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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Aliphatic-Amines Aliphatic-Amines] == |
− | * direction:
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− | ** REVERSIBLE
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| * common name: | | * common name: |
− | ** polyketide_synthase | + | ** an aliphatic amine |
− | * ec number:
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− | ** [http://enzyme.expasy.org/EC/2.3.3.10 EC-2.3.3.10]
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| * Synonym(s): | | * Synonym(s): |
| + | ** RCH2NH2 |
| + | ** RCH(2)NH(2) |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | * [[AMINEOXID-RXN]] |
− | ** 1 [[ACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''+''' 1 [[ACETOACETYL-COA]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 1 [[CO-A]][c]
| + | == Reaction(s) known to produce the compound == |
− | * With common name(s):
| + | == Reaction(s) of unknown directionality == |
− | ** 1 acetyl-CoA[c] '''+''' 1 H2O[c] '''+''' 1 acetoacetyl-CoA[c] '''<=>''' 1 H+[c] '''+''' 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''+''' 1 coenzyme A[c]
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− | | + | |
− | == Genes associated with this reaction == | + | |
− | Genes have been associated with this reaction based on different elements listed below.
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− | * [[Tiso_gene_14303]] | + | |
− | ** [[pantograph]]-[[athaliana]]
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− | ** [[pantograph]]-[[esiliculosus]]
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− | * [[Tiso_gene_9236]]
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− | ** IN-SILICO_ANNOTATION
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− | ***EC-NUMBER
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− | * [[Tiso_gene_8563]]
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− | ** [[pantograph]]-[[esiliculosus]]
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− | == Pathways == | + | |
− | * [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
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− | ** '''5''' reactions found over '''5''' reactions in the full pathway
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− | * [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
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− | ** '''5''' reactions found over '''7''' reactions in the full pathway
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− | * [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922]
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− | ** '''6''' reactions found over '''7''' reactions in the full pathway
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− | * [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
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− | ** '''6''' reactions found over '''8''' reactions in the full pathway
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− | * [[PWY-7571]], ferrichrome A biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7571 PWY-7571]
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− | ** '''2''' reactions found over '''5''' reactions in the full pathway
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− | * [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
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− | ** '''4''' reactions found over '''8''' reactions in the full pathway
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− | == Reconstruction information == | + | |
− | * Category: [[orthology]]
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− | ** Source: [[orthology-athaliana]]
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− | *** Tool: [[pantograph]]
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− | ** Source: [[orthology-esiliculosus]]
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− | *** Tool: [[pantograph]]
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− | * Category: [[annotation]]
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− | ** Source: [[annotation-in-silico_annotation]]
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− | *** Tool: [[pathwaytools]]
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| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=an aliphatic amine}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10188 10188]
| + | {{#set: common name=RCH2NH2|RCH(2)NH(2)}} |
− | * LIGAND-RXN:
| + | {{#set: consumed by=AMINEOXID-RXN}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R01978 R01978]
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− | * UNIPROT:
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− | ** [http://www.uniprot.org/uniprot/P13704 P13704]
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− | ** [http://www.uniprot.org/uniprot/P22791 P22791]
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− | ** [http://www.uniprot.org/uniprot/P54870 P54870]
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− | ** [http://www.uniprot.org/uniprot/P54869 P54869]
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− | ** [http://www.uniprot.org/uniprot/O51626 O51626]
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− | ** [http://www.uniprot.org/uniprot/Q9CFA9 Q9CFA9]
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− | ** [http://www.uniprot.org/uniprot/P17425 P17425]
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− | ** [http://www.uniprot.org/uniprot/Q7LZE7 Q7LZE7]
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− | ** [http://www.uniprot.org/uniprot/Q01581 Q01581]
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− | ** [http://www.uniprot.org/uniprot/P54961 P54961]
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− | ** [http://www.uniprot.org/uniprot/P54839 P54839]
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− | ** [http://www.uniprot.org/uniprot/P54874 P54874]
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− | ** [http://www.uniprot.org/uniprot/P54868 P54868]
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− | ** [http://www.uniprot.org/uniprot/P54873 P54873]
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− | ** [http://www.uniprot.org/uniprot/P93773 P93773]
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− | {{#set: direction=REVERSIBLE}} | + | |
− | {{#set: common name=polyketide_synthase}} | + | |
− | {{#set: ec number=EC-2.3.3.10}}
| + | |
− | {{#set: gene associated=Tiso_gene_14303|Tiso_gene_9236|Tiso_gene_8563}} | + | |
− | {{#set: in pathway=PWY66-367|PWY-6174|PWY-922|PWY-7391|PWY-7571|PWY-7524}}
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− | {{#set: reconstruction category=orthology|annotation}}
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− | {{#set: reconstruction source=orthology-athaliana|annotation-in-silico_annotation|orthology-esiliculosus}}
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− | {{#set: reconstruction tool=pantograph|pathwaytools}}
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