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| Line 1: |
Line 1: |
| | [[Category:Metabolite]] | | [[Category:Metabolite]] |
| − | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PPI PPI] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CGMP CGMP] == |
| | * smiles: | | * smiles: |
| − | ** O=P(O)(OP([O-])([O-])=O)[O-] | + | ** C4(C3(C(C(C(N2(C1(=C(C(NC(=N1)N)=O)N=C2)))O3)O)OP(O4)(=O)[O-])) |
| | * inchi key: | | * inchi key: |
| − | ** InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K | + | ** InChIKey=ZOOGRGPOEVQQDX-UUOKFMHZSA-M |
| | * common name: | | * common name: |
| − | ** diphosphate | + | ** cyclic-GMP |
| | * molecular weight: | | * molecular weight: |
| − | ** 174.951 | + | ** 344.2 |
| | * Synonym(s): | | * Synonym(s): |
| − | ** PPi | + | ** 3',5'-cyclic GMP |
| − | ** PP | + | ** guanosine-cyclic-phosphoric-acid |
| − | ** pyrophosphate | + | ** cGMP |
| | + | ** guanosine cyclic-monophosphate |
| | + | ** guanosine 3',5'-cyclic-monophosphate |
| | + | ** guanosine 3',5'-cyclic phosphate |
| | + | ** cyclic 3',5'-guanosine monophosphate |
| | | | |
| | == Reaction(s) known to consume the compound == | | == Reaction(s) known to consume the compound == |
| − | * [[INORGPYROPHOSPHAT-RXN]] | + | * [[35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN]] |
| | == Reaction(s) known to produce the compound == | | == Reaction(s) known to produce the compound == |
| − | * [[ARGININE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN66-483]]
| |
| − | * [[RXN66-480]]
| |
| − | * [[RXN-7663]]
| |
| − | * [[RXN0-1602]]
| |
| − | * [[RXN66-484]]
| |
| − | * [[RXN0-2023]]
| |
| − | * [[GMP-SYN-GLUT-RXN]]
| |
| − | * [[RXN66-555]]
| |
| − | * [[RXN0-7248]]
| |
| − | * [[R06284]]
| |
| − | * [[ACYLCOASYN-RXN]]
| |
| − | * [[ACETATE--COA-LIGASE-RXN]]
| |
| − | * [[DIPHTINE--AMMONIA-LIGASE-RXN]]
| |
| − | * [[DCTP-PYROPHOSPHATASE-RXN]]
| |
| − | * [[ASPARTATE--TRNA-LIGASE-RXN]]
| |
| − | * [[2.5.1.32-RXN]]
| |
| − | * [[RXN-12646]]
| |
| − | * [[R223-RXN]]
| |
| − | * [[RXN-11486]]
| |
| − | * [[HISTPRATPHYD-RXN]]
| |
| − | * [[URACIL-PRIBOSYLTRANS-RXN]]
| |
| − | * [[URITRANS-RXN]]
| |
| − | * [[RXN0-1141]]
| |
| − | * [[TRYPTOPHAN--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN-7904]]
| |
| − | * [[RXN-16418]]
| |
| − | * [[TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN]]
| |
| − | * [[RXN-7674]]
| |
| − | * [[6.1.1.24-RXN]]
| |
| − | * [[RXN0-383]]
| |
| − | * [[RXN0-384]]
| |
| − | * [[ASNSYNA-RXN]]
| |
| − | * [[DNA-LIGASE-ATP-RXN]]
| |
| − | * [[LYSINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN0-6274]]
