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Line 1: |
Line 1: |
− | [[Category:Metabolite]] | + | [[Category:Reaction]] |
− | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PPI PPI] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-5515 RXN0-5515] == |
− | * smiles: | + | * direction: |
− | ** O=P(O)(OP([O-])([O-])=O)[O-] | + | ** LEFT-TO-RIGHT |
| * common name: | | * common name: |
− | ** diphosphate | + | ** phosphatidate_cytidylyltransferase |
− | * inchi key: | + | * ec number: |
− | ** InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K | + | ** [http://enzyme.expasy.org/EC/2.7.7.41 EC-2.7.7.41] |
− | * molecular weight:
| + | |
− | ** 174.951
| + | |
| * Synonym(s): | | * Synonym(s): |
− | ** PPi
| |
− | ** PP
| |
− | ** pyrophosphate
| |
| | | |
− | == Reaction(s) known to consume the compound == | + | == Reaction Formula == |
− | * [[INORGPYROPHOSPHAT-RXN]] | + | * With identifiers: |
− | == Reaction(s) known to produce the compound ==
| + | ** 1 [[2-3-4-Saturated-L-Phosphatidates]][c] '''+''' 1 [[CTP]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CDP-2-3-4-Saturated-Diacylglycerols]][c] '''+''' 1 [[PPI]][c] |
− | * [[ARGININE--TRNA-LIGASE-RXN]] | + | * With common name(s): |
− | * [[RXN66-483]]
| + | ** 1 a 1,2-diacyl-sn-glycerol 3-phosphate[c] '''+''' 1 CTP[c] '''+''' 1 H+[c] '''=>''' 1 a CDP-2,3,4-saturated-diacylglycerol[c] '''+''' 1 diphosphate[c] |
− | * [[RXN66-480]]
| + | |
− | * [[RXN-7663]]
| + | == Genes associated with this reaction == |
− | * [[RXN0-1602]]
| + | Genes have been associated with this reaction based on different elements listed below. |
− | * [[RXN66-484]]
| + | * Gene: [[Tiso_gene_2311]] |
− | * [[RXN0-2023]]
| + | ** Source: [[annotation-in-silico_annotation]] |
− | * [[GMP-SYN-GLUT-RXN]]
| + | *** Assignment: AUTOMATED-NAME-MATCH |
− | * [[RXN66-555]]
| + | * Gene: [[Tiso_gene_3522]] |
− | * [[RXN0-7248]]
| + | ** Source: [[orthology-esiliculosus]] |
− | * [[R06284]]
| + | * Gene: [[Tiso_gene_3523]] |
− | * [[ACYLCOASYN-RXN]]
| + | ** Source: [[orthology-esiliculosus]] |
− | * [[ACETATE--COA-LIGASE-RXN]]
| + | == Pathways == |
− | * [[DIPHTINE--AMMONIA-LIGASE-RXN]]
| + | == Reconstruction information == |
− | * [[DCTP-PYROPHOSPHATASE-RXN]]
| + | * Category: [[orthology]] |
− | * [[ASPARTATE--TRNA-LIGASE-RXN]]
| + | ** Source: [[orthology-esiliculosus]] |
− | * [[2.5.1.32-RXN]] | + | *** Tool: [[pantograph]] |
− | * [[THI-P-SYN-RXN]]
| + | * Category: [[annotation]] |
− | * [[R223-RXN]]
| + | ** Source: [[annotation-in-silico_annotation]] |
− | * [[RXN-11486]]
| + | *** Tool: [[pathwaytools]] |
− | * [[HISTPRATPHYD-RXN]]
| + | |
− | * [[URACIL-PRIBOSYLTRANS-RXN]]
| + | |
− | * [[URITRANS-RXN]]
| + | |
− | * [[RXN0-1141]]
| + | |
− | * [[TRYPTOPHAN--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN-7904]]
| + | |
− | * [[RXN-16418]]
| + | |
− | * [[TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN]]
| + | |
− | * [[RXN-7674]]
| + | |
− | * [[6.1.1.24-RXN]]
| + | |
