|
|
| Line 1: |
Line 1: |
| − | [[Category:Metabolite]] | + | [[Category:Pathway]] |
| − | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CO-A CO-A] == | + | == Pathway [http://metacyc.org/META/NEW-IMAGE?object=PWY-7382 PWY-7382] == |
| − | * smiles: | + | * taxonomic range: |
| − | ** CC(C)(C(O)C(=O)NCCC(=O)NCCS)COP(=O)(OP(=O)(OCC1(OC(C(C1OP([O-])(=O)[O-])O)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-] | + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-4751 TAX-4751] |
| − | * inchi key:
| + | |
| − | ** InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-J
| + | |
| | * common name: | | * common name: |
| − | ** coenzyme A | + | ** lipoate biosynthesis and incorporation (yeast) |
| − | * molecular weight:
| + | |
| − | ** 763.502
| + | |
| | * Synonym(s): | | * Synonym(s): |
| − | ** CoA
| |
| − | ** co-A-SH
| |
| − | ** co-enzyme-A
| |
| − | ** co-A
| |
| − | ** HS-CoA
| |
| | | | |
| − | == Reaction(s) known to consume the compound == | + | == Reaction(s) found == |
| − | * [[RXN-2006]] | + | * '''4''' reaction(s) found |
| − | * [[RXN66-483]] | + | ** [[RXN-14959]] |
| − | * [[RXN66-480]]
| + | ** [[RXN-14950]] |
| − | * [[RXN-16561]] | + | ** [[RXN-13037]] |
| − | * [[RXN66-469]] | + | ** [[RXN-14957]] |
| − | * [[RXN66-484]]
| + | == Reaction(s) not found == |
| − | * [[RXN-16418]] | + | * '''3''' reaction(s) not found |
| − | * [[RXN-17116]] | + | ** [http://metacyc.org/META/NEW-IMAGE?object=RXN-14958 RXN-14958] |
| − | * [[RXN-1126]] | + | ** [http://metacyc.org/META/NEW-IMAGE?object=RXN-14955 RXN-14955] |
| − | * [[RXN0-7248]] | + | ** [http://metacyc.org/META/NEW-IMAGE?object=RXN-14954 RXN-14954] |
| − | * [[2.3.1.176-RXN]]
| + | |
| − | * [[RXN-14268]] | + | |
| − | * [[RXN-2001]]
| + | |
| − | * [[RXN-16389]]
| + | |
| − | * [[ACYLCOASYN-RXN]]
| + | |
| − | * [[RXN-17791]]
| + | |
| − | * [[RXN3O-5304]]
| + | |
| − | * [[RXN-11921]]
| + | |
| − | * [[RXN-16380]]
| + | |
| − | * [[LNLNCACOAL]]
| + | |
| − | * [[RXN-10919]]
| + | |
| − | * [[RXN-13617]]
| + | |
| − | * [[ACETATE--COA-LIGASE-RXN]]
| + | |
| − | * [[RXN3O-9780]]
| + | |
| − | * [[RXN-10699]]
| + | |
| − | * [[RXN-9673]]
| + | |
| − | * [[BNorh]]
| + | |
| − | * [[RXN-16401]]
| + | |
| − | * [[RXN-8988]]
| + | |
| − | * [[PYRUVDEH-RXN]]
| + | |
| − | * [[RXN-15889]]
| + | |
| − | * [[RXN-17795]]
| + | |
| − | * [[RXN-13614]]
| + | |
| − | * [[DHRT_2mbcoa]]
| + | |
| − | * [[RXN-16137]]
| + | |
| − | * [[2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN]]
| + | |
| − | * [[RXN-12978]]
| + | |
| − | * [[DHRT_ibcoa]]
| + | |
| − | * [[TRANS-RXN0-623]]
| + | |
| − | * [[RXN-17799]]
| + | |
