Difference between revisions of "PROPIONYL-COA"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12037 RXN-12037] == * direction: ** LEFT-TO-RIGHT * common name: ** 3',5'-diiodothyronine 5'-de...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN] == * direction: ** L...")
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12037 RXN-12037] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
−
** 3',5'-diiodothyronine 5'-deiodinase
+
** 3-hydroxyisobutyrate_mitochondrial
−
** type_i_iodothyronine_deiodinase
+
** 3-hydroxyisobutyrate_dehydrogenase
 +
** uncharacterized_oxidoreductase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/1.21.99.4 EC-1.21.99.4]
+
** [http://enzyme.expasy.org/EC/1.1.1.31 EC-1.1.1.31]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[Donor-H2]][c] '''+''' 1 [[CPD-13008]][c] '''=>''' 1 [[CPD-387]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[CPD-13010]][c] '''+''' 1 [[Acceptor]][c]
+
** 1 [[NAD]][c] '''+''' 1 [[CPD-12175]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[CH3-MALONATE-S-ALD]][c] '''+''' 1 [[NADH]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 a reduced electron acceptor[c] '''+''' 1 3',5'-diiodothyronine[c] '''=>''' 1 iodide[c] '''+''' 1 H+[c] '''+''' 1 3'-monoiodothyronine[c] '''+''' 1 an oxidized electron acceptor[c]
+
** 1 NAD+[c] '''+''' 1 (S)-3-hydroxy-isobutanoate[c] '''=>''' 1 H+[c] '''+''' 1 (S)-methylmalonate-semialdehyde[c] '''+''' 1 NADH[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[Tiso_gene_20481]]
+
* Gene: [[Tiso_gene_7107]]
−
** IN-SILICO_ANNOTATION
+
** Source: [[annotation-in-silico_annotation]]
−
***EC-NUMBER
+
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[Tiso_gene_19772]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_5857]]
 +
** Source: [[orthology-athaliana]]
 +
** Source: [[orthology-creinhardtii]]
 +
* Gene: [[Tiso_gene_19592]]
 +
** Source: [[orthology-esiliculosus]]
 +
** Source: [[orthology-creinhardtii]]
 +
* Gene: [[Tiso_gene_19590]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
** Source: [[orthology-esiliculosus]]
 +
** Source: [[orthology-creinhardtii]]
 +
* Gene: [[Tiso_gene_19771]]
 +
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-6260]], thyroid hormone metabolism I (via deiodination): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6260 PWY-6260]
+
* [[VALDEG-PWY]], L-valine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=VALDEG-PWY VALDEG-PWY]
−
** '''3''' reactions found over '''12''' reactions in the full pathway
+
** '''8''' reactions found over '''8''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-athaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-creinhardtii]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-esiliculosus]]
 +
*** Tool: [[pantograph]]
 
* Category: [[annotation]]
 
* Category: [[annotation]]
 +
** Source: [[annotation-experimental_annotation]]
 +
*** Tool: [[pathwaytools]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R02047 R02047]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P29266 P29266]
 +
** [http://www.uniprot.org/uniprot/P28811 P28811]
 +
** [http://www.uniprot.org/uniprot/Q8XAE4 Q8XAE4]
 +
** [http://www.uniprot.org/uniprot/Q55702 Q55702]
 +
** [http://www.uniprot.org/uniprot/Q9XTI0 Q9XTI0]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: common name=3',5'-diiodothyronine 5'-deiodinase}}
+
{{#set: common name=3-hydroxyisobutyrate_mitochondrial}}
−
{{#set: common name=type_i_iodothyronine_deiodinase}}
+
{{#set: common name=3-hydroxyisobutyrate_dehydrogenase}}
−
{{#set: ec number=EC-1.21.99.4}}
+
{{#set: common name=uncharacterized_oxidoreductase}}
−
{{#set: gene associated=Tiso_gene_20481}}
+
{{#set: ec number=EC-1.1.1.31}}
−
{{#set: in pathway=PWY-6260}}
+
{{#set: gene associated=Tiso_gene_7107|Tiso_gene_19772|Tiso_gene_5857|Tiso_gene_19592|Tiso_gene_19590|Tiso_gene_19771}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: in pathway=VALDEG-PWY}}
−
{{#set: reconstruction source=annotation-in-silico_annotation}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction source=orthology-creinhardtii|orthology-athaliana|annotation-in-silico_annotation|orthology-esiliculosus|annotation-experimental_annotation}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Revision as of 16:05, 21 March 2018

Reaction 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-hydroxyisobutyrate_mitochondrial
    • 3-hydroxyisobutyrate_dehydrogenase
    • uncharacterized_oxidoreductase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NAD+[c] + 1 (S)-3-hydroxy-isobutanoate[c] => 1 H+[c] + 1 (S)-methylmalonate-semialdehyde[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • VALDEG-PWY, L-valine degradation I: VALDEG-PWY
    • 8 reactions found over 8 reactions in the full pathway

Reconstruction information

External links






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