− | * [[RXN0-383]]
| + | |
− | * [[RXN0-384]]
| + | |
− | * [[ASNSYNA-RXN]]
| + | |
− | * [[DNA-LIGASE-ATP-RXN]]
| + | |
− | * [[LYSINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN0-6274]]
| + | |
− | * [[UBIQUITIN--PROTEIN-LIGASE-RXN]]
| + | |
− | * [[NUCLEOTIDE-PYROPHOSPHATASE-RXN]]
| + | |
− | * [[RXN-12611]]
| + | |
− | * [[PANTEPADENYLYLTRAN-RXN]]
| + | |
− | * [[RXN-14139]]
| + | |
− | * [[RXN-9386]]
| + | |
− | * [[RXN-9623]]
| + | |
− | * [[2.5.1.39-RXN]]
| + | |
− | * [[4-COUMARATE--COA-LIGASE-RXN]]
| + | |
− | * [[RXN-8654]]
| + | |
− | * [[ASPARAGINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[GLUTAMINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[GPPS]]
| + | |
− | * [[GLCUR1PUT]]
| + | |
− | * [[6.3.4.10-RXN]]
| + | |
− | * [[ARGSUCCINSYN-RXN]]
| + | |
− | * [[RXN-2001]]
| + | |
− | * [[2.7.7.13-RXN]]
| + | |
− | * [[DGTD]]
| + | |
− | * [[THREONINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN-17917]]
| + | |
− | * [[GGPS]]
| + | |
− | * [[METHIONINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[6.2.1.34-RXN]]
| + | |
− | * [[XANPRIBOSYLTRAN-RXN]]
| + | |
− | * [[RXN-12978]]
| + | |
− | * [[NICONUCADENYLYLTRAN-RXN]]
| + | |
− | * [[RXN-10919]]
| + | |
− | * [[RXN-4305]]
| + | |
− | * [[FADSYN-RXN]]
| + | |
− | * [[ALANINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN-14140]]
| + | |
− | * [[RME256]]
| + | |
− | * [[RME255]]
| + | |
− | * [[RXN0-5107]]
| + | |
− | * [[DNA-DIRECTED-DNA-POLYMERASE-RXN]]
| + | |
− | * [[RXN0-7239]]
| + | |
− | * [[UTPPH]]
| + | |
− | * [[RXN0-2161]]
| + | |
− | * [[4OHBENZOATE-OCTAPRENYLTRANSFER-RXN]]
| + | |
− | * [[RXN-9644]]
| + | |
− | * [[GSADENYLATION-RXN]]
| + | |
− | * [[RXN0-7238]]
| + | |
− | * [[RXN-12720]]
| + | |
− | * [[ADENYLATECYC-RXN]]
| + | |
− | * [[PROLINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[NTPD]]
| + | |
− | * [[2.7.7.14-RXN]]
| + | |
− | * [[QUINOPRIBOTRANS-RXN]]
| + | |
− | * [[VALINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN-1126]]
| + | |
− | * [[S-ADENMETSYN-RXN]]
| + | |
− | * [[RXN-16165]]
| + | |
− | * [[UG1PUT]]
| + | |
− | * [[H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN]]
| + | |
− | * [[FPPSYN-RXN]]
| + | |
− | * [[DUTNH]]
| + | |
− | * [[FARNESYLTRANSTRANSFERASE-RXN]]
| + | |
− | * [[P-PANTOCYSLIG-RXN]]
| + | |
− | * [[RXN66-477]]
| + | |
− | * [[HISTIDINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN66-474]]
| + | |
− | * [[RXN-12184]]
| + | |
− | * [[RXN-13290]]
| + | |
− | * [[RNA-LIGASE-ATP-RXN]]
| + | |
− | * [[TYROSINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[MRNA-GUANYLYLTRANSFERASE-RXN]]
| + | |
− | * [[RXN-16393]]
| + | |
− | * [[RXN-16389]]
| + | |
− | * [[ASNSYNB-RXN]]
| + | |
− | * [[GTP-CYCLOHYDRO-II-RXN]]
| + | |
− | * [[TRANS-RXN0-623]]
| + | |
− | * [[RXN-12610]]
| + | |
− | * [[R06858]]
| + | |
− | * [[2.4.2.12-RXN]]
| + | |
− | * [[H2PTEROATESYNTH-RXN]]
| + | |
− | * [[RXN0-1603]]
| + | |
− | * [[RXN66-474-R-2-HYDROXYSTEARATE/ATP/CO-A//CPD-14717/AMP/PPI.48.]]
