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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GCVT-RXN GCVT-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=Odd-Straight-Chain-234-Sat-FA Odd-Straight-Chain-234-Sat-FA] == |
− | * direction:
| + | |
− | ** REVERSIBLE
| + | |
| * common name: | | * common name: |
− | ** dimethylglycine_dehydrogenase | + | ** an odd numbered straight chain 2,3,4-saturated fatty acid |
− | ** aminomethyltransferase
| + | |
− | ** glycine_cleavage_t-protein_c-terminal_barrel_domain
| + | |
− | ** sarcosine_dehydrogenase
| + | |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/2.1.2.10 EC-2.1.2.10]
| + | |
| * Synonym(s): | | * Synonym(s): |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | * [[RXN66-477]] |
− | ** 1 [[AMINOMETHYLDIHYDROLIPOYL-GCVH]][c] '''+''' 1 [[THF-GLU-N]][c] '''<=>''' 1 [[AMMONIUM]][c] '''+''' 1 [[DIHYDROLIPOYL-GCVH]][c] '''+''' 1 [[METHYLENE-THF-GLU-N]][c]
| + | == Reaction(s) known to produce the compound == |
− | * With common name(s):
| + | * [[RXN66-476]] |
− | ** 1 a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine[c] '''+''' 1 a tetrahydrofolate[c] '''<=>''' 1 ammonium[c] '''+''' 1 a [glycine-cleavage complex H protein] N6-dihydrolipoyl-L-lysine[c] '''+''' 1 a 5,10-methylene-tetrahydrofolate[c]
| + | == Reaction(s) of unknown directionality == |
− | | + | |
− | == Genes associated with this reaction == | + | |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * [[Tiso_gene_6882]] | + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_14788]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | * [[Tiso_gene_17287]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** EXPERIMENTAL_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_15700]]
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | * [[Tiso_gene_2717]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | * [[Tiso_gene_19389]]
| + | |
− | ** IN-SILICO_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** EXPERIMENTAL_ANNOTATION
| + | |
− | ***EC-NUMBER
| + | |
− | ** [[pantograph]]-[[esiliculosus]]
| + | |
− | == Pathways == | + | |
− | * [[GLYCLEAV-PWY]], glycine cleavage: [http://metacyc.org/META/NEW-IMAGE?object=GLYCLEAV-PWY GLYCLEAV-PWY] | + | |
− | ** '''3''' reactions found over '''3''' reactions in the full pathway
| + | |
− | == Reconstruction information == | + | |
− | * Category: [[orthology]]
| + | |
− | ** Source: [[orthology-esiliculosus]]
| + | |
− | *** Tool: [[pantograph]]
| + | |
− | * Category: [[manual]]
| + | |
− | ** Source: [[manual-primary_network]]
| + | |
− | * Category: [[annotation]]
| + | |
− | ** Source: [[annotation-experimental_annotation]]
| + | |
− | *** Tool: [[pathwaytools]]
| + | |
− | ** Source: [[annotation-in-silico_annotation]]
| + | |
− | *** Tool: [[pathwaytools]]
| + | |
| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=an odd numbered straight chain 2,3,4-saturated fatty acid}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=16945 16945]
| + | {{#set: consumed by=RXN66-477}} |
− | * LIGAND-RXN:
| + | {{#set: produced by=RXN66-476}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R04125 R04125]
| + | |
− | * UNIPROT:
| + | |
− | ** [http://www.uniprot.org/uniprot/P25285 P25285]
| + | |
− | ** [http://www.uniprot.org/uniprot/P28337 P28337]
| + | |
− | ** [http://www.uniprot.org/uniprot/P27248 P27248]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9UZP8 Q9UZP8]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9JVP2 Q9JVP2]
| + | |
− | ** [http://www.uniprot.org/uniprot/P48728 P48728]
| + | |
− | ** [http://www.uniprot.org/uniprot/P49364 P49364]
| + | |
− | ** [http://www.uniprot.org/uniprot/P49095 P49095]
| + | |
− | ** [http://www.uniprot.org/uniprot/P49363 P49363]
| + | |
− | ** [http://www.uniprot.org/uniprot/P54260 P54260]
| + | |
− | ** [http://www.uniprot.org/uniprot/P49361 P49361]
| + | |
− | ** [http://www.uniprot.org/uniprot/P49362 P49362]
| + | |
− | ** [http://www.uniprot.org/uniprot/O49954 O49954]
| + | |
− | ** [http://www.uniprot.org/uniprot/P93256 P93256]
| + | |
− | ** [http://www.uniprot.org/uniprot/O32955 O32955]
| + | |
− | {{#set: direction=REVERSIBLE}}
| + | |
− | {{#set: common name=dimethylglycine_dehydrogenase}} | + | |
− | {{#set: common name=aminomethyltransferase}}
| + | |
− | {{#set: common name=glycine_cleavage_t-protein_c-terminal_barrel_domain}}
| + | |
− | {{#set: common name=sarcosine_dehydrogenase}} | + | |
− | {{#set: ec number=EC-2.1.2.10}}
| + | |
− | {{#set: gene associated=Tiso_gene_6882|Tiso_gene_14788|Tiso_gene_17287|Tiso_gene_15700|Tiso_gene_2717|Tiso_gene_19389}} | + | |
− | {{#set: in pathway=GLYCLEAV-PWY}}
| + | |
− | {{#set: reconstruction category=orthology|manual|annotation}}
| + | |
− | {{#set: reconstruction source=annotation-experimental_annotation|manual-primary_network|annotation-in-silico_annotation|orthology-esiliculosus}}
| + | |
− | {{#set: reconstruction tool=pantograph|pathwaytools}}
| + | |