Difference between revisions of "H2Othu"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADENOSYLCOBALAMIN ADENOSYLCOBALAMIN] == * smiles: ** CC%15(C=C%13(C(N%12(C%14(OC(CO)C(OP([O-])(...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTAMINESYN-RXN GLUTAMINESYN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** glutamine_chl...")
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−
[[Category:Metabolite]]
+
[[Category:Reaction]]
−
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADENOSYLCOBALAMIN ADENOSYLCOBALAMIN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLUTAMINESYN-RXN GLUTAMINESYN-RXN] ==
−
* smiles:
+
* direction:
−
** CC%15(C=C%13(C(N%12(C%14(OC(CO)C(OP([O-])(=O)OC(C)CNC(=O)CCC1(C(CC(N)=O)C2(C4(C)(C(C)(CC(N)=O)C(CCC(=O)N)C3(C(C)=C6(C(CC(=O)N)(C(CCC(N)=O)C5(C=C8(C(C)(C)C(CCC(N)=O)C7(C(C)=C1N2[Co---]([N+]=34)([N+]=56)([N+]=78)(CC9(C(C(O)C(O9)N%10(C=NC%11(C%10=NC=NC=%11N)))O))[N+](=C%12)%13))))C)))))(C))C(O)%14)))=CC(C)=%15))
+
** LEFT-TO-RIGHT
−
* inchi key:
+
−
** InChIKey=ZIHHMGTYZOSFRC-YGHJOQEPSA-L
+
 
* common name:
 
* common name:
−
** adenosylcobalamin
+
** glutamine_chloroplasticmitochondrial
−
* molecular weight:
+
** glutamine_synthase
−
** 1579.596   
+
** glutamine_synthetase
 +
** isochorismatase_hydrolase
 +
* ec number:
 +
** [http://enzyme.expasy.org/EC/6.3.1.2 EC-6.3.1.2]
 
* Synonym(s):
 
* Synonym(s):
−
** coenzyme B12
+
** type I glutamate--ammonia ligase
−
** cobamide coenzyme
+
−
** deoxyadenosylcobalamin
+
−
** cobamamide
+
−
** vitamin B12
+
−
** cobamamid
+
−
** 5,6-dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide
+
−
** (5'-deoxy-5'-adenosyl)cobamide coenzyme
+
−
** (5,6-dimethylbenzimidazolyl)cobamide coenzyme
+
−
** 5'-deoxy-5'-adenosylcobalamin
+
−
** 5'-deoxyadenosyl vitamin B12
+
−
** 5'-deoxyadenosyl-5,6-dimethylbenzimidazolylcobamide
+
−
** 5'-deoxyadenosylcobalamin
+
−
** 5,6-dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide
+
−
** calomide
+
−
** cobalamin coenzyme
+
−
** dibencozide
+
−
** funacomide
+
  
−
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
−
== Reaction(s) known to produce the compound ==
+
* With identifiers:
−
* [[RXN-8770]]
+
** 1 [[AMMONIUM]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[GLT]][c] '''=>''' 1 [[Pi]][c] '''+''' 1 [[GLN]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[ADP]][c]
−
* [[COBALADENOSYLTRANS-RXN]]
+
* With common name(s):
−
== Reaction(s) of unknown directionality ==
+
** 1 ammonium[c] '''+''' 1 ATP[c] '''+''' 1 L-glutamate[c] '''=>''' 1 phosphate[c] '''+''' 1 L-glutamine[c] '''+''' 1 H+[c] '''+''' 1 ADP[c]
−
* [[COBALAMINSYN-RXN]]
+
 