| + | |
− | * [[RXN0-5515]]
| + | |
− | * [[RXN-8999]] | + | |
− | * [[GMP-SYN-NH3-RXN]] | + | |
− | * [[NAG1P-URIDYLTRANS-RXN]] | + | |
− | * [[RXNARA-8002]]
| + | |
− | * [[RXN-16401]]
| + | |
− | * [[RXN-16402]]
| + | |
− | * [[RXN66-469]]
| + | |
− | * [[GAMPG]]
| + | |
− | * [[SERINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[LINOLENOYL-RXN]]
| + | |
− | * [[RXN0-6427]]
| + | |
− | * [[PANTOATE-BETA-ALANINE-LIG-RXN]]
| + | |
− | * [[2.7.7.60-RXN]]
| + | |
− | * [[RXN0-7192]]
| + | |
− | * [[RXN-16380]]
| + | |
− | * [[RNA-3-PHOSPHATE-CYCLASE-RXN]]
| + | |
− | * [[RXN-9673]]
| + | |
− | * [[NTDP]]
| + | |
− | * [[CYSTEINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[6.3.4.11-RXN]]
| + | |
− | * [[LEUCINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[RXN-13614]]
| + | |
− | * [[GLYCINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[PHENYLALANINE--TRNA-LIGASE-RXN]]
| + | |
− | * [[ADEC]]
| + | |
− | * [[CDPDIGLYSYN-RXN]]
| + | |
− | * [[LNLNCACOAL]] | + | |
− | * [[RXN-10]] | + | |
− | * [[HYPOXANPRIBOSYLTRAN-RXN]] | + | |
− | * [[RXN-10695]]
| + | |
− | * [[RXN0-5098]] | + | |
− | * [[PRADP]] | + | |
− | * [[ISOLEUCINE--TRNA-LIGASE-RXN]] | + | |
− | * [[RXN-2541]] | + | |
− | * [[RXN-4303]] | + | |
− | * [[6.3.4.9-RXN]] | + | |
− | * [[BIOTINLIG-RXN]] | + | |
− | * [[PPGPPSYN-RXN]] | + | |
− | * [[RXN-17127]] | + | |
− | * [[LNLCCOAL]]
| + | |
− | * [[RXN-12245]]
| + | |
− | * [[RXN-9003]]
| + | |
− | * [[ITPP]]
| + | |
− | * [[RXN-17925]]
| + | |
− | * [[GLURS-RXN]]
| + | |
− | * [[RXN0-6382]]
| + | |
− | * [[FACOAL18111Z]]
| + | |
− | * [[DUTP-PYROP-RXN]]
| + | |
− | * [[RXN0-385]]
| + | |
− | == Reaction(s) of unknown directionality == | + | |
− | * [[RXN1F-144]] | + | |
− | * [[GUANYLCYC-RXN]] | + | |
− | * [[RNA-DIRECTED-DNA-POLYMERASE-RXN]] | + | |
− | * [[ATPPHOSPHORIBOSYLTRANS-RXN]] | + | |
− | * [[RXN-3701]] | + | |
− | * [[GBDP]] | + | |
− | * [[RXN1F-66]] | + | |
− | * [[2.7.7.11-RXN]] | + | |
− | * [[2.5.1.58-RXN]] | + | |
− | * [[TCM3]]
| + | |
− | * [[RXN-13323]]
| + | |
− | * [[OROPRIBTRANS-RXN]] | + | |
− | * [[TCP26]] | + | |
− | * [[SULFATE-ADENYLYLTRANS-RXN]] | + | |
− | * [[RXN0-5180]]
| + | |
− | * [[RXN-16415]]
| + | |
− | * [[RXN-7673]]
| + | |
− | * [[PRTRANS-RXN]]
| + | |
− | * [[PRPPAMIDOTRANS-RXN]]
| + | |
− | * [[UTPHEXPURIDYLYLTRANS-RXN]]
| + | |
− | * [[DNA-DIRECTED-RNA-POLYMERASE-RXN]]
| + | |
− | * [[DTDPGLUCOSEPP-RXN]]