| − | * [[RXN-17778]]
| + | |
| − | * [[RXN-7904]]
| + | |
| − | * [[RXN66-474]]
| + | |
| − | * [[RXN-10695]]
| + | |
| − | * [[RXN-14793]]
| + | |
| − | * [[KETOACYLCOATHIOL-RXN]]
| + | |
| − | * [[2.3.1.155-RXN]]
| + | |
| − | * [[ACCAT]]
| + | |
| − | * [[RXN-13290]]
| + | |
| − | * [[RXN-11213]]
| + | |
| − | * [[RXN66-477]]
| + | |
| − | * [[RXN-14799]]
| + | |
| − | * [[AKBLIG-RXN]]
| + | |
| − | * [[RXN-12184]]
| + | |
| − | * [[RXN-14774]]
| + | |
| − | * [[RXN-17787]]
| + | |
| − | * [[BNor]]
| + | |
| − | * [[LNLCCOAL]]
| + | |
| − | * [[LINOLENOYL-RXN]]
| + | |
| − | * [[RXN0-7239]]
| + | |
| − | * [[RXN-12710]]
| + | |
| − | * [[RXN-14803]]
| + | |
| − | * [[RXN-16393]]
| + | |
| − | * [[HOLO-ACP-SYNTH-RXN]]
| + | |
| − | * [[R223-RXN]]
| + | |
| − | * [[RXN-2902]]
| + | |
| − | * [[RXN-11917]]
| + | |
| − | * [[RXN-17782]]
| + | |
| − | * [[RXN-10700]]
| + | |
| − | * [[RXN-10701]]
| + | |
| − | * [[RXN-9644]]
| + | |
| − | * [[RXN-11246]]
| + | |
| − | * [[1.2.1.27-RXN]]
| + | |
| − | * [[RXN0-7238]]
| + | |
| − | * [[RXN-14394]]
| + | |
| − | * [[RXN66-474-R-2-HYDROXYSTEARATE/ATP/CO-A//CPD-14717/AMP/PPI.48.]]
| + | |
| − | * [[RXN-14788]]
| + | |
| − | * [[6.2.1.34-RXN]]
| + | |
| − | * [[2-KETO-ADIPATE-DEHYDROG-RXN]]
| + | |
| − | * [[RXN-9623]]
| + | |
| − | * [[FACOAL18111Z]]
| + | |
| − | * [[ENTDB-RXN]]
| + | |
| − | * [[4-COUMARATE--COA-LIGASE-RXN]]
| + | |
| − | * [[1.2.1.25-RXN]]
| + | |
| − | * [[RXN-16402]]
| + | |
| − | == Reaction(s) known to produce the compound == | + | |
| − | * [[DEPHOSPHOCOAKIN-RXN]] | + | |
| − | * [[IPMS]]
| + | |
| − | * [[RXN-10821]]
| + | |
| − | * [[3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN]]
| + | |
| − | * [[RXN-12565]]
| + | |
| − | * [[RXN-17729]]
| + | |
| − | * [[FATTY-ACYL-COA-SYNTHASE-RXN]]
| + | |
| − | * [[THIOESTER-RXN]]
| + | |
| − | * [[RXN-16118]]
| + | |
| − | * [[MALSYN-RXN]]
| + | |
| − | * [[RXN-3142]]
| + | |
| − | * [[RXN-15044]]
| + | |
| − | * [[RXN-15045]]
| + | |
| − | * [[RXN-15043]]
| + | |
| − | * [[RXN0-6948]]
| + | |
| − | * [[RXN-17855]]
| + | |
| − | * [[RXN-17854]]
| + | |
| − | * [[RXN-17857]]
| + | |
| − | * [[RXN-17856]]
| + | |
| − | * [[RXN-17851]]
| + | |
| − | * [[RXN-17850]]
| + | |
| − | * [[RXN-17853]]
| + | |
| − | * [[RXN-17852]]
| + | |
| − | * [[RXN-17859]]
| + | |
| − | * [[RXN-17858]]
| + | |
| − | * [[RXN-9629]]
| + | |
| − | * [[FACOAE1839Z12Z15Z]]
| + | |
| − | * [[RXN1G-445]]
| + | |
| − | * [[RXN-16100]]
| + | |
| − | * [[RXN-1106]]
| + | |
| − | * [[RXN3DJ-118]]
| + | |
| − | * [[RXN-1101]]
| + | |
| − | * [[RXN1G-368]]
| + | |
| − | * [[2.3.1.165-RXN]]
| + | |
| − | * [[RXN-12547]]