 +
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* [[Tiso_gene_13820]]
 +
** IN-SILICO_ANNOTATION
 +
***EC-NUMBER
 +
** [[pantograph]]-[[synechocystis]]
 +
* [[Tiso_gene_6647]]
 +
** IN-SILICO_ANNOTATION
 +
***EC-NUMBER
 +
* [[Tiso_gene_13754]]
 +
** IN-SILICO_ANNOTATION
 +
***EC-NUMBER
 +
** EXPERIMENTAL_ANNOTATION
 +
***EC-NUMBER
 +
** [[pantograph]]-[[synechocystis]]
 +
* [[Tiso_gene_14842]]
 +
** IN-SILICO_ANNOTATION
 +
***EC-NUMBER
 +
** EXPERIMENTAL_ANNOTATION
 +
***EC-NUMBER
 +
** [[pantograph]]-[[athaliana]]
 +
** [[pantograph]]-[[athaliana]]
 +
** [[pantograph]]-[[athaliana]]
 +
** [[pantograph]]-[[esiliculosus]]
 +
== Pathways  ==
 +
* [[GLNSYN-PWY]], L-glutamine biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=GLNSYN-PWY GLNSYN-PWY]
 +
** '''1''' reactions found over '''1''' reactions in the full pathway
 +
* [[PWY-5675]], nitrate reduction V (assimilatory): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5675 PWY-5675]
 +
** '''2''' reactions found over '''4''' reactions in the full pathway
 +
* [[PWY-381]], nitrate reduction II (assimilatory): [http://metacyc.org/META/NEW-IMAGE?object=PWY-381 PWY-381]
 +
** '''3''' reactions found over '''3''' reactions in the full pathway
 +
* [[PWY-6549]], L-glutamine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6549 PWY-6549]
 +
** '''6''' reactions found over '''9''' reactions in the full pathway
 +
* [[PWY-6964]], ammonia assimilation cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6964 PWY-6964]
 +
** '''2''' reactions found over '''2''' reactions in the full pathway
 +
* [[PWY490-3]], nitrate reduction VI (assimilatory): [http://metacyc.org/META/NEW-IMAGE?object=PWY490-3 PWY490-3]
 +
** '''3''' reactions found over '''4''' reactions in the full pathway
 +
* [[PWY-6963]], ammonia assimilation cycle I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6963 PWY-6963]
 +
** '''4''' reactions found over '''6''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-athaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-synechocystis]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[manual]]
 +
** Source: [[manual-primary_network]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* CAS : 13870-90-1
+
* RHEA:
−
* METABOLIGHTS : MTBLC18408
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16169 16169]
−
* PUBCHEM:
+
* LIGAND-RXN:
−
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=91820207 91820207]
+
** [http://www.genome.jp/dbget-bin/www_bget?R00253 R00253]
−
* HMDB : HMDB02086
+
* UNIPROT:
−
* LIGAND-CPD:
+
** [http://www.uniprot.org/uniprot/P15103 P15103]
−
** [http://www.genome.jp/dbget-bin/www_bget?C00194 C00194]
+
** [http://www.uniprot.org/uniprot/P15124 P15124]
−
* CHEBI:
+
** [http://www.uniprot.org/uniprot/P15623 P15623]
−
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=18408 18408]
+
** [http://www.uniprot.org/uniprot/P21154 P21154]
−
* BIGG : adocbl
+
** [http://www.uniprot.org/uniprot/P45627 P45627]
−
{{#set: smiles=CC%15(C=C%13(C(N%12(C%14(OC(CO)C(OP([O-])(=O)OC(C)CNC(=O)CCC1(C(CC(N)=O)C2(C4(C)(C(C)(CC(N)=O)C(CCC(=O)N)C3(C(C)=C6(C(CC(=O)N)(C(CCC(N)=O)C5(C=C8(C(C)(C)C(CCC(N)=O)C7(C(C)=C1N2[Co---]([N+]=34)([N+]=56)([N+]=78)(CC9(C(C(O)C(O9)N%10(C=NC%11(C%10=NC=NC=%11N)))O))[N+](=C%12)%13))))C)))))(C))C(O)%14)))=CC(C)=%15))}}
+
** [http://www.uniprot.org/uniprot/Q59982 Q59982]
−
{{#set: inchi key=InChIKey=ZIHHMGTYZOSFRC-YGHJOQEPSA-L}}
+
** [http://www.uniprot.org/uniprot/Q7M314 Q7M314]
−
{{#set: common name=adenosylcobalamin}}
+
** [http://www.uniprot.org/uniprot/Q60182 Q60182]
−
{{#set: molecular weight=1579.596    }}
+
** [http://www.uniprot.org/uniprot/P04078 P04078]
−
{{#set: common name=coenzyme B12|cobamide coenzyme|deoxyadenosylcobalamin|cobamamide|vitamin B12|cobamamid|5,6-dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide|(5'-deoxy-5'-adenosyl)cobamide coenzyme|(5,6-dimethylbenzimidazolyl)cobamide coenzyme|5'-deoxy-5'-adenosylcobalamin|5'-deoxyadenosyl vitamin B12|5'-deoxyadenosyl-5,6-dimethylbenzimidazolylcobamide|5'-deoxyadenosylcobalamin|5,6-dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide|calomide|cobalamin coenzyme|dibencozide|funacomide}}
+
** [http://www.uniprot.org/uniprot/P00964 P00964]
−
{{#set: produced by=RXN-8770|COBALADENOSYLTRANS-RXN}}
+
** [http://www.uniprot.org/uniprot/P22248 P22248]
−
{{#set: consumed or produced by=COBALAMINSYN-RXN}}
+
** [http://www.uniprot.org/uniprot/P07804 P07804]
 +
** [http://www.uniprot.org/uniprot/P13564 P13564]
 +
** [http://www.uniprot.org/uniprot/P12425 P12425]
 +
** [http://www.uniprot.org/uniprot/P19064 P19064]
 +
** [http://www.uniprot.org/uniprot/P16580 P16580]
 +
** [http://www.uniprot.org/uniprot/P10656 P10656]
 +
** [http://www.uniprot.org/uniprot/P11600 P11600]
 +
** [http://www.uniprot.org/uniprot/P0A1P6 P0A1P6]
 +
** [http://www.uniprot.org/uniprot/P0A9C5 P0A9C5]
 +
** [http://www.uniprot.org/uniprot/P00965 P00965]
 +
** [http://www.uniprot.org/uniprot/P04771 P04771]
 +