| + | |
− | * [[GUANPRIBOSYLTRAN-RXN]]
| + | |
− | * [[GLUC1PURIDYLTRANS-RXN]]
| + | |
− | * [[orPRT]]
| + | |
− | * [[TCX10]]
| + | |
− | * [[2.7.1.90-RXN]]
| + | |
− | * [[GPPSYN-RXN]]
| + | |
− | * [[POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN]]
| + | |
− | * [[2.7.7.44-RXN]]
| + | |
| == External links == | | == External links == |
− | * CAS : 2466-09-3
| + | {{#set: direction=LEFT-TO-RIGHT}} |
− | * BIGG : ppi
| + | {{#set: common name=phosphatidate_cytidylyltransferase}} |
− | * DRUGBANK : DB04160
| + | {{#set: ec number=EC-2.7.7.41}} |
− | * PUBCHEM:
| + | {{#set: gene associated=Tiso_gene_2311|Tiso_gene_3522|Tiso_gene_3523}} |
− | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1023 1023]
| + | {{#set: in pathway=}} |
− | * HMDB : HMDB00250
| + | {{#set: reconstruction category=orthology|annotation}} |
− | * LIGAND-CPD:
| + | {{#set: reconstruction source=annotation-in-silico_annotation|orthology-esiliculosus}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?C00013 C00013]
| + | {{#set: reconstruction tool=pantograph|pathwaytools}} |
− | * CHEMSPIDER:
| + | |
− | ** [http://www.chemspider.com/Chemical-Structure.996.html 996]
| + | |
− | * CHEBI:
| + | |
− | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=29888 29888]
| + | |
− | * METABOLIGHTS : MTBLC33019
| + | |
− | {{#set: smiles=O=P(O)(OP([O-])([O-])=O)[O-]}} | + | |
− | {{#set: common name=diphosphate}} | + | |
− | {{#set: inchi key=InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-K}} | + | |
− | {{#set: molecular weight=174.951 }} | + | |
− | {{#set: common name=PPi|PP|pyrophosphate}} | + | |
− | {{#set: consumed by=INORGPYROPHOSPHAT-RXN}} | + | |
− | {{#set: produced by=ARGININE--TRNA-LIGASE-RXN|RXN66-483|RXN66-480|RXN-7663|RXN0-1602|RXN66-484|RXN0-2023|GMP-SYN-GLUT-RXN|RXN66-555|RXN0-7248|R06284|ACYLCOASYN-RXN|ACETATE--COA-LIGASE-RXN|DIPHTINE--AMMONIA-LIGASE-RXN|DCTP-PYROPHOSPHATASE-RXN|ASPARTATE--TRNA-LIGASE-RXN|2.5.1.32-RXN|THI-P-SYN-RXN|R223-RXN|RXN-11486|HISTPRATPHYD-RXN|URACIL-PRIBOSYLTRANS-RXN|URITRANS-RXN|RXN0-1141|TRYPTOPHAN--TRNA-LIGASE-RXN|RXN-7904|RXN-16418|TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN|RXN-7674|6.1.1.24-RXN|RXN0-383|RXN0-384|ASNSYNA-RXN|DNA-LIGASE-ATP-RXN|LYSINE--TRNA-LIGASE-RXN|RXN0-6274|UBIQUITIN--PROTEIN-LIGASE-RXN|NUCLEOTIDE-PYROPHOSPHATASE-RXN|RXN-12611|PANTEPADENYLYLTRAN-RXN|RXN-14139|RXN-9386|RXN-9623|2.5.1.39-RXN|4-COUMARATE--COA-LIGASE-RXN