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| − | [[Category:Reaction]] | + | [[Category:Metabolite]] |
| − | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLVALERATE-RXN METHYLVALERATE-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=2-Hydroxy-Fatty-Acids 2-Hydroxy-Fatty-Acids] == |
| − | * direction:
| + | |
| − | ** REVERSIBLE
| + | |
| | * common name: | | * common name: |
| − | ** 3-methyl-2-oxobutanoate dehydrogenase [(S)-2-methylbutanoyl-transferring) | + | ** a (2R)-2-hydroxy fatty acid |
| − | ** 2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial
| + | |
| − | * ec number:
| + | |
| − | ** [http://enzyme.expasy.org/EC/1.2.4.4 EC-1.2.4.4]
| + | |
| | * Synonym(s): | | * Synonym(s): |
| | + | ** 2-OH fatty acid |
| | + | ** alpha-Hydroxy fatty acid |
| | + | ** α-OH fatty acid |
| | + | ** α-hydroxy fatty acid |
| | | | |
| − | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
| − | * With identifiers:
| + | == Reaction(s) known to produce the compound == |
| − | ** 1 [[BCAA-dehydrogenase-lipoyl]][c] '''+''' 1 [[2-KETO-3-METHYL-VALERATE]][c] '''+''' 1 [[PROTON]][c] '''<=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[BCAA-dehydrogenase-2MB-DH-lipoyl]][c]
| + | == Reaction(s) of unknown directionality == |
| − | * With common name(s):
| + | * [[CERAMIDASE-YEAST-RXN]] |
| − | ** 1 an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''+''' 1 (S)-3-methyl-2-oxopentanoate[c] '''+''' 1 H+[c] '''<=>''' 1 CO2[c] '''+''' 1 an [apo BCAA dehydrogenase E2 protein] N6-S-[2-methylbutanoyl]dihydrolipoyl-L-lysine[c]
| + | |
| − | | + | |
| − | == Genes associated with this reaction == | + | |
| − | Genes have been associated with this reaction based on different elements listed below.
| + | |
| − | * [[Tiso_gene_18084]]
| + | |
| − | ** [[pantograph]]-[[esiliculosus]]
| + | |
| − | * [[Tiso_gene_3260]]
| + | |
| − | ** IN-SILICO_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | ** EXPERIMENTAL_ANNOTATION
| + | |
| − | ***EC-NUMBER
| + | |
| − | == Pathways == | + | |
| − | == Reconstruction information == | + | |
| − | * Category: [[orthology]] | + | |
| − | ** Source: [[orthology-esiliculosus]]
| + | |
| − | *** Tool: [[pantograph]]
| + | |
| − | * Category: [[annotation]]
| + | |
| − | ** Source: [[annotation-in-silico_annotation]]
| + | |
| − | *** Tool: [[pathwaytools]]
| + | |
| − | ** Source: [[annotation-experimental_annotation]]
| + | |
| − | *** Tool: [[pathwaytools]]
| + | |
| | == External links == | | == External links == |
| − | * UNIPROT:
| + | {{#set: common name=a (2R)-2-hydroxy fatty acid}} |
| − | ** [http://www.uniprot.org/uniprot/P21839 P21839]
| + | {{#set: common name=2-OH fatty acid|alpha-Hydroxy fatty acid|α-OH fatty acid|α-hydroxy fatty acid}} |
| − | ** [http://www.uniprot.org/uniprot/P21953 P21953]
| + | {{#set: reversible reaction associated=CERAMIDASE-YEAST-RXN}} |
| − | ** [http://www.uniprot.org/uniprot/P37940 P37940]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9PK54 Q9PK54]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P37941 P37941]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P11178 P11178]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P12694 P12694]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P09061 P09061]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P09060 P09060]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P11960 P11960]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O84344 O84344]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9Z9E8 Q9Z9E8]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q9I1M2 Q9I1M2]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P35738 P35738]
| + | |
| − | ** [http://www.uniprot.org/uniprot/P50136 P50136]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O48615 O48615]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O03849 O03849]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q53592 Q53592]
| + | |
| − | ** [http://www.uniprot.org/uniprot/Q53593 Q53593]
| + | |
| − | ** [http://www.uniprot.org/uniprot/O82450 O82450]
| + | |
| − | {{#set: direction=REVERSIBLE}}
| + | |
| − | {{#set: common name=3-methyl-2-oxobutanoate dehydrogenase [(S)-2-methylbutanoyl-transferring)}} | + | |
| − | {{#set: common name=2-oxoisovalerate_dehydrogenase_alpha_subunit_mitochondrial}} | + | |
| − | {{#set: ec number=EC-1.2.4.4}}
| + | |
| − | {{#set: gene associated=Tiso_gene_18084|Tiso_gene_3260}}
| + | |
| − | {{#set: in pathway=}}
| + | |
| − | {{#set: reconstruction category=orthology|annotation}}
| + | |
| − | {{#set: reconstruction source=annotation-in-silico_annotation|annotation-experimental_annotation|orthology-esiliculosus}}
| + | |
| − | {{#set: reconstruction tool=pantograph|pathwaytools}} | + | |