| + | |
| − | * [[RXN-9627]]
| + | |
| − | * [[RXN-13322]]
| + | |
| − | * [[RXN-9632]]
| + | |
| − | * [[RXN-9624]]
| + | |
| − | * [[2-ISOPROPYLMALATESYN-RXN]]
| + | |
| − | * [[RXN-17021]]
| + | |
| − | * [[RXN-17023]]
| + | |
| − | * [[RXN-7697]]
| + | |
| − | * [[DIHYDLIPACETRANS-RXN]]
| + | |
| − | * [[RXN-15090]]
| + | |
| − | * [[CITSYN-RXN]]
| + | |
| − | * [[CSm]]
| + | |
| − | * [[RXN-9648]]
| + | |
| − | * [[RXN-6384]]
| + | |
| − | * [[RXN-1623]]
| + | |
| − | * [[CSx]]
| + | |
| − | * [[RXN-13721]]
| + | |
| − | * [[RXN-13435]]
| + | |
| − | * [[RXN-13431]]
| + | |
| − | * [[RXN-13430]]
| + | |
| − | * [[RXN-16082]]
| + | |
| − | * [[ACYL-COA-HYDROLASE-RXN]]
| + | |
| − | * [[7KAPSYN-RXN]]
| + | |
| − | * [[2.3.1.118-RXN]]
| + | |
| − | * [[RXN-9652]]
| + | |
| − | * [[RXN-9651]]
| + | |
| − | * [[RXN-9650]]
| + | |
| − | * [[RXN-17864]]
| + | |
| − | * [[RXN-9654]]
| + | |
| − | * [[RXN-17860]]
| + | |
| − | * [[RXN-17861]]
| + | |
| − | * [[RXN-17862]]
| + | |
| − | * [[RXN-17863]]
| + | |
| − | * [[RXN-9543]]
| + | |
| − | * [[RXN-9653]]
| + | |
| − | * [[ISOVALERYLCOA-DHLIPOAMIDE-RXN]]
| + | |
| − | * [[DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN-16094]]
| + | |
| − | * [[RXN-16098]]
| + | |
| − | * [[ACACT7m]]
| + | |
| − | * [[ACDHmi]]
| + | |
| − | * [[ACACT]]
| + | |
| − | * [[RXN-13297]]
| + | |
| − | * [[RXN-13296]]
| + | |
| − | * [[RXN-13295]]
| + | |
| − | * [[RXN-13294]]
| + | |
| − | * [[HICH]]
| + | |
| − | * [[RXN-16017]]
| + | |
| − | * [[RXN1G-499]]
| + | |
| − | * [[RXN-9666]]
| + | |
| − | * [[ARYLAMINE-N-ACETYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN-10708]]
| + | |
| − | * [[RXN0-1133]]
| + | |
| − | * [[LINOLEOYL-RXN]]
| + | |
| − | * [[SERINE-C-PALMITOYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN-17011]]
| + | |
| − | * [[RXN-17010]]
| + | |
| − | * [[RXN-17019]]
| + | |
| − | * [[MALONYL-COA-ACP-TRANSACYL-RXN]]
| + | |
| − | * [[ACDHi]]
| + | |
| − | * [[ADCPT]]
| + | |
| − | * [[2.3.1.180-RXN]]
| + | |
| − | * [[RXN-13446]]
| + | |
| − | * [[RXN-13442]]
| + | |
| − | * [[RXN-13441]]
| + | |
| − | * [[RXN-7743]]
| + | |
| − | * [[RXN-10059]]
| + | |
| − | * [[RXN-17008]]
| + | |
| − | * [[RXN-17009]]
| + | |
| − | * [[RXN-16032]]
| + | |
| − | * [[RXN-12362]]
| + | |
| − | * [[RXN-12363]]
| + | |
| − | * [[RXN-1381]]
| + | |
| − | * [[GLUCOSAMINEPNACETYLTRANS-RXN]]
| + | |
| − | * [[RXN-9192]]
| + | |
| − | * [[SERINE-O-ACETTRAN-RXN]]
| + | |
| − | * [[PALMITOYL-COA-HYDROLASE-RXN]]
| + | |
| − | == Reaction(s) of unknown directionality ==
| + | |
| − | * [[RXN-16759]] | + | |
| − | * [[RXN1G-460]] | + | |
| − | * [[RXN-16063]]
