Difference between revisions of "Tiso gene 5173"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GCVT-RXN GCVT-RXN] == * direction: ** REVERSIBLE * common name: ** dimethylglycine_dehydrogenase **...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14986 RXN-14986] == * direction: ** LEFT-TO-RIGHT * common name: ** 3-isopropylmalate dehydroge...")
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GCVT-RXN GCVT-RXN] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14986 RXN-14986] ==
 
* direction:
 
* direction:
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** dimethylglycine_dehydrogenase
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** 3-isopropylmalate dehydrogenase
** aminomethyltransferase
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** glycine_cleavage_t-protein_c-terminal_barrel_domain
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** sarcosine_dehydrogenase
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* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/2.1.2.10 EC-2.1.2.10]
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** [http://enzyme.expasy.org/EC/1.1.1.85 EC-1.1.1.85]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[THF-GLU-N]][c] '''+''' 1 [[AMINOMETHYLDIHYDROLIPOYL-GCVH]][c] '''<=>''' 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[DIHYDROLIPOYL-GCVH]][c] '''+''' 1 [[AMMONIUM]][c]
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** 1 [[CPD-1130]][c] '''+''' 1 [[NAD]][c] '''=>''' 1 [[NADH]][c] '''+''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[CPD-3618]][c]
 
* With common name(s):
 
* With common name(s):
** 1 a tetrahydrofolate[c] '''+''' 1 a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine[c] '''<=>''' 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine[c] '''+''' 1 ammonium[c]
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** 1 3-ethylmalate[c] '''+''' 1 NAD+[c] '''=>''' 1 NADH[c] '''+''' 1 CO2[c] '''+''' 1 2-oxovalerate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[Tiso_gene_15700]]
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* [[Tiso_gene_2920]]
** [[pantograph]]-[[esiliculosus]]
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* [[Tiso_gene_14788]]
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** IN-SILICO_ANNOTATION
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***EC-NUMBER
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* [[Tiso_gene_17287]]
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** IN-SILICO_ANNOTATION
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***EC-NUMBER
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** EXPERIMENTAL_ANNOTATION
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***EC-NUMBER
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** [[pantograph]]-[[esiliculosus]]
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* [[Tiso_gene_6882]]
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** [[pantograph]]-[[esiliculosus]]
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* [[Tiso_gene_2717]]
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** IN-SILICO_ANNOTATION
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***EC-NUMBER
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* [[Tiso_gene_19389]]
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** IN-SILICO_ANNOTATION
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***EC-NUMBER
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** EXPERIMENTAL_ANNOTATION
 
** EXPERIMENTAL_ANNOTATION
 
***EC-NUMBER
 
***EC-NUMBER
 
** [[pantograph]]-[[esiliculosus]]
 
** [[pantograph]]-[[esiliculosus]]
 
== Pathways  ==
 
== Pathways  ==
* [[GLYCLEAV-PWY]], glycine cleavage: [http://metacyc.org/META/NEW-IMAGE?object=GLYCLEAV-PWY GLYCLEAV-PWY]
+
* [[PWY-7396]], butanol and isobutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7396 PWY-7396]
** '''3''' reactions found over '''3''' reactions in the full pathway
+
** '''4''' reactions found over '''8''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* [[orthology]]:
 
* [[orthology]]:
 
** [[pantograph]]:
 
** [[pantograph]]:
 
*** [[esiliculosus]]
 
*** [[esiliculosus]]
* [[manual]]:
 
** [[primary_network]]
 
 
* [[annotation]]:
 
* [[annotation]]:
 
** [[pathwaytools]]:
 
** [[pathwaytools]]:
 
*** [[experimental_annotation]]
 
*** [[experimental_annotation]]
*** [[in-silico_annotation]]
 
 
== External links  ==
 
== External links  ==
* RHEA:
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{{#set: direction=LEFT-TO-RIGHT}}
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16945 16945]
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{{#set: common name=3-isopropylmalate dehydrogenase}}
* LIGAND-RXN:
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{{#set: ec number=EC-1.1.1.85}}
** [http://www.genome.jp/dbget-bin/www_bget?R04125 R04125]
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{{#set: gene associated=Tiso_gene_2920}}
* UNIPROT:
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{{#set: in pathway=PWY-7396}}
** [http://www.uniprot.org/uniprot/P25285 P25285]
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** [http://www.uniprot.org/uniprot/P28337 P28337]
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** [http://www.uniprot.org/uniprot/P27248 P27248]
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** [http://www.uniprot.org/uniprot/Q9UZP8 Q9UZP8]
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** [http://www.uniprot.org/uniprot/Q9JVP2 Q9JVP2]
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** [http://www.uniprot.org/uniprot/P48728 P48728]
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** [http://www.uniprot.org/uniprot/P49364 P49364]
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** [http://www.uniprot.org/uniprot/P49095 P49095]
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** [http://www.uniprot.org/uniprot/P49363 P49363]
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** [http://www.uniprot.org/uniprot/P54260 P54260]
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** [http://www.uniprot.org/uniprot/P49361 P49361]
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** [http://www.uniprot.org/uniprot/P49362 P49362]
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** [http://www.uniprot.org/uniprot/O49954 O49954]
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** [http://www.uniprot.org/uniprot/P93256 P93256]
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** [http://www.uniprot.org/uniprot/O32955 O32955]
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{{#set: direction=REVERSIBLE}}
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{{#set: common name=dimethylglycine_dehydrogenase}}
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{{#set: common name=aminomethyltransferase}}
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{{#set: common name=glycine_cleavage_t-protein_c-terminal_barrel_domain}}
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{{#set: common name=sarcosine_dehydrogenase}}
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{{#set: ec number=EC-2.1.2.10}}
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{{#set: gene associated=Tiso_gene_15700|Tiso_gene_14788|Tiso_gene_17287|Tiso_gene_6882|Tiso_gene_2717|Tiso_gene_19389}}
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{{#set: in pathway=GLYCLEAV-PWY}}
+
 
{{#set: reconstruction category=orthology}}
 
{{#set: reconstruction category=orthology}}
 
{{#set: reconstruction tool=pantograph}}
 
{{#set: reconstruction tool=pantograph}}
 
{{#set: reconstruction source=esiliculosus}}
 
{{#set: reconstruction source=esiliculosus}}
{{#set: reconstruction category=manual}}
 
{{#set: reconstruction source=primary_network}}
 
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction tool=pathwaytools}}
{{#set: reconstruction source=experimental_annotation|in-silico_annotation}}
+
{{#set: reconstruction source=experimental_annotation}}

Revision as of 17:24, 10 January 2018

Reaction RXN-14986

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-isopropylmalate dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 3-ethylmalate[c] + 1 NAD+[c] => 1 NADH[c] + 1 CO2[c] + 1 2-oxovalerate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7396, butanol and isobutanol biosynthesis (engineered): PWY-7396
    • 4 reactions found over 8 reactions in the full pathway

Reconstruction information

External links