| |
| − | * [[UBIQUITIN--PROTEIN-LIGASE-RXN]]
| |
| − | * [[NUCLEOTIDE-PYROPHOSPHATASE-RXN]]
| |
| − | * [[RXN-12611]]
| |
| − | * [[PANTEPADENYLYLTRAN-RXN]]
| |
| − | * [[RXN-14139]]
| |
| − | * [[RXN-9386]]
| |
| − | * [[RXN-9623]]
| |
| − | * [[2.5.1.39-RXN]]
| |
| − | * [[4-COUMARATE--COA-LIGASE-RXN]]
| |
| − | * [[RXN-8654]]
| |
| − | * [[ASPARAGINE--TRNA-LIGASE-RXN]]
| |
| − | * [[GLUTAMINE--TRNA-LIGASE-RXN]]
| |
| − | * [[GPPS]]
| |
| − | * [[GLCUR1PUT]]
| |
| − | * [[6.3.4.10-RXN]]
| |
| − | * [[ARGSUCCINSYN-RXN]]
| |
| − | * [[RXN-2001]]
| |
| − | * [[2.7.7.13-RXN]]
| |
| − | * [[DGTD]]
| |
| − | * [[THREONINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN-17917]]
| |
| − | * [[GGPS]]
| |
| − | * [[METHIONINE--TRNA-LIGASE-RXN]]
| |
| − | * [[6.2.1.34-RXN]]
| |
| − | * [[XANPRIBOSYLTRAN-RXN]]
| |
| − | * [[RXN-12978]]
| |
| − | * [[NICONUCADENYLYLTRAN-RXN]]
| |
| − | * [[RXN-10919]]
| |
| − | * [[RXN-4305]]
| |
| − | * [[FADSYN-RXN]]
| |
| − | * [[ALANINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN-14140]]
| |
| − | * [[RME256]]
| |
| − | * [[RME255]]
| |
| − | * [[RXN0-5107]]
| |
| − | * [[DNA-DIRECTED-DNA-POLYMERASE-RXN]]
| |
| − | * [[RXN0-7239]]
| |
| − | * [[UTPPH]]
| |
| − | * [[RXN0-2161]]
| |
| − | * [[4OHBENZOATE-OCTAPRENYLTRANSFER-RXN]]
| |
| − | * [[RXN-9644]]
| |
| − | * [[GSADENYLATION-RXN]]
| |
| − | * [[RXN0-7238]]
| |
| − | * [[RXN-12720]]
| |
| − | * [[ADENYLATECYC-RXN]]
| |
| − | * [[PROLINE--TRNA-LIGASE-RXN]]
| |
| − | * [[NTPD]]
| |
| − | * [[2.7.7.14-RXN]]
| |
| − | * [[QUINOPRIBOTRANS-RXN]]
| |
| − | * [[VALINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN-1126]]
| |
| − | * [[S-ADENMETSYN-RXN]]
| |
| − | * [[RXN-16165]]
| |
| − | * [[UG1PUT]]
| |
| − | * [[H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN]]
| |
| − | * [[FPPSYN-RXN]]
| |
| − | * [[THI-P-SYN-RXN]]
| |
| − | * [[DUTNH]]
| |
| − | * [[FARNESYLTRANSTRANSFERASE-RXN]]
| |
| − | * [[P-PANTOCYSLIG-RXN]]
| |
| − | * [[RXN66-477]]
| |
| − | * [[HISTIDINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN66-474]]
| |
| − | * [[RXN-12184]]
| |
| − | * [[RXN-13290]]
| |
| − | * [[RNA-LIGASE-ATP-RXN]]
| |
| − | * [[TYROSINE--TRNA-LIGASE-RXN]]
| |
| − | * [[MRNA-GUANYLYLTRANSFERASE-RXN]]
| |
| − | * [[RXN-16393]]
| |
| − | * [[RXN-16389]]
| |
| − | * [[ASNSYNB-RXN]]
| |
| − | * [[GTP-CYCLOHYDRO-II-RXN]]
| |
| − | * [[TRANS-RXN0-623]]
| |
| − | * [[RXN-12610]]
| |
| − | * [[R06858]]
| |
| − | * [[2.4.2.12-RXN]]
| |
| − | * [[H2PTEROATESYNTH-RXN]]
| |
| − | * [[RXN0-1603]]
| |
| − | * [[RXN66-474-R-2-HYDROXYSTEARATE/ATP/CO-A//CPD-14717/AMP/PPI.48.]]