|RXN-8654|ASPARAGINE--TRNA-LIGASE-RXN|GLUTAMINE--TRNA-LIGASE-RXN|GPPS|GLCUR1PUT|6.3.4.10-RXN|ARGSUCCINSYN-RXN|RXN-2001|2.7.7.13-RXN|DGTD|THREONINE--TRNA-LIGASE-RXN|RXN-17917|GGPS|METHIONINE--TRNA-LIGASE-RXN|6.2.1.34-RXN|XANPRIBOSYLTRAN-RXN|RXN-12978|NICONUCADENYLYLTRAN-RXN|RXN-10919|RXN-4305|FADSYN-RXN|ALANINE--TRNA-LIGASE-RXN|RXN-14140|RME256|RME255|RXN0-5107|DNA-DIRECTED-DNA-POLYMERASE-RXN|RXN0-7239|UTPPH|RXN0-2161|4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|RXN-9644|GSADENYLATION-RXN|RXN0-7238|RXN-12720|ADENYLATECYC-RXN|PROLINE--TRNA-LIGASE-RXN|NTPD|2.7.7.14-RXN|QUINOPRIBOTRANS-RXN|VALINE--TRNA-LIGASE-RXN|RXN-1126|S-ADENMETSYN-RXN|RXN-16165|UG1PUT|H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN|FPPSYN-RXN|DUTNH|FARNESYLTRANSTRANSFERASE-RXN|P-PANTOCYSLIG-RXN|RXN66-477|HISTIDINE--TRNA-LIGASE-RXN|RXN66-474|RXN-12184|RXN-13290|RNA-LIGASE-ATP-RXN|TYROSINE--TRNA-LIGASE-RXN|MRNA-GUANYLYLTRANSFERASE-RXN|RXN-16393|RXN-16389|ASNSYNB-RXN|GTP-CYCLOHYDRO-II-RXN|TRANS-RXN0-623|RXN-12610|R06858|2.4.2.12-RXN|H2PTEROATESYNTH-RXN|RXN0-1603|RXN66-474-R-2-HYDROXYSTEARATE/ATP/CO-A//CPD-14717/AMP/PPI.48.|RXN0-5515|RXN-8999|GMP-SYN-NH3-RXN|NAG1P-URIDYLTRANS-RXN|RXNARA-8002|RXN-16401|RXN-16402|RXN66-469|GAMPG|SERINE--TRNA-LIGASE-RXN|LINOLENOYL-RXN|RXN0-6427|PANTOATE-BETA-ALANINE-LIG-RXN|2.7.7.60-RXN|RXN0-7192|RXN-16380|RNA-3-PHOSPHATE-CYCLASE-RXN|RXN-9673|NTDP|CYSTEINE--TRNA-LIGASE-RXN|6.3.4.11-RXN|LEUCINE--TRNA-LIGASE-RXN|RXN-13614|GLYCINE--TRNA-LIGASE-RXN|PHENYLALANINE--TRNA-LIGASE-RXN|ADEC|CDPDIGLYSYN-RXN|LNLNCACOAL|RXN-10|HYPOXANPRIBOSYLTRAN-RXN|RXN-10695|RXN0-5098|PRADP|ISOLEUCINE--TRNA-LIGASE-RXN|RXN-2541|RXN-4303|6.3.4.9-RXN|BIOTINLIG-RXN|PPGPPSYN-RXN|RXN-17127|LNLCCOAL|RXN-12245|RXN-9003|ITPP|RXN-17925|GLURS-RXN|RXN0-6382|FACOAL18111Z|DUTP-PYROP-RXN|RXN0-385}} | + | |
− | {{#set: reversible reaction associated=RXN1F-144|GUANYLCYC-RXN|RNA-DIRECTED-DNA-POLYMERASE-RXN|ATPPHOSPHORIBOSYLTRANS-RXN|RXN-3701|GBDP|RXN1F-66|2.7.7.11-RXN|2.5.1.58-RXN|TCM3|RXN-13323|OROPRIBTRANS-RXN|TCP26|SULFATE-ADENYLYLTRANS-RXN|RXN0-5180|RXN-16415|RXN-7673|PRTRANS-RXN|PRPPAMIDOTRANS-RXN|UTPHEXPURIDYLYLTRANS-RXN|DNA-DIRECTED-RNA-POLYMERASE-RXN|DTDPGLUCOSEPP-RXN|GUANPRIBOSYLTRAN-RXN|GLUC1PURIDYLTRANS-RXN|orPRT|TCX10|2.7.1.90-RXN|GPPSYN-RXN|POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN|2.7.7.44-RXN}} | + | |
Genes have been associated with this reaction based on different elements listed below.