** [http://www.uniprot.org/uniprot/P04770 P04770]
 +
** [http://www.uniprot.org/uniprot/P15102 P15102]
 +
** [http://www.uniprot.org/uniprot/P10583 P10583]
 +
** [http://www.uniprot.org/uniprot/P23712 P23712]
 +
** [http://www.uniprot.org/uniprot/P15105 P15105]
 +
** [http://www.uniprot.org/uniprot/P08282 P08282]
 +
** [http://www.uniprot.org/uniprot/P08281 P08281]
 +
** [http://www.uniprot.org/uniprot/P07694 P07694]
 +
** [http://www.uniprot.org/uniprot/P09606 P09606]
 +
** [http://www.uniprot.org/uniprot/P14654 P14654]
 +
** [http://www.uniprot.org/uniprot/P14655 P14655]
 +
** [http://www.uniprot.org/uniprot/P14656 P14656]
 +
** [http://www.uniprot.org/uniprot/P22878 P22878]
 +
** [http://www.uniprot.org/uniprot/P19432 P19432]
 +
** [http://www.uniprot.org/uniprot/P15106 P15106]
 +
** [http://www.uniprot.org/uniprot/P19904 P19904]
 +
** [http://www.uniprot.org/uniprot/P14636 P14636]
 +
** [http://www.uniprot.org/uniprot/P04772 P04772]
 +
** [http://www.uniprot.org/uniprot/P09826 P09826]
 +
** [http://www.uniprot.org/uniprot/P05457 P05457]
 +
** [http://www.uniprot.org/uniprot/Q9JSU6 Q9JSU6]
 +
** [http://www.uniprot.org/uniprot/Q9PPK8 Q9PPK8]
 +
** [http://www.uniprot.org/uniprot/O66514 O66514]
 +
** [http://www.uniprot.org/uniprot/Q8X7G0 Q8X7G0]
 +
** [http://www.uniprot.org/uniprot/Q9CDL9 Q9CDL9]
 +
** [http://www.uniprot.org/uniprot/Q05650 Q05650]
 +
** [http://www.uniprot.org/uniprot/P43794 P43794]
 +
** [http://www.uniprot.org/uniprot/P31592 P31592]
 +
** [http://www.uniprot.org/uniprot/Q27747 Q27747]
 +
** [http://www.uniprot.org/uniprot/P12424 P12424]
 +
** [http://www.uniprot.org/uniprot/Q04831 Q04831]
 +
** [http://www.uniprot.org/uniprot/P24099 P24099]
 +
** [http://www.uniprot.org/uniprot/O04998 O04998]
 +
** [http://www.uniprot.org/uniprot/O04999 O04999]
 +
** [http://www.uniprot.org/uniprot/P20479 P20479]
 +
** [http://www.uniprot.org/uniprot/O75014 O75014]
 +
** [http://www.uniprot.org/uniprot/P23794 P23794]
 +
** [http://www.uniprot.org/uniprot/Q43127 Q43127]
 +
** [http://www.uniprot.org/uniprot/Q9FHR0 Q9FHR0]
 +
** [http://www.uniprot.org/uniprot/Q9C8C7 Q9C8C7]
 +
** [http://www.uniprot.org/uniprot/P28786 P28786]
 +
** [http://www.uniprot.org/uniprot/Q02154 Q02154]
 +
** [http://www.uniprot.org/uniprot/Q05542 Q05542]
 +
** [http://www.uniprot.org/uniprot/Q42624 Q42624]
 +
** [http://www.uniprot.org/uniprot/P43518 P43518]
 +
** [http://www.uniprot.org/uniprot/P52783 P52783]
 +
** [http://www.uniprot.org/uniprot/Q43759 Q43759]
 +
** [http://www.uniprot.org/uniprot/P38559 P38559]
 +
** [http://www.uniprot.org/uniprot/P38560 P38560]
 +
** [http://www.uniprot.org/uniprot/P38561 P38561]
 +
** [http://www.uniprot.org/uniprot/P38562 P38562]
 +
** [http://www.uniprot.org/uniprot/P38563 P38563]
 +
** [http://www.uniprot.org/uniprot/P25462 P25462]
 +
** [http://www.uniprot.org/uniprot/Q42625 Q42625]
 +
** [http://www.uniprot.org/uniprot/P46410 P46410]
 +
** [http://www.uniprot.org/uniprot/Q42802 Q42802]
 +
** [http://www.uniprot.org/uniprot/Q42623 Q42623]
 +
** [http://www.uniprot.org/uniprot/Q53045 Q53045]
 +
** [http://www.uniprot.org/uniprot/P32288 P32288]
 +
** [http://www.uniprot.org/uniprot/Q43066 Q43066]
 +
** [http://www.uniprot.org/uniprot/Q59195 Q59195]
 +
** [http://www.uniprot.org/uniprot/P51118 P51118]
 +
** [http://www.uniprot.org/uniprot/P51119 P51119]
 +
** [http://www.uniprot.org/uniprot/Q42950 Q42950]
 +
** [http://www.uniprot.org/uniprot/Q42951 Q42951]
 +
** [http://www.uniprot.org/uniprot/Q07939 Q07939]
 +
** [http://www.uniprot.org/uniprot/Q43760 Q43760]
 +
** [http://www.uniprot.org/uniprot/Q42688 Q42688]
 +
** [http://www.uniprot.org/uniprot/Q42689 Q42689]
 +
** [http://www.uniprot.org/uniprot/O22504 O22504]
 +
** [http://www.uniprot.org/uniprot/O22505 O22505]
 +
** [http://www.uniprot.org/uniprot/O22506 O22506]
 +
** [http://www.uniprot.org/uniprot/Q59972 Q59972]
 +
** [http://www.uniprot.org/uniprot/Q9UWN1 Q9UWN1]
 +
** [http://www.uniprot.org/uniprot/Q9RDW7 Q9RDW7]
 +
** [http://www.uniprot.org/uniprot/P43386 P43386]
 +
** [http://www.uniprot.org/uniprot/P0A040 P0A040]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: common name=glutamine_chloroplasticmitochondrial}}
 +
{{#set: common name=glutamine_synthase}}
 +
{{#set: common name=glutamine_synthetase}}
 +
{{#set: common name=isochorismatase_hydrolase}}
 +
{{#set: ec number=EC-6.3.1.2}}
 +
{{#set: common name=type I glutamate--ammonia ligase}}
 +
{{#set: gene associated=Tiso_gene_13820|Tiso_gene_6647|Tiso_gene_13754|Tiso_gene_14842}}
 +
{{#set: in pathway=GLNSYN-PWY|PWY-5675|PWY-381|PWY-6549|PWY-6964|PWY490-3|PWY-6963}}
 +
{{#set: reconstruction category=orthology|manual|annotation}}
 +
{{#set: reconstruction source=annotation-experimental_annotation|orthology-esiliculosus|annotation-in-silico_annotation|orthology-athaliana|orthology-synechocystis|manual-primary_network}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Revision as of 18:19, 18 March 2018