| |
| − | * [[RXN0-5515]]
| |
| − | * [[RXN-8999]]
| |
| − | * [[GMP-SYN-NH3-RXN]]
| |
| − | * [[NAG1P-URIDYLTRANS-RXN]]
| |
| − | * [[RXNARA-8002]]
| |
| − | * [[RXN-16401]]
| |
| − | * [[RXN-16402]]
| |
| − | * [[RXN66-469]]
| |
| − | * [[GAMPG]]
| |
| − | * [[SERINE--TRNA-LIGASE-RXN]]
| |
| − | * [[LINOLENOYL-RXN]]
| |
| − | * [[RXN0-6427]]
| |
| − | * [[PANTOATE-BETA-ALANINE-LIG-RXN]]
| |
| − | * [[2.7.7.60-RXN]]
| |
| − | * [[RXN0-7192]]
| |
| − | * [[RXN-16380]]
| |
| − | * [[RNA-3-PHOSPHATE-CYCLASE-RXN]]
| |
| − | * [[RXN-9673]]
| |
| − | * [[NTDP]]
| |
| − | * [[CYSTEINE--TRNA-LIGASE-RXN]]
| |
| − | * [[6.3.4.11-RXN]]
| |
| − | * [[LEUCINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN-13614]]
| |
| − | * [[GLYCINE--TRNA-LIGASE-RXN]]
| |
| − | * [[PHENYLALANINE--TRNA-LIGASE-RXN]]
| |
| − | * [[ADEC]]
| |
| − | * [[CDPDIGLYSYN-RXN]]
| |
| − | * [[LNLNCACOAL]]
| |
| − | * [[RXN-10]]
| |
| − | * [[HYPOXANPRIBOSYLTRAN-RXN]]
| |
| − | * [[RXN-10695]]
| |
| − | * [[RXN0-5098]]
| |
| − | * [[PRADP]]
| |
| − | * [[ISOLEUCINE--TRNA-LIGASE-RXN]]
| |
| − | * [[RXN-2541]]
| |
| − | * [[RXN-4303]]
| |
| − | * [[6.3.4.9-RXN]]
| |
| − | * [[BIOTINLIG-RXN]]
| |
| − | * [[PPGPPSYN-RXN]]
| |
| − | * [[RXN-17127]]
| |
| − | * [[LNLCCOAL]]
| |
| − | * [[RXN-12245]]
| |
| − | * [[RXN-9003]]
| |
| − | * [[ITPP]]
| |
| − | * [[RXN-17925]]
| |
| − | * [[GLURS-RXN]]
| |
| − | * [[RXN0-6382]]
| |
| − | * [[FACOAL18111Z]]
| |
| − | * [[DUTP-PYROP-RXN]]
| |
| − | * [[RXN0-385]]
| |
| | == Reaction(s) of unknown directionality == | | == Reaction(s) of unknown directionality == |
| − | * [[RXN1F-144]]
| |
| | * [[GUANYLCYC-RXN]] | | * [[GUANYLCYC-RXN]] |
| − | * [[RNA-DIRECTED-DNA-POLYMERASE-RXN]]
| |
| − | * [[ATPPHOSPHORIBOSYLTRANS-RXN]]
| |
| − | * [[RXN-3701]]
| |
| − | * [[GBDP]]
| |
| − | * [[RXN1F-66]]
| |
| − | * [[2.7.7.11-RXN]]
| |
| − | * [[2.5.1.58-RXN]]
| |
| − | * [[TCM3]]
| |
| − | * [[RXN-13323]]
| |
| − | * [[OROPRIBTRANS-RXN]]
| |
| − | * [[TCP26]]
| |
| − | * [[SULFATE-ADENYLYLTRANS-RXN]]
| |
| − | * [[RXN0-5180]]
| |
| − | * [[RXN-16415]]
| |
| − | * [[RXN-7673]]
| |
| − | * [[PRTRANS-RXN]]
| |
| − | * [[PRPPAMIDOTRANS-RXN]]
| |
| − | * [[UTPHEXPURIDYLYLTRANS-RXN]]
| |
| − | * [[DNA-DIRECTED-RNA-POLYMERASE-RXN]]
| |
| − | * [[DTDPGLUCOSEPP-RXN]]
| |
| − | * [[GUANPRIBOSYLTRAN-RXN]]
| |
| − | * [[GLUC1PURIDYLTRANS-RXN]]
| |
| − | * [[orPRT]]
| |
| − | * [[TCX10]]
| |
| − | * [[2.7.1.90-RXN]]
| |
| − | * [[GPPSYN-RXN]]
| |
| − | * [[POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN]]
