Difference between revisions of "GLUTATHIONE-REDUCT-NADPH-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-15684 RXN-15684] == * direction: ** LEFT-TO-RIGHT * common name: ** FAD-dependent 3-benzyl-3,6...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTATHIONE-REDUCT-NADPH-RXN GLUTATHIONE-REDUCT-NADPH-RXN] == * direction: ** LEFT-TO-RIGHT * commo...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-15684 RXN-15684] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTATHIONE-REDUCT-NADPH-RXN GLUTATHIONE-REDUCT-NADPH-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** FAD-dependent 3-benzyl-3,6 -dithio-6-(hydroxymethyl)-diketopiperazine dithiol oxidase
+
** glutathione_reductase
−
** sulfhydryl_oxidase
+
−
** sulfhydryl_oxidase_1
+
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.8.3.2 EC-1.8.3.2]
+
** [http://enzyme.expasy.org/EC/1.8.1.7 EC-1.8.1.7]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[CPD-17049]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''=>''' 1 [[HYDROGEN-PEROXIDE]][c] '''+''' 1 [[CPD-17050]][c]
+
** 1 [[PROTON]][c] '''+''' 1 [[OXIDIZED-GLUTATHIONE]][c] '''+''' 1 [[NADPH]][c] '''=>''' 2 [[GLUTATHIONE]][c] '''+''' 1 [[NADP]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 3-benzyl-3,6 -dithio-6-(hydroxymethyl)-diketopiperazine[c] '''+''' 1 oxygen[c] '''=>''' 1 hydrogen peroxide[c] '''+''' 1 3-benzyl-3,6 -disulfide-6-(hydroxymethyl)-diketopiperazine[c]
+
** 1 H+[c] '''+''' 1 glutathione disulfide[c] '''+''' 1 NADPH[c] '''=>''' 2 glutathione[c] '''+''' 1 NADP+[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* Gene: [[Tiso_gene_13846]]
+
* Gene: [[Tiso_gene_2804]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
* Gene: [[Tiso_gene_17069]]
+
** Source: [[annotation-experimental_annotation]]
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_16192]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_20164]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_7321]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_9472]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_20163]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_12069]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
** Source: [[orthology-esiliculosus]]
+
** Source: [[orthology-athaliana]]
−
* Gene: [[Tiso_gene_8416]]
+
* Gene: [[Tiso_gene_12533]]
−
** Source: [[annotation-in-silico_annotation]]
+
−
*** Assignment: AUTOMATED-NAME-MATCH
+
−
* Gene: [[Tiso_gene_3314]]
+
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
−
** Source: [[orthology-esiliculosus]]
+
** Source: [[annotation-experimental_annotation]]
−
* Gene: [[Tiso_gene_13847]]
+
−
** Source: [[annotation-in-silico_annotation]]
+
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-athaliana]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
−
* Gene: [[Tiso_gene_4530]]
 
−
** Source: [[annotation-in-silico_annotation]]
 
−
*** Assignment: AUTOMATED-NAME-MATCH
 
−
* Gene: [[Tiso_gene_12454]]
 
−
** Source: [[annotation-in-silico_annotation]]
 
−
*** Assignment: AUTOMATED-NAME-MATCH
 
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-7533]], gliotoxin biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7533 PWY-7533]
+
* [[GLUT-REDOX-PWY]], glutathione-glutaredoxin redox reactions: [http://metacyc.org/META/NEW-IMAGE?object=GLUT-REDOX-PWY GLUT-REDOX-PWY]
−
** '''2''' reactions found over '''9''' reactions in the full pathway
+
** '''2''' reactions found over '''2''' reactions in the full pathway
 +
* [[PWY-4081]], glutathione-peroxide redox reactions: [http://metacyc.org/META/NEW-IMAGE?object=PWY-4081 PWY-4081]
 +
** '''3''' reactions found over '''3''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
 +
** Source: [[orthology-athaliana]]
 +
*** Tool: [[pantograph]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
 +
* Category: [[manual]]
 +
** Source: [[manual-primary_network]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-experimental_annotation]]
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* RHEA:
 +
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11740 11740]
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R00115 R00115]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P43783 P43783]
 +
** [http://www.uniprot.org/uniprot/Q9CH92 Q9CH92]
 +
** [http://www.uniprot.org/uniprot/P48639 P48639]
 +
** [http://www.uniprot.org/uniprot/P11804 P11804]
 +
** [http://www.uniprot.org/uniprot/P06715 P06715]
 +
** [http://www.uniprot.org/uniprot/P23189 P23189]
 +
** [http://www.uniprot.org/uniprot/P80461 P80461]
 +
** [http://www.uniprot.org/uniprot/Q60151 Q60151]
 +
** [http://www.uniprot.org/uniprot/P41921 P41921]
 +
** [http://www.uniprot.org/uniprot/Q9TWE1 Q9TWE1]
 +
** [http://www.uniprot.org/uniprot/O64409 O64409]
 +
** [http://www.uniprot.org/uniprot/Q43621 Q43621]
 +
** [http://www.uniprot.org/uniprot/P48640 P48640]
 +
** [http://www.uniprot.org/uniprot/Q43154 Q43154]
 +
** [http://www.uniprot.org/uniprot/Q93379 Q93379]
 +
** [http://www.uniprot.org/uniprot/P78965 P78965]
 +
** [http://www.uniprot.org/uniprot/P42770 P42770]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=FAD-dependent 3-benzyl-3,6 -dithio-6-(hydroxymethyl)-diketopiperazine dithiol oxidase}}
+
{{#set: common name=glutathione_reductase}}
−
{{#set: common name=sulfhydryl_oxidase}}
+
{{#set: ec number=EC-1.8.1.7}}
−
{{#set: common name=sulfhydryl_oxidase_1}}
+
{{#set: gene associated=Tiso_gene_2804|Tiso_gene_12533}}
−
{{#set: ec number=EC-1.8.3.2}}
+
{{#set: in pathway=GLUT-REDOX-PWY|PWY-4081}}
−
{{#set: gene associated=Tiso_gene_13846|Tiso_gene_17069|Tiso_gene_16192|Tiso_gene_20164|Tiso_gene_7321|Tiso_gene_9472|Tiso_gene_20163|Tiso_gene_12069|Tiso_gene_8416|Tiso_gene_3314|Tiso_gene_13847|Tiso_gene_4530|Tiso_gene_12454}}
+
{{#set: reconstruction category=orthology|manual|annotation}}
−
{{#set: in pathway=PWY-7533}}
+
{{#set: reconstruction source=annotation-in-silico_annotation|manual-primary_network|annotation-experimental_annotation|orthology-athaliana|orthology-esiliculosus}}
−
{{#set: reconstruction category=orthology|annotation}}
+
−
{{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}}
+
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 20:18, 21 March 2018

Reaction GLUTATHIONE-REDUCT-NADPH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • glutathione_reductase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • GLUT-REDOX-PWY, glutathione-glutaredoxin redox reactions: GLUT-REDOX-PWY
    • 2 reactions found over 2 reactions in the full pathway
  • PWY-4081, glutathione-peroxide redox reactions: PWY-4081
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links





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