Reaction GLUTAMINESYN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • glutamine_chloroplasticmitochondrial
    • glutamine_synthase
    • glutamine_synthetase
    • isochorismatase_hydrolase
  • ec number:
  • Synonym(s):
    • type I glutamate--ammonia ligase

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 ammonium[c] + 1 ATP[c] + 1 L-glutamate[c] => 1 phosphate[c] + 1 L-glutamine[c] + 1 H+[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • GLNSYN-PWY, L-glutamine biosynthesis I: GLNSYN-PWY
    • 1 reactions found over 1 reactions in the full pathway
  • PWY-5675, nitrate reduction V (assimilatory): PWY-5675
    • 2 reactions found over 4 reactions in the full pathway
  • PWY-381, nitrate reduction II (assimilatory): PWY-381
    • 3 reactions found over 3 reactions in the full pathway
  • PWY-6549, L-glutamine biosynthesis III: PWY-6549
    • 6 reactions found over 9 reactions in the full pathway
  • PWY-6964, ammonia assimilation cycle II: PWY-6964
    • 2 reactions found over 2 reactions in the full pathway
  • PWY490-3, nitrate reduction VI (assimilatory): PWY490-3
    • 3 reactions found over 4 reactions in the full pathway
  • PWY-6963, ammonia assimilation cycle I: PWY-6963
    • 4 reactions found over 6 reactions in the full pathway

Reconstruction information

External links







Retrieved from "http://gem-aureme.irisa.fr/tisogem/index.php?title=H2Othu&oldid=23519"