| |
| − | * [[2.7.7.44-RXN]]
| |
| | == External links == | | == External links == |
| − | * CAS : 2466-09-3 | + | * CAS : 7665-99-8 |
| − | * METABOLIGHTS : MTBLC33019
| + | |
| − | * DRUGBANK : DB04160
| + | |
| | * PUBCHEM: | | * PUBCHEM: |
| − | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1023 1023] | + | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=16727415 16727415] |
| − | * HMDB : HMDB00250 | + | * HMDB : HMDB01314 |
| | * LIGAND-CPD: | | * LIGAND-CPD: |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?C00013 C00013] | + | ** [http://www.genome.jp/dbget-bin/www_bget?C00942 C00942] |
| | * CHEMSPIDER: | | * CHEMSPIDER: |
| − | ** [http://www.chemspider.com/Chemical-Structure.996.html 996] | + | ** [http://www.chemspider.com/Chemical-Structure.20559156.html 20559156] |
| | * CHEBI: | | * CHEBI: |
| − | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=29888 29888] | + | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57746 57746] |
| − | * BIGG : ppi | + | * METABOLIGHTS : MTBLC57746 |
| − | {{#set: smiles=O=P(O)(OP([O-])([O-])=O)[O-]}} | + | {{#set: smiles=C4(C3(C(C(C(N2(C1(=C(C(NC(=N1)N)=O)N=C2)))O3)O)OP(O4)(=O)[O-]))}} |
| − | {{#set: inchi key=InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K}} | + | {{#set: inchi key=InChIKey=ZOOGRGPOEVQQDX-UUOKFMHZSA-M}} |
| − | {{#set: common name=diphosphate}} | + | {{#set: common name=cyclic-GMP}} |
| − | {{#set: molecular weight=174.951 }} | + | {{#set: molecular weight=344.2 }} |
| − | {{#set: common name=PPi|PP|pyrophosphate}} | + | {{#set: common name=3',5'-cyclic GMP|guanosine-cyclic-phosphoric-acid|cGMP|guanosine cyclic-monophosphate|guanosine 3',5'-cyclic-monophosphate|guanosine 3',5'-cyclic phosphate|cyclic 3',5'-guanosine monophosphate}} |
| − | {{#set: consumed by=INORGPYROPHOSPHAT-RXN}}
| + | {{#set: consumed by=35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN}} |
| − | {{#set: produced by=ARGININE--TRNA-LIGASE-RXN|RXN66-483|RXN66-480|RXN-7663|RXN0-1602|RXN66-484|RXN0-2023|GMP-SYN-GLUT-RXN|RXN66-555|RXN0-7248|R06284|ACYLCOASYN-RXN|ACETATE--COA-LIGASE-RXN|DIPHTINE--AMMONIA-LIGASE-RXN|DCTP-PYROPHOSPHATASE-RXN|ASPARTATE--TRNA-LIGASE-RXN|2.5.1.32-RXN|RXN-12646|R223-RXN|RXN-11486|HISTPRATPHYD-RXN|URACIL-PRIBOSYLTRANS-RXN|URITRANS-RXN|RXN0-1141|TRYPTOPHAN--TRNA-LIGASE-RXN|RXN-7904|RXN-16418|TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN|RXN-7674|6.1.1.24-RXN|RXN0-383|RXN0-384|ASNSYNA-RXN|DNA-LIGASE-ATP-RXN|LYSINE--TRNA-LIGASE-RXN|RXN0-6274|UBIQUITIN--PROTEIN-LIGASE-RXN|