Difference between revisions of "THRDLCTCAT-PWY"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=GMP GMP] == * smiles: ** C(OP(=O)([O-])[O-])C1(OC(C(O)C(O)1)N3(C=NC2(C(=O)NC(N)=NC=23))) * inch...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** f...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=GMP GMP] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] ==
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* smiles:
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* direction:
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** C(OP(=O)([O-])[O-])C1(OC(C(O)C(O)1)N3(C=NC2(C(=O)NC(N)=NC=23)))
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=RQFCJASXJCIDSX-UUOKFMHZSA-L
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* common name:
 
* common name:
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** GMP
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** folylpolyglutamate_synthase
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* molecular weight:
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* ec number:
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** 361.207   
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** [http://enzyme.expasy.org/EC/6.3.2.12 EC-6.3.2.12]
 
* Synonym(s):
 
* Synonym(s):
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** guanylate
 
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** guanylic acid
 
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** guanosine phosphate
 
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** guanosine 5'-phosphate
 
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** guanosine monophosphate
 
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** guanosine-5'-monophosphate
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[GMP-REDUCT-RXN]]
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* With identifiers:
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* [[GUANYL-KIN-RXN]]
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** 1 [[7-8-DIHYDROPTEROATE]][c] '''+''' 1 [[GLT]][c] '''+''' 1 [[ATP]][c] '''=>''' 1 [[Pi]][c] '''+''' 1 [[DIHYDROFOLATE]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[ADP]][c]
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* [[AGPTf]]
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* With common name(s):
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* [[AGPT]]
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** 1 7,8-dihydropteroate[c] '''+''' 1 L-glutamate[c] '''+''' 1 ATP[c] '''=>''' 1 phosphate[c] '''+''' 1 7,8-dihydrofolate monoglutamate[c] '''+''' 1 H+[c] '''+''' 1 ADP[c]
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* [[RXN-7609]]
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== Reaction(s) known to produce the compound ==
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== Genes associated with this reaction  ==
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* [[RXN-14140]]
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Genes have been associated with this reaction based on different elements listed below.
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* [[GMP-SYN-GLUT-RXN]]
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* [[Tiso_gene_15942]]
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* [[GDPA]]
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** IN-SILICO_ANNOTATION
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* [[NTDP]]
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***AUTOMATED-NAME-MATCH
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* [[GMP-SYN-NH3-RXN]]
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* [[Tiso_gene_92]]
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* [[RXN-14201]]
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** [[pantograph]]-[[synechocystis]]
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* [[GUANOSINE-DIPHOSPHATASE-RXN]]
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== Pathways  ==
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* [[35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN]]
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* [[PWY-6614]], tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6614 PWY-6614]
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== Reaction(s) of unknown directionality ==
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** '''3''' reactions found over '''3''' reactions in the full pathway
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* [[COBALAMINSYN-RXN]]
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== Reconstruction information  ==
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* [[GUANPRIBOSYLTRAN-RXN]]
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* Category: [[orthology]]
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** Source: [[orthology-synechocystis]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 85-32-5
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* RHEA:
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* METABOLIGHTS : MTBLC58115
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23584 23584]
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* PUBCHEM:
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* LIGAND-RXN:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1807035 1807035]
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** [http://www.genome.jp/dbget-bin/www_bget?R02237 R02237]
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* HMDB : HMDB01397
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* UNIPROT:
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/Q9JVC6 Q9JVC6]
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** [http://www.genome.jp/dbget-bin/www_bget?C00144 C00144]
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** [http://www.uniprot.org/uniprot/P43775 P43775]
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* CHEMSPIDER:
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** [http://www.uniprot.org/uniprot/Q9PNK6 Q9PNK6]
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** [http://www.chemspider.com/Chemical-Structure.1413162.html 1413162]
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** [http://www.uniprot.org/uniprot/Q50990 Q50990]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/P08192 P08192]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58115 58115]
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{{#set: direction=LEFT-TO-RIGHT}}
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* BIGG : gmp
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{{#set: common name=folylpolyglutamate_synthase}}
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{{#set: smiles=C(OP(=O)([O-])[O-])C1(OC(C(O)C(O)1)N3(C=NC2(C(=O)NC(N)=NC=23)))}}
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{{#set: ec number=EC-6.3.2.12}}
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{{#set: inchi key=InChIKey=RQFCJASXJCIDSX-UUOKFMHZSA-L}}
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{{#set: gene associated=Tiso_gene_15942|Tiso_gene_92}}
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{{#set: common name=GMP}}
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{{#set: in pathway=PWY-6614}}
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{{#set: molecular weight=361.207    }}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: common name=guanylate|guanylic acid|guanosine phosphate|guanosine 5'-phosphate|guanosine monophosphate|guanosine-5'-monophosphate}}
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{{#set: reconstruction source=annotation-in-silico_annotation|orthology-synechocystis}}
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{{#set: consumed by=GMP-REDUCT-RXN|GUANYL-KIN-RXN|AGPTf|AGPT|RXN-7609}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}
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{{#set: produced by=RXN-14140|GMP-SYN-GLUT-RXN|GDPA|NTDP|GMP-SYN-NH3-RXN|RXN-14201|GUANOSINE-DIPHOSPHATASE-RXN|35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN}}
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{{#set: consumed or produced by=COBALAMINSYN-RXN|GUANPRIBOSYLTRAN-RXN}}
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Revision as of 18:08, 18 March 2018

Reaction DIHYDROFOLATESYNTH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • folylpolyglutamate_synthase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 7,8-dihydropteroate[c] + 1 L-glutamate[c] + 1 ATP[c] => 1 phosphate[c] + 1 7,8-dihydrofolate monoglutamate[c] + 1 H+[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6614, tetrahydrofolate biosynthesis: PWY-6614
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links





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