Difference between revisions of "RXN-13294"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYROXINE-DEIODINASE-RXN THYROXINE-DEIODINASE-RXN] == * direction: ** LEFT-TO-RIGHT * common name:...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.4.1.83-RXN 2.4.1.83-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** dolichol_phosphate_ma...")
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=THYROXINE-DEIODINASE-RXN THYROXINE-DEIODINASE-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.4.1.83-RXN 2.4.1.83-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** type_i_iodothyronine_deiodinase
+
** dolichol_phosphate_mannose
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/1.21.99.4 EC-1.21.99.4]
+
** [http://enzyme.expasy.org/EC/2.4.1.83 EC-2.4.1.83]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[L-THYROXINE]][c] '''+''' 1 [[Donor-H2]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[Acceptor]][c] '''+''' 1 [[LIOTHYRONINE]][c] '''+''' 1 [[CPD-387]][c]
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** 1 [[GDP-MANNOSE]][c] '''+''' 1 [[DOLICHOLP]][c] '''=>''' 1 [[GDP]][c] '''+''' 1 [[CPD-171]][c]
 
* With common name(s):
 
* With common name(s):
** 1 L-thyroxine[c] '''+''' 1 a reduced electron acceptor[c] '''=>''' 1 H+[c] '''+''' 1 an oxidized electron acceptor[c] '''+''' 1 3,5,3'-triiodo-L-thyronine[c] '''+''' 1 iodide[c]
+
** 1 GDP-α-D-mannose[c] '''+''' 1 a dolichyl phosphate[c] '''=>''' 1 GDP[c] '''+''' 1 a dolichyl β-D-mannosyl phosphate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[Tiso_gene_20481]]
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* Gene: [[Tiso_gene_16772]]
** IN-SILICO_ANNOTATION
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** Source: [[annotation-in-silico_annotation]]
***EC-NUMBER
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*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-6261]], thyroid hormone metabolism II (via conjugation and/or degradation): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6261 PWY-6261]
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* [[MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS]], protein N-glycosylation (eukaryotic, high mannose): [http://metacyc.org/META/NEW-IMAGE?object=MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS]
** '''11''' reactions found over '''15''' reactions in the full pathway
+
** '''19''' reactions found over '''19''' reactions in the full pathway
* [[PWY-6260]], thyroid hormone metabolism I (via deiodination): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6260 PWY-6260]
+
** '''3''' reactions found over '''12''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
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== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19745 19745]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21184 21184]
 
* LIGAND-RXN:
 
* LIGAND-RXN:
** [http://www.genome.jp/dbget-bin/www_bget?R03734 R03734]
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** [http://www.genome.jp/dbget-bin/www_bget?R01009 R01009]
 
* UNIPROT:
 
* UNIPROT:
** [http://www.uniprot.org/uniprot/P21195 P21195]
+
** [http://www.uniprot.org/uniprot/P14020 P14020]
** [http://www.uniprot.org/uniprot/P49897 P49897]
+
** [http://www.uniprot.org/uniprot/Q26732 Q26732]
** [http://www.uniprot.org/uniprot/P49898 P49898]
+
** [http://www.uniprot.org/uniprot/P54856 P54856]
** [http://www.uniprot.org/uniprot/P05307 P05307]
+
** [http://www.uniprot.org/uniprot/Q9TYJ7 Q9TYJ7]
** [http://www.uniprot.org/uniprot/P09102 P09102]
+
** [http://www.uniprot.org/uniprot/O14466 O14466]
** [http://www.uniprot.org/uniprot/P07237 P07237]
+
** [http://www.uniprot.org/uniprot/Q922C8 Q922C8]
+
** [http://www.uniprot.org/uniprot/P04785 P04785]
+
** [http://www.uniprot.org/uniprot/P24389 P24389]
+
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=type_i_iodothyronine_deiodinase}}
+
{{#set: common name=dolichol_phosphate_mannose}}
{{#set: ec number=EC-1.21.99.4}}
+
{{#set: ec number=EC-2.4.1.83}}
{{#set: gene associated=Tiso_gene_20481}}
+
{{#set: gene associated=Tiso_gene_16772}}
{{#set: in pathway=PWY-6261|PWY-6260}}
+
{{#set: in pathway=MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS}}
{{#set: reconstruction category=annotation}}
+
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction source=annotation-in-silico_annotation}}
+
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}

Revision as of 16:09, 21 March 2018

Reaction 2.4.1.83-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • dolichol_phosphate_mannose
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 GDP-α-D-mannose[c] + 1 a dolichyl phosphate[c] => 1 GDP[c] + 1 a dolichyl β-D-mannosyl phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

Reconstruction information

External links