NUCLEOTIDE-PYROPHOSPHATASE-RXN|RXN-12611|PANTEPADENYLYLTRAN-RXN|RXN-14139|RXN-9386|RXN-9623|2.5.1.39-RXN|4-COUMARATE--COA-LIGASE-RXN|RXN-8654|ASPARAGINE--TRNA-LIGASE-RXN|GLUTAMINE--TRNA-LIGASE-RXN|GPPS|GLCUR1PUT|6.3.4.10-RXN|ARGSUCCINSYN-RXN|RXN-2001|2.7.7.13-RXN|DGTD|THREONINE--TRNA-LIGASE-RXN|RXN-17917|GGPS|METHIONINE--TRNA-LIGASE-RXN|6.2.1.34-RXN|XANPRIBOSYLTRAN-RXN|RXN-12978|NICONUCADENYLYLTRAN-RXN|RXN-10919|RXN-4305|FADSYN-RXN|ALANINE--TRNA-LIGASE-RXN|RXN-14140|RME256|RME255|RXN0-5107|DNA-DIRECTED-DNA-POLYMERASE-RXN|RXN0-7239|UTPPH|RXN0-2161|4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|RXN-9644|GSADENYLATION-RXN|RXN0-7238|RXN-12720|ADENYLATECYC-RXN|PROLINE--TRNA-LIGASE-RXN|NTPD|2.7.7.14-RXN|QUINOPRIBOTRANS-RXN|VALINE--TRNA-LIGASE-RXN|RXN-1126|S-ADENMETSYN-RXN|RXN-16165|UG1PUT|H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN|FPPSYN-RXN|THI-P-SYN-RXN|DUTNH|FARNESYLTRANSTRANSFERASE-RXN|P-PANTOCYSLIG-RXN|RXN66-477|HISTIDINE--TRNA-LIGASE-RXN|RXN66-474|RXN-12184|RXN-13290|RNA-LIGASE-ATP-RXN|TYROSINE--TRNA-LIGASE-RXN|MRNA-GUANYLYLTRANSFERASE-RXN|RXN-16393|RXN-16389|ASNSYNB-RXN|GTP-CYCLOHYDRO-II-RXN|TRANS-RXN0-623|RXN-12610|R06858|2.4.2.12-RXN|H2PTEROATESYNTH-RXN|RXN0-1603|RXN66-474-R-2-HYDROXYSTEARATE/ATP/CO-A//CPD-14717/AMP/PPI.48.|RXN0-5515|RXN-8999|GMP-SYN-NH3-RXN|NAG1P-URIDYLTRANS-RXN|RXNARA-8002|RXN-16401|RXN-16402|RXN66-469|GAMPG|SERINE--TRNA-LIGASE-RXN|LINOLENOYL-RXN|RXN0-6427|PANTOATE-BETA-ALANINE-LIG-RXN|2.7.7.60-RXN|RXN0-7192|RXN-16380|RNA-3-PHOSPHATE-CYCLASE-RXN|RXN-9673|NTDP|CYSTEINE--TRNA-LIGASE-RXN|6.3.4.11-RXN|LEUCINE--TRNA-LIGASE-RXN|RXN-13614|GLYCINE--TRNA-LIGASE-RXN|PHENYLALANINE--TRNA-LIGASE-RXN|ADEC|CDPDIGLYSYN-RXN|LNLNCACOAL|RXN-10|HYPOXANPRIBOSYLTRAN-RXN|RXN-10695|RXN0-5098|PRADP|ISOLEUCINE--TRNA-LIGASE-RXN|RXN-2541|RXN-4303|6.3.4.9-RXN|BIOTINLIG-RXN|PPGPPSYN-RXN|RXN-17127|LNLCCOAL|RXN-12245|RXN-9003|ITPP|RXN-17925|GLURS-RXN|RXN0-6382|FACOAL18111Z|DUTP-PYROP-RXN|RXN0-385}}
| + | {{#set: consumed or produced by=GUANYLCYC-RXN}} |
| − | {{#set: consumed or produced by=RXN1F-144|GUANYLCYC-RXN|RNA-DIRECTED-DNA-POLYMERASE-RXN|ATPPHOSPHORIBOSYLTRANS-RXN|RXN-3701|GBDP|RXN1F-66|2.7.7.11-RXN|2.5.1.58-RXN|TCM3|RXN-13323|OROPRIBTRANS-RXN|TCP26|SULFATE-ADENYLYLTRANS-RXN|RXN0-5180|RXN-16415|RXN-7673|PRTRANS-RXN|PRPPAMIDOTRANS-RXN|UTPHEXPURIDYLYLTRANS-RXN|DNA-DIRECTED-RNA-POLYMERASE-RXN|DTDPGLUCOSEPP-RXN|GUANPRIBOSYLTRAN-RXN|GLUC1PURIDYLTRANS-RXN|orPRT|TCX10|2.7.1.90-RXN|GPPSYN-RXN|POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN|2.7.7.44-RXN}} | + | |