| + | |
| − | * [[RXN-1124]]
| + | |
| − | * [[2.3.1.168-RXN]]
| + | |
| − | * [[RXN-16066]]
| + | |
| − | * [[TUBULIN-N-ACETYLTRANSFERASE-RXN]]
| + | |
| − | * [[ACCOAtx]]
| + | |
| − | * [[RXN-16103]]
| + | |
| − | * [[RXN-10994]] | + | |
| − | * [[RXN-16415]] | + | |
| − | * [[HOMOSERINE-O-ACETYLTRANSFERASE-RXN]]
| + | |
| − | * [[SUCCINATE--COA-LIGASE-GDP-FORMING-RXN]]
| + | |
| − | * [[2.3.1.97-RXN]]
| + | |
| − | * [[1.1.1.34-RXN]]
| + | |
| − | * [[HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN]]
| + | |
| − | * [[RXN-13671]] | + | |
| − | * [[RXN-12561]] | + | |
| − | * [[RXN-15036]]
| + | |
| − | * [[RXN-13871]]
| + | |
| − | * [[2KETO-3METHYLVALERATE-RXN]]
| + | |
| − | * [[HISTONE-ACETYLTRANSFERASE-RXN]]
| + | |
| − | * [[RXN-14274]]
| + | |
| − | * [[RXN-14277]]
| + | |
| − | * [[RXN0-1147]]
| + | |
| − | * [[ACCOAth]]
| + | |
| − | * [[RXN-8032]]
| + | |
| − | * [[ACACT6]]
| + | |
| − | * [[ACACT7]]
| + | |
| − | * [[ACACT4]]
| + | |
| − | * [[ACCOAtm]]
| + | |
| − | * [[2.3.1.23-RXN]]
| + | |
| − | * [[ACETYL-COA-ACETYLTRANSFER-RXN]]
| + | |
| − | * [[RXN-13870]]
| + | |
| − | * [[AKGDHe2r]]
| + | |
| − | * [[RXN-13112]]
| + | |
| − | * [[ALCOHOL-O-ACETYLTRANSFERASE-RXN]]
| + | |
| − | * [[METHYLACETOACETYLCOATHIOL-RXN]]
| + | |
| − | * [[N-ACETYLTRANSFER-RXN]]
| + | |
| − | * [[ACP-S-ACETYLTRANSFER-RXN]]
| + | |
| − | * [[SUCL_gdp_m]]
| + | |
| − | * [[RXN-15066]]
| + | |
| − | * [[LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN]]
| + | |
| − | * [[SUCCCOASYN-RXN]]
| + | |
| − | * [[ACETALD-DEHYDROG-RXN]]
| + | |
| | == External links == | | == External links == |
| − | * CAS : 85-61-0
| + | {{#set: taxonomic range=TAX-4751}} |
| − | * Wikipedia : Coenzyme_a
| + | {{#set: common name=lipoate biosynthesis and incorporation (yeast)}} |
| − | * METABOLIGHTS : MTBLC57287
| + | {{#set: reaction found=4}} |
| − | * PUBCHEM:
| + | {{#set: reaction not found=3}} |
| − | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25113190 25113190]
| + | |
| − | * KNAPSACK : C00007258
| + | |
| − | * HMDB : HMDB01423
| + | |
| − | * LIGAND-CPD:
| + | |
| − | ** [http://www.genome.jp/dbget-bin/www_bget?C00010 C00010]
| + | |
| − | * CHEBI:
| + | |
| − | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57287 57287]
| + | |
| − | * BIGG : coa
| + | |
| − | {{#set: smiles=CC(C)(C(O)C(=O)NCCC(=O)NCCS)COP(=O)(OP(=O)(OCC1(OC(C(C1OP([O-])(=O)[O-])O)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-]}} | + | |
| − | {{#set: inchi key=InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-J}}
| + | |
| − | {{#set: common name=coenzyme A}} | + | |
| − | {{#set: molecular weight=763.502 }} | + | |
