo-Transcarboxylases apo-Transcarboxylases] == * common name: ** an apo-[methylmalonyl-CoA:pyr...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYROXINE-DEIODINASE-RXN THYROXINE-DEIODINASE-RXN] == * direction: ** LEFT-TO-RIGHT * common name:...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=apo-Transcarboxylases apo-Transcarboxylases] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYROXINE-DEIODINASE-RXN THYROXINE-DEIODINASE-RXN] ==
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* direction:
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** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** an apo-[methylmalonyl-CoA:pyruvate carboxytransferase]
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** type_i_iodothyronine_deiodinase
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* ec number:
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** [http://enzyme.expasy.org/EC/1.21.99.4 EC-1.21.99.4]
 
* Synonym(s):
 
* Synonym(s):
** apo-[methylmalonyl-CoA-carboxyltransferase]
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[6.3.4.9-RXN]]
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* With identifiers:
== Reaction(s) known to produce the compound ==
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** 1 [[L-THYROXINE]][c] '''+''' 1 [[Donor-H2]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[Acceptor]][c] '''+''' 1 [[LIOTHYRONINE]][c] '''+''' 1 [[CPD-387]][c]
== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 L-thyroxine[c] '''+''' 1 a reduced electron acceptor[c] '''=>''' 1 H+[c] '''+''' 1 an oxidized electron acceptor[c] '''+''' 1 3,5,3'-triiodo-L-thyronine[c] '''+''' 1 iodide[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* [[Tiso_gene_20481]]
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** IN-SILICO_ANNOTATION
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***EC-NUMBER
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== Pathways  ==
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* [[PWY-6261]], thyroid hormone metabolism II (via conjugation and/or degradation): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6261 PWY-6261]
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** '''11''' reactions found over '''15''' reactions in the full pathway
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* [[PWY-6260]], thyroid hormone metabolism I (via deiodination): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6260 PWY-6260]
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** '''3''' reactions found over '''12''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
{{#set: common name=an apo-[methylmalonyl-CoA:pyruvate carboxytransferase]}}
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* RHEA:
{{#set: common name=apo-[methylmalonyl-CoA-carboxyltransferase]}}
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19745 19745]
{{#set: consumed by=6.3.4.9-RXN}}
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* LIGAND-RXN:
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** [http://www.genome.jp/dbget-bin/www_bget?R03734 R03734]
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* UNIPROT:
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** [http://www.uniprot.org/uniprot/P21195 P21195]
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** [http://www.uniprot.org/uniprot/P49897 P49897]
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** [http://www.uniprot.org/uniprot/P49898 P49898]
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** [http://www.uniprot.org/uniprot/P05307 P05307]
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** [http://www.uniprot.org/uniprot/P09102 P09102]
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** [http://www.uniprot.org/uniprot/P07237 P07237]
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** [http://www.uniprot.org/uniprot/Q922C8 Q922C8]
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** [http://www.uniprot.org/uniprot/P04785 P04785]
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** [http://www.uniprot.org/uniprot/P24389 P24389]
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{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: common name=type_i_iodothyronine_deiodinase}}
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{{#set: ec number=EC-1.21.99.4}}
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{{#set: gene associated=Tiso_gene_20481}}
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{{#set: in pathway=PWY-6261|PWY-6260}}
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{{#set: reconstruction category=annotation}}
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{{#set: reconstruction source=annotation-in-silico_annotation}}
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{{#set: reconstruction tool=pathwaytools}}

Revision as of 00:18, 19 March 2018

Reaction THYROXINE-DEIODINASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • type_i_iodothyronine_deiodinase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 L-thyroxine[c] + 1 a reduced electron acceptor[c] => 1 H+[c] + 1 an oxidized electron acceptor[c] + 1 3,5,3'-triiodo-L-thyronine[c] + 1 iodide[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6261, thyroid hormone metabolism II (via conjugation and/or degradation): PWY-6261
    • 11 reactions found over 15 reactions in the full pathway
  • PWY-6260, thyroid hormone metabolism I (via deiodination): PWY-6260
    • 3 reactions found over 12 reactions in the full pathway

Reconstruction information

External links