| − | {{#set: common name=CoA|co-A-SH|co-enzyme-A|co-A|HS-CoA}}
| + | |
| − | {{#set: consumed by=RXN-2006|RXN66-483|RXN66-480|RXN-16561|RXN66-469|RXN66-484|RXN-16418|RXN-17116|RXN-1126|RXN0-7248|2.3.1.176-RXN|RXN-14268|RXN-2001|RXN-16389|ACYLCOASYN-RXN|RXN-17791|RXN3O-5304|RXN-11921|RXN-16380|LNLNCACOAL|RXN-10919|RXN-13617|ACETATE--COA-LIGASE-RXN|RXN3O-9780|RXN-10699|RXN-9673|BNorh|RXN-16401|RXN-8988|PYRUVDEH-RXN|RXN-15889|RXN-17795|RXN-13614|DHRT_2mbcoa|RXN-16137|2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|RXN-12978|DHRT_ibcoa|TRANS-RXN0-623|RXN-17799|RXN-17778|RXN-7904|RXN66-474|RXN-10695|RXN-14793|KETOACYLCOATHIOL-RXN|2.3.1.155-RXN|ACCAT|RXN-13290|RXN-11213|RXN66-477|RXN-14799|AKBLIG-RXN|RXN-12184|RXN-14774|RXN-17787|BNor|LNLCCOAL|LINOLENOYL-RXN|RXN0-7239|RXN-12710|RXN-14803|RXN-16393|HOLO-ACP-SYNTH-RXN|R223-RXN|RXN-2902|RXN-11917|RXN-17782|RXN-10700|RXN-10701|RXN-9644|RXN-11246|1.2.1.27-RXN|RXN0-7238|RXN-14394|RXN66-474-R-2-HYDROXYSTEARATE/ATP/CO-A//CPD-14717/AMP/PPI.48.|RXN-14788|6.2.1.34-RXN|2-KETO-ADIPATE-DEHYDROG-RXN|RXN-9623|FACOAL18111Z|ENTDB-RXN|4-COUMARATE--COA-LIGASE-RXN|1.2.1.25-RXN|RXN-16402}}
| + | |
| − | {{#set: produced by=DEPHOSPHOCOAKIN-RXN|IPMS|RXN-10821|3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN|RXN-12565|RXN-17729|FATTY-ACYL-COA-SYNTHASE-RXN|THIOESTER-RXN|RXN-16118|MALSYN-RXN|RXN-3142|RXN-15044|RXN-15045|RXN-15043|RXN0-6948|RXN-17855|RXN-17854|RXN-17857|RXN-17856|RXN-17851|RXN-17850|RXN-17853|RXN-17852|RXN-17859|RXN-17858|RXN-9629|FACOAE1839Z12Z15Z|RXN1G-445|RXN-16100|RXN-1106|RXN3DJ-118|RXN-1101|RXN1G-368|2.3.1.165-RXN|RXN-12547|RXN-9627|RXN-13322|RXN-9632|RXN-9624|2-ISOPROPYLMALATESYN-RXN|RXN-17021|RXN-17023|RXN-7697|DIHYDLIPACETRANS-RXN|RXN-15090|CITSYN-RXN|CSm|RXN-9648|RXN-6384|RXN-1623|CSx|RXN-13721|RXN-13435|RXN-13431|RXN-13430|RXN-16082|ACYL-COA-HYDROLASE-RXN|7KAPSYN-RXN|2.3.1.118-RXN|RXN-9652|RXN-9651|RXN-9650|RXN-17864|RXN-9654|RXN-17860|RXN-17861|RXN-17862|RXN-17863|RXN-9543|RXN-9653|ISOVALERYLCOA-DHLIPOAMIDE-RXN|DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|RXN-16094|RXN-16098|ACACT7m|ACDHmi|ACACT|RXN-13297|RXN-13296|RXN-13295|RXN-13294|HICH|RXN-16017|RXN1G-499|RXN-9666|ARYLAMINE-N-ACETYLTRANSFERASE-RXN|RXN-10708|RXN0-1133|LINOLEOYL-RXN|SERINE-C-PALMITOYLTRANSFERASE-RXN|RXN-17011|RXN-17010|RXN-17019|MALONYL-COA-ACP-TRANSACYL-RXN|ACDHi|ADCPT|2.3.1.180-RXN|RXN-13446|RXN-13442|RXN-13441|RXN-7743|RXN-10059|RXN-17008|RXN-17009|RXN-16032|RXN-12362|RXN-12363|RXN-1381|GLUCOSAMINEPNACETYLTRANS-RXN|RXN-9192|SERINE-O-ACETTRAN-RXN|PALMITOYL-COA-HYDROLASE-RXN}} | + | |
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